Search Results - "Duan, Chuanzhi"

Identification of immune-infiltrated hub genes as potential biomarkers of Moyamoya disease by bioinformatics analysis by Jin, Fa, Duan, Chuanzhi

“…Moyamoya disease (MMD) is a rare chronic progressive cerebrovascular disease. Recent studies have shown that autoimmune inflammation may also be an important…”
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Heat shock protein 22 modulates NRF1/TFAM-dependent mitochondrial biogenesis and DRP1-sparked mitochondrial apoptosis through AMPK-PGC1α signaling pathway to alleviate the early brain injury of subarachnoid hemorrhage in rats by Fan, Haiyan, Ding, Rui, Liu, Wenchao, zhang, Xin, Li, Ran, Wei, Boyang, Su, Shixing, Jin, Fa, Wei, Chengcong, He, Xuying, Li, Xifeng, Duan, Chuanzhi

“…Mitochondrial dysfunction has been widely accepted as a detrimental factor in subarachnoid hemorrhage (SAH)-induced early brain injury (EBI), which is…”
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TSG-6 attenuates inflammation-induced brain injury via modulation of microglial polarization in SAH rats through the SOCS3/STAT3 pathway by Li, Ran, Liu, Wenchao, Yin, Jian, Chen, Yunchang, Guo, Shenquan, Fan, Haiyan, Li, Xifeng, Zhang, Xin, He, Xuying, Duan, Chuanzhi

“…An acute and drastic inflammatory response characterized by the production of inflammatory mediators is followed by stroke, including SAH. Overactivation of…”
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Early administration of multiple vasopressors is associated with better survival in patients with sepsis: a propensity score-weighted study by Tong, Xin, Xue, Xiaopeng, Duan, Chuanzhi, Liu, Aihua

“…The association between the timing of administration of multiple vasopressors and patient outcomes has not been investigated. This study used data from the…”
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Association between central venous pressure measurement and outcomes in critically ill patients with severe coma by Tong, Xin, Feng, Xin, Duan, Chuanzhi, Liu, Aihua

“…The use of central venous pressure (CVP) measurements among (intensive care unit) ICU patients with severe coma has been questioned. This study aimed to…”
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Tumor necrosis factor-stimulated gene-6 ameliorates early brain injury after subarachnoid hemorrhage by suppressing NLRC4 inflammasome-mediated astrocyte pyroptosis by Ding, Mingxiang, Jin, Lei, Wei, Boyang, Cheng, Wenping, Liu, Wenchao, Li, Xifeng, Duan, Chuanzhi

“…Subarachnoid hemorrhage is associated with high morbidity and mortality and lacks effective treatment. Pyroptosis is a crucial mechanism underlying early brain…”
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Mesenchymal stem cells alleviate the early brain injury of subarachnoid hemorrhage partly by suppression of Notch1-dependent neuroinflammation: involvement of Botch by Liu, Wenchao, Li, Ran, Yin, Jian, Guo, Shenquan, Chen, Yunchang, Fan, Haiyan, Li, Gancheng, Li, Zhenjun, Li, Xifeng, Zhang, Xin, He, Xuying, Duan, Chuanzhi

“…Activated microglia-mediated neuroinflammation has been regarded as an underlying key player in the pathogenesis of subarachnoid hemorrhage (SAH)-induced early…”
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Nrf-2 modulates excitability of hippocampal neurons by regulating ferroptosis and neuroinflammation after subarachnoid hemorrhage in rats by Fang, Dazhao, Guo, Shenquan, Wei, Boyang, Liu, Wenchao, Li, Guangxu, Li, Xifeng, Liu, Jiahui, Jin, Lei, Duan, Chuanzhi

“…Excitability of hippocampal neurons in subarachnoid hemorrhage (SAH) rats has not been well studied. The rat SAH model was applied in this study to explore the…”
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Prediction and analysis of periprocedural complications associated with endovascular treatment for unruptured intracranial aneurysms using machine learning by Tian, Zhongbin, Li, Wenqiang, Feng, Xin, Sun, Kaijian, Duan, Chuanzhi

“…Background The management of unruptured intracranial aneurysm (UIA) remains controversial. Recently, machine learning has been widely applied in the field of…”
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The inhibitory effect of mesenchymal stem cell on blood-brain barrier disruption following intracerebral hemorrhage in rats: contribution of TSG-6 by Chen, Min, Li, Xifeng, Zhang, Xin, He, Xuying, Lai, Lingfeng, Liu, Yanchao, Zhu, Guohui, Li, Wei, Li, Hui, Fang, Qinrui, Wang, Zequn, Duan, Chuanzhi

“…Mesenchymal stem cells (MSCs) are well known having beneficial effects on intracerebral hemorrhage (ICH) in previous studies. The therapeutic mechanisms are…”
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Silencing of SNHG12 Enhanced the Effectiveness of MSCs in Alleviating Ischemia/Reperfusion Injuries via the PI3K/AKT/mTOR Signaling Pathway by Li, Yuanzhi, Guo, Shenquan, Liu, Wenchao, Jin, Tao, Li, Xifeng, He, Xuying, Zhang, Xin, Su, Hengxian, Zhang, Nan, Duan, Chuanzhi

