Search Results - "Duan, Yongjia"
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PARylation regulates stress granule dynamics, phase separation, and neurotoxicity of disease-related RNA-binding proteins
Published in Cell research (01-03-2019)“…Mutations in RNA-binding proteins (RBPs) localized in ribonucleoprotein (RNP) granules, such as hnRNP A1 and TDP-43, promote aberrant protein aggregation,…”
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Stress Induces Dynamic, Cytotoxicity-Antagonizing TDP-43 Nuclear Bodies via Paraspeckle LncRNA NEAT1-Mediated Liquid-Liquid Phase Separation
Published in Molecular cell (06-08-2020)“…Despite the prominent role of TDP-43 in neurodegeneration, its physiological and pathological functions are not fully understood. Here, we report an unexpected…”
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Mycobacterium tuberculosis suppresses host antimicrobial peptides by dehydrogenating L-alanine
Published in Nature communications (17-05-2024)“…Antimicrobial peptides (AMPs), ancient scavengers of bacteria, are very poorly induced in macrophages infected by Mycobacterium tuberculosis ( M. tuberculosis…”
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Inhibition of the MEK/ERK pathway suppresses immune overactivation and mitigates TDP-43 toxicity in a Drosophila model of ALS
Published in Immunity & ageing (20-06-2023)“…TDP-43 is an important DNA/RNA-binding protein that is associated with age-related neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS) and…”
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Distinct multilevel misregulations of Parkin and PINK1 revealed in cell and animal models of TDP-43 proteinopathy
Published in Cell death & disease (20-09-2018)“…Parkin and PINK1 play an important role in mitochondrial quality control, whose malfunction may also be involved in the pathogenesis of amyotrophic lateral…”
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Mycobacterium tuberculosis inhibits METTL14-mediated m6A methylation of Nox2 mRNA and suppresses anti-TB immunity
Published in Cell discovery (29-03-2024)“…Internal N 6 -methyladenosine (m 6 A) modifications are among the most abundant modifications of messenger RNA, playing a critical role in diverse biological…”
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For the sake of my job security: examining the effect of age-based stereotype threat on older workers’ knowledge hiding
Published in Journal of knowledge management (09-10-2024)“…Purpose Organizations can greatly benefit from the transfer of knowledge from older employees to younger generations. However, older workers often hesitate to…”
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CHMP2B regulates TDP-43 phosphorylation and cytotoxicity independent of autophagy via CK1
Published in The Journal of cell biology (03-01-2022)“…The ESCRT protein CHMP2B and the RNA-binding protein TDP-43 are both associated with ALS and FTD. The pathogenicity of CHMP2B has mainly been considered a…”
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Liquid-liquid phase separation of TRAF6 promotes anti-TB immunity
Published in Science bulletin (Beijing) (27-08-2024)“…[Display omitted]…”
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Communication Technology Use for Work at Home during Off-job Time and Work–Family Conflict: The Roles of Family Support and Psychological Detachment
Published in Anales de psicología (Murcia, Spain) (01-01-2017)“…This article studies the influence of communication technology use for work at home during off-job time on work-family conflict based on work-family border…”
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Supervisory Mentoring and Newcomers' Work Engagement: The Mediating Role of Basic Psychological Need Satisfaction
Published in Social behavior and personality (01-10-2018)“…We aimed to determine the extent to which the 3 dimensions of basic psychological need satisfaction (i.e., autonomy, competence, and relatedness) explain the…”
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Impression management tactics of protégés and mentors' knowledge-sharing behavior
Published in Social behavior and personality (01-12-2016)“…Given its contribution to organizational knowledge management, a mentoring program is considered to be beneficial for knowledge sharing within organizations…”
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Image Perception and Promotion of Chuancais Museum Based on Online Big Data
Published in 2024 4th International Conference on Big Data Engineering and Education (BDEE) (09-08-2024)“…Chuancais Museum plays an important role in the dissemination of Sichuan cuisine culture. Building a good tourism image is crucial for the long-term…”
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Conference Proceeding -
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Mycobacterium tuberculosis inhibits METTL14-mediated m 6 A methylation of Nox2 mRNA and suppresses anti-TB immunity
Published in Cell discovery (29-03-2024)“…Internal N -methyladenosine (m A) modifications are among the most abundant modifications of messenger RNA, playing a critical role in diverse biological and…”
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Poly(ADP-ribosylation) regulates stress granule dynamics, phase separation, and neurotoxicity of disease-related RNA-binding proteins
Published in IBRO reports (01-09-2019)Get full text
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