Search Results - "Duan, Shiteng"

Siglecs as Immune Cell Checkpoints in Disease by Duan, Shiteng, Paulson, James C

“…Sialic acid-binding immunoglobulin-type lectins (Siglecs) are expressed on the majority of white blood cells of the immune system and play critical roles in…”
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Human CD22 Inhibits Murine B Cell Receptor Activation in a Human CD22 Transgenic Mouse Model by Bednar, Kyle J, Shanina, Elena, Ballet, Romain, Connors, Edward P, Duan, Shiteng, Juan, Joana, Arlian, Britni M, Kulis, Michael D, Butcher, Eugene C, Fung-Leung, Wai-Ping, Rao, Tadimeti S, Paulson, James C, Macauley, Matthew S

“…CD22, a sialic acid-binding Ig-type lectin (Siglec) family member, is an inhibitory coreceptor of the BCR with established roles in health and disease. The…”
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Exploiting CD22 on antigen-specific B cells to prevent allergy to the major peanut allergen Ara h 2 by Orgel, Kelly A., BS, Duan, Shiteng, BS, Wright, Benjamin L., MD, Maleki, Soheila J., PhD, Wolf, John C., PhD, Vickery, Brian P., MD, Burks, A. Wesley, MD, Paulson, James C., PhD, Kulis, Mike D., PhD, Macauley, Matthew S., PhD

“…Taken together, these results suggest that Ah2 STALs induce antigen-specific tolerance toward the major peanut allergen, severely blunting Ah2 sIgE and sIgG1…”
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Repression of phagocytosis by human CD33 is not conserved with mouse CD33 by Bhattacherjee, Abhishek, Rodrigues, Emily, Jung, Jaesoo, Luzentales-Simpson, Matthew, Enterina, Jhon R., Galleguillos, Danny, St. Laurent, Chris D., Nakhaei-Nejad, Maryam, Fuchsberger, Felix F., Streith, Laura, Wang, Qian, Kawasaki, Norihito, Duan, Shiteng, Bains, Arjun, Paulson, James C., Rademacher, Christoph, Giuliani, Fabrizio, Sipione, Simonetta, Macauley, Matthew S.

“…CD33 is an immunomodulatory receptor linked to Alzheimer’s disease (AD) susceptibility via regulation of phagocytosis in microglia. Divergent features between…”
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Siglec-Engaging Tolerance-Inducing Antigenic Liposomes (STALs) in the Prevention of Peanut Allergy by Orgel, Kelly, BS, Duan, Shiteng, BS, Paulson, James C., PhD, Burks, A. Wesley, MD, FAAAAI, Vickery, Brian P., MD, FAAAAI, Kulis, Michael D., PhD, Macauley, Matthew S., PhD

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Author Correction: Repression of phagocytosis by human CD33 is not conserved with mouse CD33 by Bhattacherjee, Abhishek, Rodrigues, Emily, Jung, Jaesoo, Luzentales-Simpson, Matthew, Enterina, Jhon R., Galleguillos, Danny, St. Laurent, Chris D., Nakhaei-Nejad, Maryam, Fuchsberger, Felix F., Streith, Laura, Wang, Qian, Kawasaki, Norihito, Duan, Shiteng, Bains, Arjun, Paulson, James C., Rademacher, Christoph, Giuliani, Fabrizio, Sipione, Simonetta, Macauley, Matthew S.

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Suppressing Immune Responses Using Siglec Ligand-Decorated Anti-receptor Antibodies by Islam, Maidul, Arlian, Britni M., Pfrengle, Fabian, Duan, Shiteng, Smith, Scott A., Paulson, James C.

“…The sialic acid-binding immunoglobulin-type lectins (Siglecs) are expressed predominantly on white blood cells and participate in immune cell recognition of…”
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CD33 recruitment inhibits IgE-mediated anaphylaxis and desensitizes mast cells to allergen by Duan, Shiteng, Koziol-White, Cynthia J, Jester, Jr, William F, Smith, Scott A, Nycholat, Corwin M, Macauley, Matthew S, Panettieri, Jr, Reynold A, Paulson, James C

“…Allergen immunotherapy for patients with allergies begins with weekly escalating doses of allergen under medical supervision to monitor and treat IgE mast…”
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Nanoparticles Displaying Allergen and Siglec-8 Ligands Suppress IgE-FcεRI-Mediated Anaphylaxis and Desensitize Mast Cells to Subsequent Antigen Challenge by Duan, Shiteng, Arlian, Britni M, Nycholat, Corwin M, Wei, Yadong, Tateno, Hiroaki, Smith, Scott A, Macauley, Matthew S, Zhu, Zhou, Bochner, Bruce S, Paulson, James C

“…Siglec-8 is an inhibitory receptor expressed on eosinophils and mast cells. In this study, we took advantage of a novel Siglec-8 transgenic mouse model to…”
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A Sulfonamide Sialoside Analogue for Targeting Siglec‑8 and -F on Immune Cells by Nycholat, Corwin M, Duan, Shiteng, Knuplez, Eva, Worth, Charli, Elich, Mila, Yao, Anzhi, O’Sullivan, Jeremy, McBride, Ryan, Wei, Yadong, Fernandes, Steve M, Zhu, Zhou, Schnaar, Ronald L, Bochner, Bruce S, Paulson, James C