“…Previous studies have reported that the long non-coding RNA SNHG12 (lncRNA SNHG12) plays a critical role in regulating the function of mesenchymal stem cells…”
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CypD induced ROS output promotes intracranial aneurysm formation and rupture by 8-OHdG/NLRP3/MMP9 pathway by Fan, Haiyan, Tian, Hao, Jin, Fa, Zhang, Xin, Su, Shixing, Liu, Yanchao, Wen, Zhuohua, He, Xuying, Li, Xifeng, Duan, Chuanzhi

“…Reactive Oxygen Species (ROS) are widely accepted as a pernicious factor in the progression of intracranial aneurysm (IA), which is eminently related to cell…”
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Flow diversion treatment for giant intracranial serpentine aneurysms by Tong, Xin, He, Zijun, Han, Mingyang, Feng, Xin, Duan, Chuanzhi, Liu, Aihua

“…Background Giant serpentine aneurysms (GSAs) are among the most complex and challenging type of intracranial aneurysms. Surgical clipping, bypass, or…”
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Hepcidin depending on astrocytic NEO1 ameliorates blood-brain barrier dysfunction after subarachnoid hemorrhage by Wei, Boyang, Liu, Wenchao, Jin, Lei, Huang, Yaxian, Cheng, Wenping, Fan, Haiyan, Su, Shixing, Jin, Fa, Zhang, Xin, Yang, Zeyu, Liang, Shuyin, Li, Longxiang, Wu, Yu, Liu, Yanchao, Duan, Chuanzhi, Li, Xifeng

“…Subarachnoid hemorrhage (SAH) significantly compromises the blood-brain barrier (BBB) and impairs patient recovery. This study elucidates the critical role of…”
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Rupture discrimination of multiple small (< 7 mm) intracranial aneurysms based on machine learning-based cluster analysis by Tong, Xin, Feng, Xin, Peng, Fei, Niu, Hao, Zhang, Xin, Li, Xifeng, Zhao, Yuanli, Liu, Aihua, Duan, Chuanzhi

“…Small multiple intracranial aneurysms (SMIAs) are known to be more prone to rupture than are single aneurysms. However, specific recommendations for patients…”
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Adiponectin Ameliorates GMH-Induced Brain Injury by Regulating Microglia M1/M2 Polarization Via AdipoR1/APPL1/AMPK/PPARγ Signaling Pathway in Neonatal Rats by Xu, Ningbo, Li, Xifeng, Weng, Jun, Wei, Chunhua, He, Zhenyan, Doycheva, Desislava Met, Lenahan, Cameron, Tang, Wenhui, Zhou, Jian, Liu, Yanchao, Xu, Qiang, Liu, Yahong, He, Xuying, Tang, Jiping, Zhang, John H, Duan, Chuanzhi

“…Adiponectin (APN), a fat-derived plasma hormone, is a classic anti-inflammatory agent. Multiple studies have demonstrated the beneficial role of APN in acute…”
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Resolvin D1 ameliorates Inflammation-Mediated Blood-Brain Barrier Disruption After Subarachnoid Hemorrhage in rats by Modulating A20 and NLRP3 Inflammasome by Wei, Chengcong, Guo, Shenquan, Liu, Wenchao, Jin, Fa, Wei, Boyang, Fan, Haiyan, Su, Hengxian, Liu, Jiahui, Zhang, Nan, Fang, Dazhao, Li, Guangxu, Shu, Shixing, Li, Xifeng, He, Xuying, Zhang, Xin, Duan, Chuanzhi

“…Inflammation is typically related to dysfunction of the blood-brain barrier (BBB) that leads to early brain injury (EBI) after subarachnoid hemorrhage (SAH)…”
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Dexmedetomidine Inhibits Gasdermin D-Induced Pyroptosis via the PI3K/AKT/GSK3β Pathway to Attenuate Neuroinflammation in Early Brain Injury After Subarachnoid Hemorrhage in Rats by Wei, Boyang, Liu, Wenchao, Jin, Lei, Guo, Shenquan, Fan, Haiyan, Jin, Fa, Wei, Chengcong, Fang, Dazhao, Zhang, Xin, Su, Shixing, Duan, Chuanzhi, Li, Xifeng

“…Subarachnoid hemorrhage (SAH) is one kind of life-threatening stroke, which leads to severe brain damage. Pyroptosis plays a critical role in early brain…”
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Metformin Inhibits NLR Family Pyrin Domain Containing 3 (NLRP)-Relevant Neuroinflammation via an Adenosine-5'-Monophosphate-Activated Protein Kinase (AMPK)-Dependent Pathway to Alleviate Early Brain Injury After Subarachnoid Hemorrhage in Mice by Jin, Lei, Jin, Fa, Guo, Shenquan, Liu, Wenchao, Wei, Boyang, Fan, Haiyan, Li, Guangxu, Zhang, Xin, Su, Shixing, Li, Ran, Fang, Dazhao, Duan, Chuanzhi, Li, Xifeng

“…Neuroinflammation plays a key role in the pathogenesis of early brain injury (EBI) after subarachnoid hemorrhage (SAH). Previous studies have shown that…”
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Association Between Aneurysmal Hemodynamics and Rupture Risk of Unruptured Intracranial Aneurysms by Tian, Zhongbin, Li, Xifeng, Wang, Chao, Feng, Xin, Sun, Kaijian, Tu, Yi, Su, Hengxian, Yang, Xinjian, Duan, Chuanzhi

“…Assessing rupture risk in patients with unruptured intracranial aneurysms (UIAs) remains challenging. Hemodynamics plays an important role in the natural…”
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