Search Results - "Duan, Qiuhong"

The role of branched chain amino acids metabolic disorders in tumorigenesis and progression by Wang, Jingtong, Wang, Wei, Zhu, Feng, Duan, Qiuhong

“…Branched-chain amino acids (BCAAs) are essential amino acids in human bodies. They have complex metabolic pathways and various metabolites. Both BCAAs and its…”
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Phosphorylation of BCKDK of BCAA catabolism at Y246 by Src promotes metastasis of colorectal cancer by Tian, Qin, Yuan, Ping, Quan, Chuntao, Li, Mingyang, Xiao, Juanjuan, Zhang, Lu, Lu, Hui, Ma, Tengfei, Zou, Ling, Wang, Fei, Xue, Peipei, Ni, Xiaofang, Wang, Wei, Liu, Lin, Wang, Zhe, Zhu, Feng, Duan, Qiuhong

“…Branched-chain α-keto acid dehydrogenase kinase (BCKDK), the key enzyme of branched-chain amino acids (BCAAs) metabolism, has been reported to promote…”
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YANK2 activated by Fyn promotes glioma tumorigenesis via the mTOR-independent p70S6K activation pathway by Shi, Yue, Cheng, Yue, Wang, Wei, Tang, Liu, Li, Wensheng, Zhang, Liyuan, Yuan, Zheng, Zhu, Feng, Duan, Qiuhong

“…Glioma, particularly glioblastomas (GBM), is incurable brain tumor. The most targeted receptor tyrosine kinase (RTKs) drugs did not bring benefit to GBM…”
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Research Advances in the Molecular Functions and Relevant Diseases of TAOKs, Novel STE20 Kinase Family Members by Ye, Junjie, Shi, Mingjun, Chen, Wei, Zhu, Feng, Duan, Qiuhong

“…As serine/threonine-protein kinases, Thousand and One Kinases(TAOKs) are members of the GCKlike superfamily, one of two well-known branches of the Ste20 kinase…”
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Glioma-derived LRIG3 interacts with NETO2 in tumor-associated macrophages to modulate microenvironment and suppress tumor growth by Li, Youwei, Wang, Wei, Hou, Xiaoshuang, Huang, Wenda, Zhang, Po, He, Yue, Wang, Baofeng, Duan, Qiuhong, Mao, Feng, Guo, Dongsheng

“…Tumor-associated macrophages (TAMs) account for 30–50% of glioma microenvironment. The interaction between glioma tumor cells and TAMs can promote tumor…”
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The role of T-LAK cell-originated protein kinase in targeted cancer therapy by Zhang, Lu, Wang, Fei, Yi, Huijun, Ermakova, Svetlana P., Malyarenko, Olesya S., Mo, Jianmei, Huang, Yingze, Duan, Qiuhong, Xiao, Juanjuan, Zhu, Feng

“…Targeted therapy has gradually become the first-line clinical tumor therapy due to its high specificity and low rate of side effects. TOPK (T-LAK…”
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Protein Kinases as Tumor Biomarkers and Therapeutic Targets by Quan, Chuntao, Xiao, Juanjuan, Liu, Lin, Duan, Qiuhong, Yuan, Ping, Zhu, Feng

“…Over the last three decades, neoplasms have become the largest cause of human mortality due to both high tumor incidence and mortality. Chemotherapy is one of…”
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S645C Point Mutation Suppresses Degradation of EGFR to Promote Progression of Glioblastoma by Huang, Wenda, Zou, Ling, Hao, Zhaonian, Wang, Baofeng, Mao, Feng, Duan, Qiuhong, Guo, Dongsheng

“…Background The tightly controlled activity of EGFR is important for the homeostasis of self-renewal of human tissue. Mutations in the extracellular domain of…”
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LRIG3 Suppresses Angiogenesis by Regulating the PI3K/AKT/VEGFA Signaling Pathway in Glioma by Peng, Chenghao, Chen, Hanmin, Li, Youwei, Yang, Hang, Qin, Peizhong, Ma, Baojun, Duan, Qiuhong, Wang, Baofeng, Mao, Feng, Guo, Dongsheng

“…High levels of microvessel density (MVD) indicate poor prognosis in patients with malignant glioma. Leucine-rich repeats and immunoglobulin-like domains (LRIG)…”
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Inhibiting ALK-TOPK signaling pathway promotes cell apoptosis of ALK-positive NSCLC by Xiao, Juanjuan, Zhang, Lu, Yi, Huijun, Zou, Ling, Mo, Jianmei, Xue, Feng, Zheng, Jinhua, Huang, Yingze, Lu, Hui, Wu, Hansheng, Xue, Peipei, Zhang, Xin, He, Lifei, Li, Zhaoxin, Pang, Shigui, Qiao, Guibin, Duan, Qiuhong, Zhu, Feng

“…T-LAK cell-oriented protein kinase (TOPK) is a potential therapeutic target in tumors. However, its role in anaplastic lymphoma kinase (ALK)-positive non-small…”
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FYN-mediated phosphorylation of BCKDK at Y151 promotes GBM proliferation by increasing the oncogenic metabolite N-acetyl-L-alanine by Zou, Ling, Wang, Wei, Huang, Wenda, Ni, Xiaofang, Li, Wensheng, Cheng, Yue, Tian, Qin, Liu, Lin, Zhu, Feng, Duan, Qiuhong

