Search Results - "Duan, Lauren"

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  1. 1

    Dynamic Transcriptional Responses to Injury of Regenerative and Non-regenerative Cardiomyocytes Revealed by Single-Nucleus RNA Sequencing by Cui, Miao, Wang, Zhaoning, Chen, Kenian, Shah, Akansha M., Tan, Wei, Duan, Lauren, Sanchez-Ortiz, Efrain, Li, Hui, Xu, Lin, Liu, Ning, Bassel-Duby, Rhonda, Olson, Eric N.

    Published in Developmental cell (06-04-2020)
    “…The adult mammalian heart is incapable of regeneration following injury. In contrast, the neonatal mouse heart can efficiently regenerate during the first week…”
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    Journal Article
  2. 2

    C9orf72 arginine-rich dipeptide repeat proteins disrupt karyopherin-mediated nuclear import by Hayes, Lindsey R, Duan, Lauren, Bowen, Kelly, Kalab, Petr, Rothstein, Jeffrey D

    Published in eLife (02-03-2020)
    “…Disruption of nucleocytoplasmic transport is increasingly implicated in the pathogenesis of neurodegenerative diseases, including ALS caused by a…”
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    Journal Article
  3. 3

    devCellPy is a machine learning-enabled pipeline for automated annotation of complex multilayered single-cell transcriptomic data by Galdos, Francisco X., Xu, Sidra, Goodyer, William R., Duan, Lauren, Huang, Yuhsin V., Lee, Soah, Zhu, Han, Lee, Carissa, Wei, Nicholas, Lee, Daniel, Wu, Sean M.

    Published in Nature communications (07-09-2022)
    “…A major informatic challenge in single cell RNA-sequencing analysis is the precise annotation of datasets where cells exhibit complex multilayered identities…”
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    Abstract Mo062: Cpne5 is Necessary for Normal Sinoatrial Node Function by Dang, Katherine, Ren, Lu, Atzert, Felix, Thai, Phung, Mantri, Sruthi, Duan, Lauren, Beyersdorf, Benjamin, Chiamvimonvat, Nipavan, Wu, Sean, Goodyer, William

    Published in Circulation research (02-08-2024)
    “…Abstract only Background: Cpne5 (Copine 5) is a Ca2+-dependent phospholipid binding protein implicated in membrane trafficking but has no known role within the…”
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    Journal Article
  8. 8

    Abstract P3050: Cpne5 Is Necessary For Normal Murine Sinoatrial Node Function In Vivo by Ren, Lu, Thai, Phung, Mantri, Sruthi, Duan, Lauren, Atzert, Felix, Beyersdorf, Benjamin, Chiamvimonvat, Nipavan, Wu, Sean M, Goodyer, William R

    Published in Circulation research (04-08-2023)
    “…Abstract only Cpne5 ( Copine 5 ) is a Ca 2+ -dependent phospholipid binding protein implicated in membrane trafficking but has no known role within the heart…”
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    Journal Article
  9. 9

    Nuclear RNA binding regulates TDP-43 nuclear localization and passive nuclear export by Duan, Lauren, Zaepfel, Benjamin L., Aksenova, Vasilisa, Dasso, Mary, Rothstein, Jeffrey D., Kalab, Petr, Hayes, Lindsey R.

    Published in Cell reports (Cambridge) (19-07-2022)
    “…Nuclear clearance of the RNA-binding protein TDP-43 is a hallmark of neurodegeneration and an important therapeutic target. Our current understanding of TDP-43…”
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    Journal Article
  10. 10

    Cardiac Development at a Single-Cell Resolution by Wei, Nicholas, Lee, Carissa, Duan, Lauren, Galdos, Francisco X, Samad, Tahmina, Raissadati, Alireza, Goodyer, William R, Wu, Sean M

    “…Mammalian cardiac development is a complex, multistage process. Though traditional lineage tracing studies have characterized the broad trajectories of cardiac…”
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    Journal Article
  11. 11

    Abstract P1001: IGFBP2 Overcomes Cell Contact-mediated Proliferation Inhibition In Human IPSC-derived Cardiomyocytes by Lee, Soah, Heinrich, Paul, Lee, Daniel, Goodyer, William R, Galdos, Francisco X, Zhu, Han, Samad, Tahmina, Xu, Sidra, Lee, Carissa, Duan, Lauren, Wu, Sean M

    Published in Circulation research (05-08-2022)
    “…Introduction and HypothesisHuman induced pluripotent stem cells (hiPSCs) and their derivatives provide a promising cellular source for regenerative cardiac…”
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    Journal Article
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