Search Results - "Duan, ZhiJun"

A three-dimensional model of the yeast genome by Schutz, Kevin, McIlwain, Sean, Shendure, Jay, Kim, Yoo Jung, Andronescu, Mirela, Fields, Stanley, Blau, C. Anthony, Lee, Choli, Duan, Zhijun, Noble, William S

“…Layered on top of information conveyed by DNA sequence and chromatin are higher order structures that encompass portions of chromosomes, entire chromosomes,…”
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The Local Defender and Functional Mediator: Gut Microbiome by Yang, Hang, Duan, Zhijun

“…The gut microbiome has been developing and making adaption all the time, which is consistent with their host from the initial colonization at birth or earlier…”
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Trans- and cis-acting effects of Firre on epigenetic features of the inactive X chromosome by Fang, He, Bonora, Giancarlo, Lewandowski, Jordan P., Thakur, Jitendra, Filippova, Galina N., Henikoff, Steven, Shendure, Jay, Duan, Zhijun, Rinn, John L., Deng, Xinxian, Noble, William S., Disteche, Christine M.

“…Firre encodes a lncRNA involved in nuclear organization. Here, we show that Firre RNA expressed from the active X chromosome maintains histone H3K27me3…”
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Bipartite structure of the inactive mouse X chromosome by Deng, Xinxian, Ma, Wenxiu, Ramani, Vijay, Hill, Andrew, Yang, Fan, Ay, Ferhat, Berletch, Joel B, Blau, Carl Anthony, Shendure, Jay, Duan, Zhijun, Noble, William S, Disteche, Christine M

“…In mammals, one of the female X chromosomes and all imprinted genes are expressed exclusively from a single allele in somatic cells. To evaluate structural…”
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Comparison of Esophageal Dysmotility and Reflux Burden in Patients with Different Metabolic Obesity Phenotypes Based on High-Resolution Impedance Manometry and 24-h Impedance-pH by He, Tao, Zhang, Mingjie, Tong, Menghan, Duan, Zhijun

“…The relationship between the metabolically healthy obesity (MHO) phenotype and the occurrence of gastroesophageal reflux disease (GERD) and inefficient…”
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Understanding Spatial Genome Organization： Methods and Insights by Ramani, Vijay, Shendure, Jay, Duan, Zhijun

“…The manner by which eukaryotic genomes are packaged into nuclei while maintaining crucial nuclear functions remains one of the fundamental mysteries in…”
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Activation of α7nAChR preserves intestinal barrier integrity by enhancing the HO-1 / STAT3 signaling to inhibit NF-κB activation in mice by Lei, Wei, Zhao, Changcheng, Sun, Jiasen, Jin, Yanling, Duan, Zhijun

“…Activation of alpha-7 nicotinic acetylcholine receptor (α7nAChR) can inhibit a systemic inflammatory response and preserve intestinal barrier integrity. This…”
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Capturing cell type-specific chromatin compartment patterns by applying topic modeling to single-cell Hi-C data by Kim, Hyeon-Jin, Yardimci, Galip Gürkan, Bonora, Giancarlo, Ramani, Vijay, Liu, Jie, Qiu, Ruolan, Lee, Choli, Hesson, Jennifer, Ware, Carol B, Shendure, Jay, Duan, Zhijun, Noble, William Stafford

“…Single-cell Hi-C (scHi-C) interrogates genome-wide chromatin interaction in individual cells, allowing us to gain insights into 3D genome organization…”
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Fine-scale chromatin interaction maps reveal the cis-regulatory landscape of human lincRNA genes by Ma, Wenxiu, Ay, Ferhat, Lee, Choli, Gulsoy, Gunhan, Deng, Xinxian, Cook, Savannah, Hesson, Jennifer, Cavanaugh, Christopher, Ware, Carol B, Krumm, Anton, Shendure, Jay, Blau, Carl Anthony, Disteche, Christine M, Noble, William S, Duan, Zhijun

“…Targeted DNase Hi-C uses DNase I instead of restriction enzymes for chromatin fragmentation and improves the resolution of chromatin interaction maps…”
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Nomogram for predicting reflux esophagitis with routine metabolic parameters: a retrospective study by He, Tao, Sun, Xiaoyu, Duan, Zhijun

