Search Results - "Duan, ShuMin"

mTOR‐mediated metabolic reprogramming shapes distinct microglia functions in response to lipopolysaccharide and ATP by Hu, Yaling, Mai, Weihao, Chen, Lunhao, Cao, Kelei, Zhang, Bin, Zhang, Zhenjie, Liu, Yijun, Lou, Huifang, Duan, Shumin, Gao, Zhihua

“…Microglia constantly survey the brain microenvironment and rapidly adopt different phenotypes in response to environmental stimuli. Such dynamic functions…”
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Cannabinoid CB1 receptors in the amygdalar cholecystokinin glutamatergic afferents to nucleus accumbens modulate depressive-like behavior by Shen, Chen-Jie, Zheng, Di, Li, Ke-Xin, Yang, Jian-Ming, Pan, Hao-Qi, Yu, Xiao-Dan, Fu, Jia-Yu, Zhu, Yi, Sun, Qi-Xin, Tang, Meng-Yu, Zhang, Ying, Sun, Peng, Xie, Yi, Duan, Shumin, Hu, Hailan, Li, Xiao-Ming

“…Major depressive disorder is a devastating psychiatric disease that afflicts up to 17% of the world’s population. Postmortem brain analyses and imaging studies…”
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Parabrachial nucleus circuit governs neuropathic pain-like behavior by Sun, Li, Liu, Rui, Guo, Fang, Wen, Man-qing, Ma, Xiao-lin, Li, Kai-yuan, Sun, Hao, Xu, Ceng-lin, Li, Yuan-yuan, Wu, Meng-yin, Zhu, Zheng-gang, Li, Xin-jian, Yu, Yan-qin, Chen, Zhong, Li, Xiang-yao, Duan, Shumin

“…The lateral parabrachial nucleus (LPBN) is known to relay noxious information to the amygdala for processing affective responses. However, it is unclear…”
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NG2 glia-derived GABA release tunes inhibitory synapses and contributes to stress-induced anxiety by Zhang, Xiao, Liu, Yao, Hong, Xiaoqi, Li, Xia, Meshul, Charles K., Moore, Cynthia, Yang, Yabing, Han, Yanfei, Li, Wei-Guang, Qi, Xin, Lou, Huifang, Duan, Shumin, Xu, Tian-Le, Tong, Xiaoping

“…NG2 glia, also known as oligodendrocyte precursor cells (OPCs), play an important role in proliferation and give rise to myelinating oligodendrocytes during…”
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The combined effect of food additive titanium dioxide and lipopolysaccharide on mouse intestinal barrier function after chronic exposure of titanium dioxide-contained feedstuffs by Zhang, Yongliang, Duan, Shumin, Liu, Ying, Wang, Yun

“…Up to 44% of particulates of food-grade titanium dioxide (TiO ) are in nanoscale, while the effect and combined effect of which with other substances on…”
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A Disinhibitory Microcircuit Mediates Conditioned Social Fear in the Prefrontal Cortex by Xu, Haifeng, Liu, Ling, Tian, Yuanyuan, Wang, Jun, Li, Jie, Zheng, Junqiang, Zhao, Hongfei, He, Miao, Xu, Tian-Le, Duan, Shumin, Xu, Han

“…Fear behavior is under tight control of the prefrontal cortex, but the underlying microcircuit mechanism remains elusive. In particular, it is unclear how…”
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Reconstruction of the Hypothalamo-Neurohypophysial System and Functional Dissection of Magnocellular Oxytocin Neurons in the Brain by Zhang, Bin, Qiu, Liyao, Xiao, Wei, Ni, Hong, Chen, Lunhao, Wang, Fan, Mai, Weihao, Wu, Jintao, Bao, Aimin, Hu, Hailan, Gong, Hui, Duan, Shumin, Li, Anan, Gao, Zhihua

“…The hypothalamo-neurohypophysial system (HNS), comprising hypothalamic magnocellular neuroendocrine cells (MNCs) and the neurohypophysis, plays a pivotal role…”
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Organizational principles of amygdalar input-output neuronal circuits by Huang, Limeng, Chen, Yiwen, Jin, Sen, Lin, Li, Duan, Shumin, Si, Ke, Gong, Wei, Julius Zhu, J.

“…The amygdala, one of the most studied brain structures, integrates brain-wide heterogeneous inputs and governs multidimensional outputs to control diverse…”
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Astrocytes contribute to synapse elimination via type 2 inositol 1,4,5-trisphosphate receptor-dependent release of ATP by Yang, Junhua, Yang, Hongbin, Liu, Yali, Li, Xia, Qin, Liming, Lou, Huifang, Duan, Shumin, Wang, Hao

“…Selective elimination of unwanted synapses is vital for the precise formation of neuronal circuits during development, but the underlying mechanisms remain…”
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Glia-derived ATP inversely regulates excitability of pyramidal and CCK-positive neurons by Tan, Zhibing, Liu, Yu, Xi, Wang, Lou, Hui-fang, Zhu, Liya, Guo, Zhifei, Mei, Lin, Duan, Shumin

