Search Results - "Du Yan, S"

LRP/Amyloid β-Peptide Interaction Mediates Differential Brain Efflux of Aβ Isoforms by Deane, Rashid, Wu, Zhenhua, Sagare, Abhay, Davis, Judianne, Du Yan, Shi, Hamm, Katie, Xu, Feng, Parisi, Margaret, LaRue, Barbra, Hu, Hong Wei, Spijkers, Patricia, Guo, Huang, Song, Xiaomei, Lenting, Peter J., Van Nostrand, William E., Zlokovic, Berislav V.

“…LRP (low-density lipoprotein receptor-related protein) is linked to Alzheimer's disease (AD). Here, we report amyloid β-peptide Aβ40 binds to immobilized LRP…”
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The multiligand receptor RAGE as a progression factor amplifying immune and inflammatory responses by Schmidt, A M, Yan, S D, Yan, S F, Stern, D M

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Receptor for advanced glycation end products (RAGE) regulates sepsis but not the adaptive immune response by Liliensiek, Birgit, Weigand, Markus A, Bierhaus, Angelika, Nicklas, Werner, Kasper, Michael, Hofer, Stefan, Plachky, Jens, Gröne, Herman-Josef, Kurschus, Florian C, Schmidt, Ann Marie, Yan, Shi Du, Martin, Eike, Schleicher, Erwin, Stern, David M, Hämmerling G, G ünterJ, Nawroth, Peter P, Arnold, Bernd

“…While the initiation of the adaptive and innate immune response is well understood, less is known about cellular mechanisms propagating inflammation. The…”
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N(epsilon)-(carboxymethyl)lysine adducts of proteins are ligands for receptor for advanced glycation end products that activate cell signaling pathways and modulate gene expression by Kislinger, T, Fu, C, Huber, B, Qu, W, Taguchi, A, Du Yan, S, Hofmann, M, Yan, S F, Pischetsrieder, M, Stern, D, Schmidt, A M

“…Recent studies suggested that interruption of the interaction of advanced glycation end products (AGEs), with the signal-transducing receptor receptor for AGE…”
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Central role of RAGE-dependent neointimal expansion in arterial restenosis by Sakaguchi, Taichi, Yan, Shi Fang, Yan, Shi Du, Belov, Dmitri, Rong, Ling Ling, Sousa, Monica, Andrassy, Martin, Marso, Steven P, Duda, Stephan, Arnold, Bernd, Liliensiek, Birgit, Nawroth, Peter P, Stern, David M, Schmidt, Ann Marie, Naka, Yoshifumi

“…Cellular proliferation, migration, and expression of extracellular matrix proteins and MMPs contribute to neointimal formation upon vascular injury. Wild-type…”
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Involvement of Microglial Receptor for Advanced Glycation Endproducts (RAGE) in Alzheimer's Disease: Identification of a Cellular Activation Mechanism by Lue, Lih-Fen, Walker, Douglas G., Brachova, Libuse, Beach, Thomas G., Rogers, Joseph, Schmidt, Ann Marie, Stern, David M., Yan, Shi Du

“…Receptor-mediated interactions with amyloid β-peptide (Aβ) could be important in the evolution of the inflammatory processes and cellular dysfunction that are…”
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Receptor for advanced glycation endproducts (RAGE) and the complications of diabetes by Stern, David M, Yan, Shi Du, Yan, Shi Fang, Schmidt, Ann Marie

“…Receptor for Advanced Glycation Endproducts (RAGE) is a multiligand member of the immunoglobulin superfamily of cell surface molecules with a diverse…”
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Familial Amyloid Polyneuropathy: Receptor for Advanced Glycation End Products-Dependent Triggering of Neuronal Inflammatory and Apoptotic Pathways by Sousa, Monica Mendes, Du Yan, Shi, Fernandes, Rui, Guimaraes, Antonio, Stern, David, Saraiva, Maria Joao

“…Familial amyloid polyneuropathy (FAP) is a neurodegenerative disorder associated with extracellular deposition of mutant transthyretin (TTR) amyloid fibrils,…”
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beta-amyloid-induced migration of monocytes across human brain endothelial cells involves RAGE and PECAM-1 by Giri, R, Shen, Y, Stins, M, Du Yan, S, Schmidt, A M, Stern, D, Kim, K S, Zlokovic, B, Kalra, V K

“…In patients with amyloid beta-related cerebrovascular disorders, e.g. , Alzheimer's disease, one finds increased deposition of amyloid peptide (Abeta) and…”
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Antagonism of RAGE suppresses peripheral nerve regeneration by Rong, Ling Ling, Trojaborg, Werner, Qu, Wu, Kostov, Konstantin, Yan, Shi Du, Gooch, Clifton, Szabolcs, Matthias, Hays, Arthur P., Schmidt, Ann Marie

“…Axotomy of peripheral nerve triggers events that coordinate a limited inflammatory response to axonal degeneration and initiation of neurite outgrowth…”
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Amyloid-β Peptide-Receptor for Advanced Glycation Endproduct Interaction Elicits Neuronal Expression of Macrophage-Colony Stimulating Factor: A Proinflammatory Pathway in Alzheimer Disease by Du Yan, Shi, Zhu, Huaijie, Fu, Jin, Yan, Shi Fang, Roher, Alex, Tourtellotte, Wallace W., Rajavashisth, Tripathi, Chen, Xi, Godman, Gabriel C., Stern, David, Schmidt, Ann Marie

