Search Results - "Duan, Changzhu"

FDX1 can Impact the Prognosis and Mediate the Metabolism of Lung Adenocarcinoma by Zhang, Zeyu, Ma, Yarui, Guo, Xiaolei, Du, Yingxi, Zhu, Qing, Wang, Xiaobing, Duan, Changzhu

“…Background: Lung cancer has emerged as one of the most common cancers in recent years. The mitochondrial electron transport chain (ETC) is closely connected…”
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E3 ligase UHRF2 stabilizes the acetyltransferase TIP60 and regulates H3K9ac and H3K14ac via RING finger domain by Zeng, Shengyuan, Wang, Yangyang, Zhang, Ting, Bai, Lu, Wang, Yalan, Duan, Changzhu

“…UHRF2 is a ubiquitin-protein ligase E3 that regulates cell cycle, genomic stability and epigenetics, We conducted a co-immunoprecipitation assay and found that…”
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Phosphorylation of UHRF2 affects malignant phenotypes of HCC and HBV replication by blocking DHX9 ubiquitylation by Wu, Kejia, Zhang, Yiqi, Liu, Yuxin, Li, Qingxiu, Chen, Yong, Chen, Juan, Duan, Changzhu

“…Hepatitis B virus (HBV) infection is one of main contributors to poor prognosis and rapid progression of hepatocellular cancer (HCC). We previously identified…”
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HBx promotes hepatocarcinogenesis by enhancing phosphorylation and blocking ubiquitinylation of UHRF2 by Cheng, Fengjuan, Qian, Guanhua, Fang, Xianyun, Sun, Jingjie, Chen, Siyuan, Chen, Rongjuan, Liu, Shangjing, Li, Zhaodi, Wu, Kejia, Jiang, Shiming, Chen, Yong, Tang, Ni, Chen, Juan, Duan, Changzhu

“…Background and aims The major cause of Hepatocellular carcinoma (HCC) is acute or chronic infection caused by hepatotropic viruses and HBV infection is the…”
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NIRF, a novel ubiquitin ligase, interacts with hepatitis B virus core protein and promotes its degradation by Qian, Guanhua, Jin, Fangmin, Chang, Lei, Yang, Yan, Peng, Huimin, Duan, Changzhu

“…Hepatitis B virus (HBV) core protein (HBc) is a major component of viral nucleocapsid and a multifunctional protein involved in viral maturation and release…”
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Circular RNA MYLK as a competing endogenous RNA promotes bladder cancer progression through modulating VEGFA/VEGFR2 signaling pathway by Zhong, Zhenyu, Huang, Mengge, Lv, Mengxin, He, Yunfeng, Duan, Changzhu, Zhang, Luyu, Chen, Junxia

“…Accumulating evidences indicate that circular RNAs (circRNAs) play a vital role in modulating gene expression. However, the mechanisms underlying circRNAs…”
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UHRF2 promotes the malignancy of hepatocellular carcinoma by PARP1 mediated autophagy by Zhang, Yiqi, Wu, Kejia, Liu, Yuxin, Sun, Shuangling, Shao, Yue, Li, Qingxiu, Sui, Xinying, Duan, Changzhu

“…Autophagy have critical implications in the proliferation and metastasis of HCC. In the current study, we aimed to explore the underlying mechanisms of UHRF2…”
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SH2D4A inhibits esophageal squamous cell carcinoma progression through FAK/PI3K/AKT signaling pathway by Shi, Haoming, Luo, Jun, Ye, Liu, Duan, Changzhu, Zhang, Min, Ran, Haoyu, Li, Changying, Wu, Qingchen, Shao, Yue

“…Esophageal squamous cell carcinoma (ESCC), one of the most common malignant tumors, is now afflicting approximately 80% of patients diagnosed with esophageal…”
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Construction of HBV-HCC prognostic model and immune characteristics based on potential genes mining through protein interaction networks by Li, Qingxiu, Wu, Kejia, Zhang, Yiqi, Liu, Yuxin, Wang, Yalan, Chen, Yong, Sun, Shuangling, Duan, Changzhu

“…Objective To search for human protein-coding genes related to hepatocellular carcinoma (HCC) in the context of hepatitis B virus (HBV) infection, and perform…”
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Corrigendum to “Circular RNA MYLK as a competing endogenous RNA promotes bladder cancer progression through modulating VEGFA/VEGFR2 signaling pathway” [Cancer Letter 403(2017) 305–317] by Zhong, Zhenyu, Huang, Mengge, Lv, Mengxin, He, Yunfeng, Duan, Changzhu, Zhang, Luyu, Chen, Junxia