“…Astrocyte responds to neuronal activity with calcium waves and modulates synaptic transmission through the release of gliotransmitters. However, little is…”
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Depolarized GABAergic Signaling in Subicular Microcircuits Mediates Generalized Seizure in Temporal Lobe Epilepsy by Wang, Yi, Xu, Cenglin, Xu, Zhenghao, Ji, Caihong, Liang, Jiao, Wang, Ying, Chen, Bin, Wu, Xiaohua, Gao, Feng, Wang, Shuang, Guo, Yi, Li, Xiaoming, Luo, Jianhong, Duan, Shumin, Chen, Zhong

“…Secondary generalized seizure (sGS) is a major source of disability in temporal lobe epilepsy (TLE) with unclear cellular/circuit mechanisms. Here we found…”
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Microglial migration mediated by ATP-induced ATP release from lysosomes by Dou, Ying, Wu, Hang-jun, Li, Hui-quan, Qin, Song, Wang, Yin-er, Li, Jing, Lou, Hui-fang, Chen, Zhong, Li, Xiao-ming, Luo, Qing-ming, Duan, Shumin

“…Microglia are highly motile cells that act as the main form of active immune defense in the central nervous system. Attracted by factors released from damaged…”
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Activated astrocytes attenuate neocortical seizures in rodent models through driving Na+-K+-ATPase by Zhao, Junli, Sun, Jinyi, Zheng, Yang, Zheng, Yanrong, Shao, Yuying, Li, Yulan, Fei, Fan, Xu, Cenglin, Liu, Xiuxiu, Wang, Shuang, Ruan, Yeping, Liu, Jinggen, Duan, Shumin, Chen, Zhong, Wang, Yi

“…Epileptic seizures are widely regarded to occur as a result of the excitation-inhibition imbalance from a neuro-centric view. Although astrocyte-neuron…”
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Histamine H1 receptor deletion in cholinergic neurons induces sensorimotor gating ability deficit and social impairments in mice by Cheng, Li, Xu, Cenglin, Wang, Lu, An, Dadao, Jiang, Lei, Zheng, Yanrong, Xu, Yixin, Wang, Yi, Wang, Yujing, Zhang, Kuo, Wang, Xiaodong, Zhang, Xiangnan, Bao, Aimin, Zhou, Yudong, Yang, Jingyu, Duan, Shumin, Swaab, Dick F., Hu, Weiwei, Chen, Zhong

“…Negative symptoms in schizophrenia strongly contribute to poor functional outcomes, however its pathogenesis is still unclear. Here, we found that histamine H…”
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Activation of astrocytes in hippocampus decreases fear memory through adenosine A1 receptors by Li, Yulan, Li, Lixuan, Wu, Jintao, Zhu, Zhenggang, Feng, Xiang, Qin, Liming, Zhu, Yuwei, Sun, Li, Liu, Yijun, Qiu, Zilong, Duan, Shumin, Yu, Yan-Qin

“…Astrocytes respond to and regulate neuronal activity, yet their role in mammalian behavior remains incompletely understood. Especially unclear is whether, and…”
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Direct Septum-Hippocampus Cholinergic Circuit Attenuates Seizure Through Driving Somatostatin Inhibition by Wang, Ying, Wang, Yi, Xu, Cenglin, Wang, Shuang, Tan, Na, Chen, Cong, Chen, Liying, Wu, Xiaohua, Fei, Fan, Cheng, Heming, Lin, Wenkai, Qi, Yingbei, Chen, Bin, Liang, Jiao, Zhao, Junli, Xu, Zhenghao, Guo, Yi, Zhang, Shihong, Li, Xiaoming, Zhou, Yudong, Duan, Shumin, Chen, Zhong

“…Previous studies indicated the involvement of cholinergic neurons in seizure; however, the specific role of the medial septum (MS)-hippocampus cholinergic…”
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Oral intake of titanium dioxide nanoparticles affect the course and prognosis of ulcerative colitis in mice: involvement of the ROS-TXNIP-NLRP3 inflammasome pathway by Duan, Shumin, Wang, Hongbo, Gao, Yanjun, Wang, Xiang, Lyu, Lizhi, Wang, Yun

“…Titanium dioxide (TiO ), no matter in nanoscale or micron sizes, has been widely used in food industry as additives for decades. Given the potential impact of…”
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P2X7 receptors: Properties and relevance to CNS function by Duan, Shumin, Neary, Joseph T.

“…Among seven members of P2X ionotropic receptors activated by extracellular ATP, the P2X7 subtype is unique in that it can function as a cation channel, a…”
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Regulated ATP release from astrocytes through lysosome exocytosis by Xu, Tao, Zhang, Zhijun, Duan, Shumin, Song, Aihong, Zhou, Wei, Gu, Xiao-song, Chen, Gang, Wang, Wei, Luo, Qingming

“…Release of ATP from astrocytes is required for Ca2+ wave propagation among astrocytes and for feedback modulation of synaptic functions. However, the mechanism…”
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A novel cortico-intrathalamic circuit for flight behavior by Dong, Ping, Wang, Hao, Shen, Xiao-Fan, Jiang, Ping, Zhu, Xu-Tao, Li, Yue, Gao, Jia-Hao, Lin, Shan, Huang, Yue, He, Xiao-Bin, Xu, Fu-Qiang, Duan, Shumin, Lian, Hong, Wang, Hao, Chen, Jiadong, Li, Xiao-Ming

“…Flight, an active fear response to imminent threat, is dependent on the rapid risk assessment of sensory information processed by the cortex. The thalamic…”
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