“…In Alzheimer disease (AD), neurons are thought to be subjected to the deleterious cytotoxic effects of activated microglia. We demonstrate that binding of…”
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Interaction of the Receptor for Advanced Glycation End Products (RAGE) with Transthyretin Triggers Nuclear Transcription Factor kB (NF-kB) Activation by MENDES SOUSA, M, SHI DU YAN, STERN, D, JOAO SARAIVA, M

“…Mutated transthyretin (TTR) fibrils are associated with the pathology of familial amyloidotic polyneuropathy (FAP), in which extracellular amyloid deposits…”
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Regional cerebral blood volume reduction in transgenic mutant APP (V717F, K670N/M671L) mice by Wu, Ed X, Tang, Haiying, Asai, Tomohiro, Yan, Shi Du

“…Recent advance in nuclear magnetic resonance (NMR) microimaging has enabled in vivo cerebral blood volume (CBV) mapping with high spatial resolution. Using an…”
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L-3-hydroxyacyl-CoA dehydrogenase II protects in a model of Parkinson's disease by Tieu, Kim, Perier, Celine, Vila, Miquel, Caspersen, Casper, Zhang, Hui-Ping, Teismann, Peter, Jackson-Lewis, Vernice, Stern, David M., Yan, Shi Du, Przedborski, Serge

“…The neurotoxin 1‐methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine (MPTP) impairs mitochondrial respiration and damages dopaminergic neurons as seen in Parkinson's…”
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RAGE potentiates Aβ-induced perturbation of neuronal function in transgenic mice by Arancio, Ottavio, Zhang, Hui Ping, Chen, Xi, Lin, Chang, Trinchese, Fabrizio, Puzzo, Daniela, Liu, Shumin, Hegde, Ashok, Yan, Shi Fang, Stern, Alan, Luddy, John S, Lue, Lih-Fen, Walker, Douglas G, Roher, Alex, Buttini, Manuel, Mucke, Lennart, Li, Weiying, Schmidt, Ann Marie, Kindy, Mark, Hyslop, Paul A, Stern, David M, Du Yan, Shirley Shi

“…Receptor for Advanced Glycation Endproducts (RAGE), a multiligand receptor in the immunoglobulin superfamily, functions as a signal‐transducing cell surface…”
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RAGE: a multiligand receptor contributing to the cellular response in diabetic vasculopathy and inflammation by Schmidt, A M, Hofmann, M, Taguchi, A, Yan, S D, Stern, D M

“…RAGE is a multiligand member of the immunoglobulin superfamily of cell surface molecules whose properties extend the paradigm of ligand-receptor interactions…”
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Role of ERAB/l-3-Hydroxyacyl-coenzyme A Dehydrogenase Type II Activity in Aβ-induced Cytotoxicity by Du Yan, Shi, Shi, Yigong, Zhu, Aiping, Fu, Jin, Zhu, Huaijie, Zhu, Yucui, Gibson, Lenneen, Stern, Eric, Collison, Kate, Al-Mohanna, Futwan, Ogawa, Satoshi, Roher, Alex, Clarke, Steven G., Stern, David M.

“…Endoplasmic reticulum-associated amyloid β-peptide (Aβ)-binding protein (ERAB)/l-3-hydroxyacyl-CoA dehydrogenase type II (HADH II) is expressed at high levels…”
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Glycation and diabetes: The RAGE connection by Hudson, Barry I., Hofmann, Marion A., Bucciarelli, Loredana, Wendt, Thoralf, Moser, Bernhard, Lu, Yan, Qu, Wu, Stern, David M., D'Agati, Vivette, Du Yan, Shi, Yan, Shi Fang, Grant, Peter J., Schmidt, Ann Marie

“…The hyperglycaemic state seen in diabetes mellitus is associated with the development of diabetes-specific microvascular complications and accelerated…”
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Amyloid beta -peptide-binding alcohol dehydrogenase is a component of the cellular response to nutritional stress by Du Yan, S, Zhu, Y, Stern, E D, Hwang, Y C, Hori, O, Ogawa, S, Frosch, M P, Connolly, Jr, E S, McTaggert, R, Pinsky, D J, Clarke, S, Stern, D M, Ramasamy, R

“…Amyloid beta-peptide-binding alcohol dehydrogenase (ABAD) is a member of the family of short chain dehydrogenase/reductases whose distinctive properties…”
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Expression of Egr-1 in Late Stage Emphysema by Zhang, Weisu, Yan, Shi Du, Zhu, Aiping, Zou, Yu Shan, Williams, Matthew, Godman, Gabriel C., Thomashow, Byron M., Ginsburg, Mark E., Stern, David M., Yan, Shi-Fang

“…The transcription factor early growth response (Egr)-1 is an immediate-early gene product rapidly and transiently expressed after acute tissue injury. In…”
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