Search Results - "DuPont, Andrew"
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Safety and preliminary efficacy of orally administered lyophilized fecal microbiota product compared with frozen product given by enema for recurrent Clostridium difficile infection: A randomized clinical trial
Published in PloS one (02-11-2018)“…Fecal microbiota transplantation (FMT) via colonoscopy or enema has become a commonly used treatment of recurrent C. difficile infection (CDI). To compare the…”
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The intestinal microbiota and chronic disorders of the gut
Published in Nature reviews. Gastroenterology & hepatology (01-09-2011)“…The human gut supports a dense, diverse and dynamic bacterial ecosystem, which is important to intestinal health and disease. Quantitative and qualitative…”
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Systematic review of randomized controlled trials of probiotics, prebiotics, and synbiotics in inflammatory bowel disease
Published in Clinical and experimental gastroenterology (01-01-2014)“…Probiotics are microorganisms that are ingested either in combination or as a single organism in an effort to normalize intestinal microbiota and potentially…”
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S2118 Recurrent Clostridioides difficile Infections Caused by Topical Clindamycin
Published in The American journal of gastroenterology (01-10-2022)Get full text
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Mango (Mangifera indica L.) polyphenols reduce IL-8, GRO, and GM-SCF plasma levels and increase Lactobacillus species in a pilot study in patients with inflammatory bowel disease
Published in Nutrition research (New York, N.Y.) (01-03-2020)“…Inflammatory bowel disease (IBD) characterized by chronic intestinal inflammation and intestinal microbial dysbiosis present a major risk factor in the…”
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S2532 Fluoroquinolone-Induced Ischemic Colitis: A Case Series
Published in The American journal of gastroenterology (01-10-2023)Get full text
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Elevated transaminases and hypoalbuminemia in Covid-19 are prognostic factors for disease severity
Published in Scientific reports (13-05-2021)“…Prognostic markers are needed to understand the disease course and severity in patients with Covid-19. There is evidence that Covid-19 causes gastrointestinal…”
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Fecal microbiota transplantation in Parkinson's disease-A randomized repeat-dose, placebo-controlled clinical pilot study
Published in Frontiers in neurology (02-03-2023)“…The intestinal microbiome plays a primary role in the pathogenesis of neurodegenerative disorders and may provide an opportunity for disease modification. We…”
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Microbiota restoration therapies for recurrent Clostridioides difficile infection reach an important new milestone
Published in Therapeutic advances in gastroenterology (2024)“…Microbiota restoration therapy has become a standard treatment for recurrent infection (rCDI). In this article, we review the studies supporting the licensure…”
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Alterations in MAdCAM1-Positive Mucosal Capillaries and Integrin a4b7-Positive Lymphocytes in Crohn's Disease Treated with Anti-TNFα Biologics
Published in Annals of clinical and laboratory science (01-09-2021)“…To elucidate the reasons for the decreased effectiveness of Vedolizumab (VDZ) treatment in patients with Crohn's disease (CD) previously treated (CD-T) with…”
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Abnormal Intestinal Microbiome in Medical Disorders and Potential Reversibility by Fecal Microbiota Transplantation
Published in Digestive diseases and sciences (01-03-2020)“…Reduction in diversity of the intestinal microbiome (dysbiosis) is being identified in many disease states, and studies are showing important biologic…”
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Telomere dysfunction activates YAP1 to drive tissue inflammation
Published in Nature communications (21-09-2020)“…Germline telomere maintenance defects are associated with an increased incidence of inflammatory diseases in humans, yet whether and how telomere dysfunction…”
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Intestinal IgA-Coated Bacteria in Healthy- and Altered-Microbiomes (Dysbiosis) and Predictive Value in Successful Fecal Microbiota Transplantation
Published in Microorganisms (Basel) (29-12-2022)“…IgA-coated bacteria in the gut (IgA-biome) provide a homeostatic function in healthy people through inhibition of microbial invaders and by protecting the…”
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The Significance of So-Called Equivocal Immunohistochemical Staining for Cytomegalovirus in Colorectal Biopsies
Published in Archives of pathology & laboratory medicine (1976) (01-08-2019)“…Recent studies examining immunohistochemical staining of colorectal biopsies for cytomegalovirus (CMV) reported that some cases showed only occasional small…”
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The Quick Sepsis-Related Organ Failure Assessment Score Is Prognostic of Pancreatitis Severity in Patients With Alcohol-Induced Pancreatitis
Published in Pancreas (01-07-2022)Get full text
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Colonic Eosinophilia: Clinicopathologic Study of Paired Right and Left Colon Biopsies from 276 Patients
Published in Annals of clinical and laboratory science (01-01-2023)“…This study evaluated differences in eosinophil (Eos) count in the right colon (RC) and left colon (LC) relative to known clinical and pathologic features. H&E…”
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Anti-TNF-α Biologics Do Not Reverse CDX2 Downregulation in Patients with Crohn's Disease
Published in Annals of clinical and laboratory science (01-03-2020)“…The caudal-related homeobox transcription factor 2 (CDX2) plays an important role in intestinal epithelial differentiation, proliferation, migration, and…”
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In vivo analysis of mucosal lipids reveals histological disease activity in ulcerative colitis using endoscope-coupled Raman spectroscopy
Published in Biomedical optics express (01-07-2017)“…The goal of this study is to evaluate endoscopic Raman spectroscopy as a noninvasive technique to determine histological inflammatory status of colitis. Colon…”
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Effect of physiological factors on the biochemical properties of colon tissue – an in vivo Raman spectroscopy study
Published in Journal of Raman spectroscopy (01-07-2017)“…Raman spectroscopy provides diagnostic information by detecting disease‐associated subtle biochemical changes in the tissue. Yet the physiological variations…”
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