“…The Siglec family of cell surface receptors have emerged as attractive targets for cell-directed therapies due to their restricted expression on immune cells,…”
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SIGLEC-3 (CD33) serves as an immune checkpoint receptor for HBV infection by Tsai, Tsung-Yu, Huang, Ming-Ting, Sung, Pei-Shan, Peng, Cheng-Yuan, Tao, Mi-Hua, Yang, Hwai-I, Chang, Wei-Chiao, Yang, An-Suei, Yu, Chung-Ming, Lin, Ya-Ping, Bau, Ching-Yu, Huang, Chih-Jen, Pan, Mei-Hung, Wu, Chung-Yi, Hsiao, Chwan-Deng, Yeh, Yi-Hung, Duan, Shiteng, Paulson, James C, Hsieh, Shie-Liang

“…Chronic hepatitis B (CHB) infection is rarely eradicated by current antiviral nucleos(t)ide analogues. We found that [alpha]2,6-biantennary sialoglycans of HBV…”
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Exploiting Siglecs to Treat Allergic Diseases by Duan, Shiteng

“…Allergy, or Type I hypersensitivity, is a major public health concern worldwide. The mast cell-FcεRI-IgE axis is central in the manifestation of immediate…”
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Harnessing Siglecs to Induce Immune Tolerance by Paulson, James C., Arlian, Britni, Duan, Shiteng, Macauley, Matthew, Nycholat, Corwin M., Pang, Lijuan, Srivastava, Amrita

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SIGLEC-3 (CD33) serves as an immune checkpoint receptor for HBV infection by Tsai, Tsung-Yu, Huang, Ming-Ting, Sung, Pei-Shan, Peng, Cheng-Yuan, Tao, Mi-Hua, Yang, Hwai-I, Chang, Wei-Chiao, Yang, An-Suei, Yu, Chung-Ming, Lin, Ya-Ping, Bau, Ching-Yu, Huang, Chih-Jen, Pan, Mei-Hung, Wu, Chung-Yi, Hsiao, Chwan-Deng, Yeh, Yi-Hung, Duan, Shiteng, Paulson, James C, Hsieh, Shie-Liang

“…Chronic hepatitis B (CHB) infection is rarely eradicated by current antiviral nucleos(t)ide analogues. We found that α2,6-biantennary sialoglycans of HBV…”
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SIGLEC-3 by Tsai, Tsung-Yu, Huang, Ming-Ting, Sung, Pei-Shan, Peng, Cheng-Yuan, Tao, Mi-Hua, Yang, Hwai-I, Chang, Wei-Chiao, Yang, An-Suei, Yu, Chung-Ming, Lin, Ya-Ping, Bau, Ching-Yu, Huang, Chih-Jen, Pan, Mei-Hung, Wu, Chung-Yi, Hsiao, Chwan-Deng, Yeh, Yi-Hung, Duan, Shiteng, Paulson, James C, Hsieh, Shie-Liang

“…Chronic hepatitis B (CHB) infection is rarely eradicated by current antiviral nucleos(t)ide analogues. We found that [alpha]2,6-biantennary sialoglycans of HBV…”
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Antigenic Liposomes for Generation of Disease-specific Antibodies by Bednar, Kyle J, Hardy, Lakeya, Smeekens, Johanna, Raghuwanshi, Dharmendra, Duan, Shiteng, Kulis, Mike D, Macauley, Matthew S

“…Antibody responses provide critical protective immunity to a wide array of pathogens. There remains a high interest in generating robust antibodies for…”
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Abstract 2359: New insights into targeting the CD200R1 pathway in T and NK cells using 23ME-00610 as a single agent or in combination by Kumar, Mithra R., Duan, Shiteng, Yadav, Shruti, Jarret, Abigail, Yan, Zhonghao, Fenaux, Jill, Kinisu, Martin, Yi, Zuoan, Poggio, Mauro, Collins, Patrick, Symons, Antony, Blanco, Lorena Riol, Schmidt, Maike, Majeed, Sophia, Diep, Anh, Lee, Clarissa

“…23ME-00610 is a monoclonal antibody that is being evaluated as a single agent in a Phase 1/2a clinical trial for advanced solid malignancies (NCT05199272). It…”
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Using Siglec-engaging Tolerance-inducing Antigenic Liposomes (STALs) to reduce memory B cell responses to the major peanut allergen Ara h 2 by Hardy, LaKeya C., Orgel, Kelly, Duan, Shiteng, Maleki, Soheila J., Burks, A. Wesley, Paulson, James C., Macauley, Matthew, Kulis, Michael D.

“…[...]mice were challenged with a high dose of Ah2. Conclusions A single dose of Ah2 STALs suppressed the memory B-cell response to Ah2, demonstrating viability…”
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Human CD22 Inhibits Murine B-cell Receptor Activation in a Human CD22 Transgenic Mouse Model1 by Bednar, Kyle J, Shanina, Elena, Ballet, Romain, Connors, Edward P, Duan, Shiteng, Juan, Joana, Arlian, Britni M., Kulis, Michael D, Butcher, Eugene C, Fung-Leung, Wai-Ping, Rao, Tadimeti S, Paulson, James C, Macauley, Matthew S

“…CD22, a sialic-acid binding immunoglobulin type-lectin (Siglec) family member, is an inhibitory co-receptor of the B-cell receptor (BCR) with established roles…”
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Antigenic Liposomes for Generation of Disease-specific Antibodies by Bednar, Kyle J., Hardy, Lakeya, Smeekens, Johanna, Raghuwanshi, Dharmendra, Duan, Shiteng, Kulis, Mike D., Macauley, Matthew S.

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