Search Results - "Du Plessis, Jeanetta"

Sinigrin and Its Therapeutic Benefits by Mazumder, Anisha, Dwivedi, Anupma, du Plessis, Jeanetta

“…Sinigrin (allyl-glucosinolate or 2-propenyl-glucosinolate) is a natural aliphatic glucosinolate present in plants of the Brassicaceae family, such as broccoli…”
Get full text

Review of natural compounds for potential skin cancer treatment by Chinembiri, Tawona N, du Plessis, Lissinda H, Gerber, Minja, Hamman, Josias H, du Plessis, Jeanetta

“…Most anti-cancer drugs are derived from natural resources such as marine, microbial and botanical sources. Cutaneous malignant melanoma is the most aggressive…”
Get full text

Transdermal Drug Delivery Enhancement by Compounds of Natural Origin by Fox, Lizelle T., Gerber, Minja, Plessis, Jeanetta Du, Hamman, Josias H.

“…The transdermal route of administration offers an alternative pathway for systemic drug delivery with numerous advantages over conventional routes…”
Get full text

Treatment Modalities for Acne by Fox, Lizelle, Csongradi, Candice, Aucamp, Marique, du Plessis, Jeanetta, Gerber, Minja

“…Acne is a common inflammatory skin disease which affects the pilosebaceous units of the skin. It can have severe psychological effects and can leave the…”
Get full text

In vitro wound healing and cytotoxic effects of sinigrin–phytosome complex by Mazumder, Anisha, Dwivedi, Anupma, du Preez, Jan L., du Plessis, Jeanetta

“…[Display omitted] Sinigrin is a class of glucosinolates found naturally in plants of the Brassicaceae family. Lately, studies have shown that sinigrin…”
Get full text

Breaching the skin barrier through temperature modulations by Shahzad, Yasser, Louw, Ruaan, Gerber, Minja, du Plessis, Jeanetta

“…The impermeability of the stratum corneum often hinders the transport of molecules across the skin. Temperature modulations in the skin and the application of…”
Get full text

Development of a Self-Emulsifying Drug Delivery System for Optimized Topical Delivery of Clofazimine by van Staden, Daniélle, du Plessis, Jeanetta, Viljoen, Joe

“…A quality-by-design and characterization approach was followed to ensure development of self-emulsifying drug delivery systems (SEDDSs) destined for topical…”
Get full text

Formulation of Natural Oil Nano-Emulsions for the Topical Delivery of Clofazimine, Artemisone and Decoquinate by Burger, Cornel, Aucamp, Marique, du Preez, Jan, Haynes, Richard K., Ngwane, Andile, du Plessis, Jeanetta, Gerber, Minja

“…Purpose The aim of this study was to formulate nano-emulsions comprising natural oils and the active pharmaceutical ingredients (APIs) clofazimine (CLF),…”
Get full text

Development of Topical/Transdermal Self-Emulsifying Drug Delivery Systems, Not as Simple as Expected by van Staden, Danielle, du Plessis, Jeanetta, Viljoen, Joe

“…Self-emulsifying drug delivery systems (SEDDSs) originated as an oral lipid-based drug delivery system with the sole purpose of improving delivery of highly…”
Get full text

In vitro anti-cancer effects of artemisone nano-vesicular formulations on melanoma cells by Dwivedi, Anupma, PhD, Mazumder, Anisha, PhD, du Plessis, Lissinda, PhD, du Preez, Jan L., PhD, Haynes, Richard K., PhD, du Plessis, Jeanetta, PhD

“…Abstract Artemisone is a 10-amino-artemisinin derivative that is markedly superior in vitro and in vivo to current artemisinins against malaria and also…”
Get full text

Whey Protein/Polysaccharide-Stabilized Emulsions: Effect of Polymer Type and pH on Release and Topical Delivery of Salicylic Acid by Combrinck, Johann, Otto, Anja, du Plessis, Jeanetta

“…Emulsions are widely used as topical formulations in the pharmaceutical and cosmetic industries. They are thermodynamically unstable and require emulsifiers…”
Get full text

The selection of non-steroidal anti-inflammatory agents for dermal delivery by Hadgraft, Jonathan, Plessis, Jeanetta du, Goosen, Colleen

“…An analysis has been conducted to show how the penetration of a selection of non-steroidal anti-inflammatory agents (NSAIDs) through the skin may be predicted…”
Get full text

Topical Delivery of 5-Fluorouracil from Pheroid™ Formulations and the In Vitro Efficacy Against Human Melanoma by Chinembiri, Tawona N., Gerber, Minja, du Plessis, Lissinda, du Preez, Jan, du Plessis, Jeanetta

“…Drug delivery vehicles can influence the topical delivery and the efficacy of an active pharmaceutical ingredient (API). In this study, the influence of…”
Get full text

Vesicular carriers for skin drug delivery: the Pheroid™ technology by Kilian, Dewald, Shahzad, Yasser, Fox, Lizelle, Gerber, Minja, Du Plessis, Jeanetta

“…The skin remains an attractive area for drug delivery. The skin, however, often limits the ingress of drugs, because of its very low permeability. Much…”
Get more information

Traversing the Skin Barrier with Nano-emulsions by Burger, Cornel, Shahzad, Yasser, Brummer, Alicia, Gerber, Minja, du Plessis, Jeanetta

“…In recent years, colloidal delivery systems based on nano-emulsion are gaining popularity; being used for encapsulation and delivery of many drugs. This review…”
Get more information

Skin permeation enhancement effects of the gel and whole-leaf materials of Aloe vera, Aloe marlothii and Aloe ferox by Fox, Lizelle T., Gerber, Minja, Preez, Jan L. du, Plessis, Jeanetta du, Hamman, Josias H.

“…Objectives The aim of this study was to investigate the in‐vitro permeation enhancement effects of the gel and whole‐leaf materials of Aloe vera, Aloe…”
Get full text

Physicochemical characterization and solubility analysis of thalidomide and its N-alkyl analogs by GOOSEN, Colleen, LAING, Timothy J, PLESSIS, Jeanetta Du, GOOSEN, Theunis C, FLYNN, Gordon L

“…The present study was primarily aimed at exploring the feasibility of improving percutaneous delivery via chemical manipulation of the thalidomide molecule to…”
Get full text

Bioactive albumin-based carriers for tumour chemotherapy by Shahzad, Yasser, Khan, Ikram Ullah, Hussain, Talib, Alamgeer, Serra, Christophe A, Rizvi, Syed A A, Gerber, Minja, du Plessis, Jeanetta

“…Proteins are posed as the natural counterpart of the synthetic polymers for the development of drug delivery systems and few of them, have been regarded safe…”
Get more information

Transport of aspalathin, a Rooibos tea flavonoid, across the skin and intestinal epithelium by Huang, Miao, du Plessis, Jeanetta, du Preez, Jan, Hamman, Josias, Viljoen, Alvaro

“…Since Rooibos tea contains high levels of flavonoid antioxidants with potential health benefits when taken orally or applied topically, the quantity of the…”
Get full text

Synthesis and transdermal penetration of NSAID glycoside esters by Swart, Henk, Breytenbach, Jaco C., Hadgraft, Jonathan, Plessis, Jeanetta du

“…The glucoside and mannoside derivatives of the NSAIDs flurbiprofen, ibuprofen, ketoprofen and naproxen were synthesised and their penetration through human…”
Get full text