“…The prevalence of reflux esophagitis (RE) is relatively high around the world. We investigated routine metabolic parameters for associations with RE prevalence…”
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Taurocholic acid is an active promoting factor, not just a biomarker of progression of liver cirrhosis: evidence from a human metabolomic study and in vitro experiments by Liu, Zhimin, Zhang, Zhifeng, Huang, Mei, Sun, Xiaoping, Liu, Bojia, Guo, Qiyang, Chang, Qingshan, Duan, Zhijun

“…Previous studies have indicated that bile acid is associated with progression of liver cirrhosis. However, the particular role of specific bile acid in the…”
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Using deep learning to assess the function of gastroesophageal flap valve according to the Hill classification system by Ge, Zhenyang, Fang, Youjiang, Chang, Jiuyang, Yu, Zequn, Qiao, Yu, Zhang, Jing, Yang, Xin, Duan, Zhijun

“…BACKGROUNDThe endoscopic Hill classification of the gastroesophageal flap valve (GEFV) is of great importance for understanding the functional status of the…”
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Form and function of topologically associating genomic domains in budding yeast by Eser, Umut, Chandler-Brown, Devon, Ay, Ferhat, Straight, Aaron F., Duan, Zhijun, Noble, William Stafford, Skotheim, Jan M.

“…The genome of metazoan cells is organized into topologically associating domains (TADs) that have similar histone modifications, transcription level, and DNA…”
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Contributions of HO-1-Dependent MAPK to Regulating Intestinal Barrier Disruption by Zhang, Zhenling, Zhang, Qiuping, Li, Fang, Xin, Yi, Duan, Zhijun

“…The mitogen-activated protein kinase (MAPK) pathway controls intestinal epithelial barrier permeability by regulating tight junctions (TJs) and epithelial…”
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The genome in space and time: Does form always follow function? by Duan, Zhijun, Blau, Carl Anthony

“…Recent systematic studies using newly developed genomic approaches have revealed common mechanisms and principles that underpin the spatial organization of…”
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Single-cell landscape of nuclear configuration and gene expression during stem cell differentiation and X inactivation by Bonora, Giancarlo, Ramani, Vijay, Singh, Ritambhara, Fang, He, Jackson, Dana L, Srivatsan, Sanjay, Qiu, Ruolan, Lee, Choli, Trapnell, Cole, Shendure, Jay, Duan, Zhijun, Deng, Xinxian, Noble, William S, Disteche, Christine M

“…Mammalian development is associated with extensive changes in gene expression, chromatin accessibility, and nuclear structure. Here, we follow such changes…”
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XRCC5 cooperates with p300 to promote cyclooxygenase-2 expression and tumor growth in colon cancers by Zhang, Zhifeng, Zheng, Fufu, Yu, Zhenlong, Hao, Jiajiao, Chen, Miao, Yu, Wendan, Guo, Wei, Chen, Yiming, Huang, Wenlin, Duan, Zhijun, Deng, Wuguo

“…Cyclooxygenase (COX) is the rate-limiting enzyme in prostaglandins (PGs) biosynthesis. Previous studies indicate that COX-2, one of the isoforms of COX, is…”
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Overexpression of P-glycoprotein, MRP2, and CYP3A4 impairs intestinal absorption of octreotide in rats with portal hypertension by Sun, Xiaoyu, Tang, Shunxiong, Hou, Binbin, Duan, Zhijun, Liu, Zhen, Li, Yang, He, Shoucheng, Wang, Qiuming, Chang, Qingyong

“…Portal hypertension (PH) is the main cause of complications and death in liver cirrhosis. The effect of oral administration of octreotide (OCT), a drug that…”
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Denoising Method for Seismic Co-Band Noise Based on a U-Net Network Combined with a Residual Dense Block by Cai, Jianxian, Wang, Li, Zheng, Jiangshan, Duan, Zhijun, Li, Ling, Chen, Ning

“…To address the problem of waveform distortion in the existing seismic signal denoising method when removing co-band noise, further improving the…”
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The Protective Effect of Heme Oxygenase-1 against Intestinal Barrier Dysfunction in Cholestatic Liver Injury Is Associated with NF-κB Inhibition by Zhang, Lijing, Zhang, Zhenling, Liu, Bojia, Jin, Yanling, Tian, Yan, Xin, Yi, Duan, Zhijun

“…Heme oxygenase-1 (HO-1) is reported to protect against liver injury, but little is known about its effect on the intestinal barrier in cholestatic liver…”
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