“…Branched chain α-keto acid dehydrogenase kinase (BCKDK) is a key enzyme involved in the metabolism of branched-chain amino acids (BCAAs). Its potential as a…”
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Meningeal Ewing Sarcoma/Peripheral PNET: Clinicopathological, Immunohistochemical and FISH study of four cases by Ke, Changshu, Duan, Qiuhong, Yang, Hui, Zhu, Feng, Yan, Meng, Xu, San‐peng, Zhou, Sheng, Wan, Feng, Shu, Kai, Lei, Ting, Xia, Li‐ming

“…Meningeal Ewing Sarcoma (ES)/peripheral primitive neuroectodermal tumor (pPNET) is a rare diagnostically challenging small round cell tumor in the CNS. This…”
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Worenine Prevents Solar Ultraviolet–Induced Sunburn by Inhibiting JNK2 by Xiao, Juanjuan, Lu, Hui, Ma, Tengfei, Ni, Xiaofang, Chang, Teding, Liu, Man, Li, Nijie, Lu, Peijiang, Ke, Changshu, Tian, Qin, Zou, Ling, Wang, Fei, Wang, Wei, Zhang, Lu, Yuan, Ping, Liu, Lin, Zhang, Jianmin, Shi, Fei, Duan, Qiuhong, Zhu, Feng

“…Excessive solar ultraviolet (SUV) radiation often causes dermatitis, photoaging, and even skin cancer. In the pathological processes of SUV-induced sunburn,…”
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TOPK is highly expressed in circulating tumor cells, enabling metastasis of prostate cancer by Sun, Huimin, Zhang, Lei, Shi, Changhong, Hu, Peizhen, Yan, Wei, Wang, Zhe, Duan, Qiuhong, Lu, Fan, Qin, Lipeng, Lu, Tao, Xiao, Juanjuan, Wang, Yingmei, Zhu, Feng, Shao, Chen

“…Circulating tumor cells (CTCs) are important for metastasis in prostate cancer. T-LAK cell-originated protein kinase (TOPK) is highly expressed in cancer…”
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The Prognostic and Therapeutic Potential of LRIG3 and Soluble LRIG3 in Glioblastoma by Cheng, Fangling, Zhang, Po, Xiao, Qungen, Li, Youwei, Dong, Minhai, Wang, Heping, Kuang, Dong, He, Yue, Duan, Qiuhong, Mao, Feng, Wang, Baofeng, Guo, Dongsheng

“…Glioblastoma is a highly lethal type of primary brain tumor that exhibits unrestricted growth and aggressive invasion capabilities, leading to a dismal…”
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BCKDK of BCAA Catabolism Cross-talking With the MAPK Pathway Promotes Tumorigenesis of Colorectal Cancer by Xue, Peipei, Zeng, Fanfan, Duan, Qiuhong, Xiao, Juanjuan, Liu, Lin, Yuan, Ping, Fan, Linni, Sun, Huimin, Malyarenko, Olesya S., Lu, Hui, Xiu, Ruijuan, Liu, Shaoqing, Shao, Chen, Zhang, Jianmin, Yan, Wei, Wang, Zhe, Zheng, Jianyong, Zhu, Feng

“…Branched-chain amino acids catabolism plays an important role in human cancers. Colorectal cancer is the third most commonly diagnosed cancer in males and the…”
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Corrigendum: The Prognostic and Therapeutic Potential of LRIG3 and Soluble LRIG3 in Glioblastoma by Cheng, Fangling, Zhang, Po, Xiao, Qungen, Li, Youwei, Dong, Minhai, Wang, Heping, Kuang, Dong, He, Yue, Duan, Qiuhong, Mao, Feng, Wang, Baofeng, Guo, Dongsheng

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Salidroside suppresses solar ultraviolet-induced skin inflammation by targeting cyclooxygenase-2 by Wu, Dan, Yuan, Ping, Ke, Changshu, Xiong, Hua, Chen, Jingwen, Guo, Jinguang, Lu, Mingmin, Ding, Yanyan, Fan, Xiaoming, Duan, Qiuhong, Shi, Fei, Zhu, Feng

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Comparison of 6-hydroxylmelatonin or melatonin in protecting neurons against ischemia/reperfusion-mediated injury by Duan, Qiuhong, Wang, Zhongqiang, Lu, Tao, Chen, Juan, Wang, Ximing

“…:  The protective effect of exogenous melatonin or 6‐hydroxylmelatonin on neurons was examined in N2a cells following exposure to oxygen–glucose–serum…”
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Arachidonic acid can significantly prevent early insulin resistance induced by a high-fat diet by Wu, Mianyun, Wang, Ximing, Duan, Qiuhong, Lu, Tao

“…To investigate whole-body metabolic disorder and hepatic glucose output (HGO) disturbance in rats with insulin resistance induced by a short-term high-fat…”
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