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Quantitative proteomics revealed the transition of ergosterol biosynthesis and drug transporters processes during the development of fungal fluconazole resistance by Sui, Xinying, Cheng, Xinyu, Li, Zhaodi, Wang, Yonghong, Zhang, Zhenpeng, Yan, Ruyue, Chang, Lei, Li, Yanchang, Xu, Ping, Duan, Changzhu

“…Fungal infections and antifungal resistance are the increasing global public health concerns. Mechanisms of fungal resistance include alterations in…”
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UHRF2 promotes Hepatocellular Carcinoma Progression by Upregulating ErbB3/Ras/Raf Signaling Pathway by Sun, Jingjie, Wu, Kejia, Chen, Siyuan, Jiang, Shiming, Chen, Yong, Duan, Changzhu

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Angiogenin interacts with ribonuclease inhibitor regulating PI3K/AKT/mTOR signaling pathway in bladder cancer cells by Peng, Yuan, Li, Lin, Huang, Mengge, Duan, Changzhu, Zhang, Luyu, Chen, Junxia

“…Angiogenin (ANG), a member of RNase A superfamily, is the only angiogenic factor that possesses ribonucleolytic activity. Recent studies showed that the…”
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Hepatitis B virus mutation pattern rtA181S+T184I+M204I may contribute to multidrug resistance in clinical practice: Analysis of a large cohort of Chinese patients by Chen, Rongjuan, Liu, Yan, Luo, Dan, Si, Lanlan, Huang, Bixia, Wang, Jun, Li, Xiaodong, Cheng, Fengjuan, Xu, Dongping, Duan, Changzhu

“…The study aimed to characterize the prevalence and virological features of the rtA181S + T184I + M204I mutant in a large cohort of patients with chronic HBV…”
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UHRF2 promotes DNA damage response by decreasing p21 via RING finger domain by Wang, Yangyang, Yan, Xinke, Zeng, Shengyuan, Zhang, Ting, Cheng, Fengjuan, Chen, Rongjuan, Duan, Changzhu

“…Objectives To investigate the interaction of E3 ubiquitin ligase UHRF2 with p21 and the mechanism of UHRF2 in repairing DNA damage caused by hydroxyurea (HU)…”
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UHRF2 decreases H3K9ac expression by interacting with it through the PHD and SRA/YDG domain in HepG2 hepatocellular carcinoma cells by Zhang, Ting, Zhao, Linglin, Zeng, Shengyuan, Bai, Lu, Chen, Junxia, Zhang, Zheng, Wang, Yalan, Duan, Changzhu

“…Ubiquitin-like with PHD and ring finger domains 2 (UHRF2) is a multi-domain E3 ubiquitin ligase which is involved in epigenetic regulation and plays an…”
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Let-7a elevates p21(WAF1) levels by targeting of NIRF and suppresses the growth of A549 lung cancer cells by He, Xiaoyan, Duan, Changzhu, Chen, Junxia, Ou-Yang, Xi, Zhang, Zheng, Li, Chunlei, Peng, Huimin

“…Down-regulation of let-7 microRNA (miRNA) is a key event in lung cancer. Despite recent advances in survival signaling, the roles of let-7 in the context of…”
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NIRF, a Novel Ubiquitin Ligase, Inhibits Hepatitis B Virus Replication Through Effect on HBV Core Protein and H3 Histones by Qian, Guanhua, Hu, Bin, Zhou, Danlin, Xuan, Yanyan, Bai, Lu, Duan, Changzhu

“…Np95/ICBP90-like RING finger protein (NIRF), a novel E3 ubiquitin ligase, has been shown to interact with HBc and promote its degradation. This study…”
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Retraction notice to “UHRF2, another E3 ubiquitin ligase for p53” [Biochem. Biophys. Res. Commun. 425 (2012) 908–911] by Bai, Lu, Wang, Xiaohui, Jin, Fangmin, Yang, Yan, Qian, Guanhua, Duan, Changzhu

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RETRACTED: UHRF2, another E3 ubiquitin ligase for p53 by Bai, Lu, Wang, Xiaohui, Jin, Fangmin, Yang, Yan, Qian, Guanhua, Duan, Changzhu

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