Search Results - "Du Pasquier, Renaud"

Type I Interferon Inhibits Interleukin-1 Production and Inflammasome Activation by Guarda, Greta, Braun, Marion, Staehli, Francesco, Tardivel, Aubry, Mattmann, Chantal, Förster, Irmgard, Farlik, Matthias, Decker, Thomas, Du Pasquier, Renaud A., Romero, Pedro, Tschopp, Jürg

“…Type I interferon (IFN) is a common therapy for autoimmune and inflammatory disorders, yet the mechanisms of action are largely unknown. Here we showed that…”
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Intrinsic blood-brain barrier dysfunction contributes to multiple sclerosis pathogenesis by Nishihara, Hideaki, Perriot, Sylvain, Gastfriend, Benjamin D, Steinfort, Marel, Cibien, Celine, Soldati, Sasha, Matsuo, Kinya, Guimbal, Sarah, Mathias, Amandine, Palecek, Sean P, Shusta, Eric V, Pasquier, Renaud Du, Engelhardt, Britta

“…Blood-brain barrier (BBB) breakdown and immune cell infiltration into the CNS are early hallmarks of multiple sclerosis (MS). The mechanisms leading to BBB…”
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Human Induced Pluripotent Stem Cell-Derived Astrocytes Are Differentially Activated by Multiple Sclerosis-Associated Cytokines by Perriot, Sylvain, Mathias, Amandine, Perriard, Guillaume, Canales, Mathieu, Jonkmans, Nils, Merienne, Nicolas, Meunier, Cécile, El Kassar, Lina, Perrier, Anselme L., Laplaud, David-Axel, Schluep, Myriam, Déglon, Nicole, Du Pasquier, Renaud

“…Recent studies highlighted the importance of astrocytes in neuroinflammatory diseases, interacting closely with other CNS cells but also with the immune…”
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Immune responses to JC virus in patients with multiple sclerosis treated with natalizumab: a cross-sectional and longitudinal study by Jilek, Samantha, PhD, Jaquiéry, Emilie, MSc, Hirsch, Hans H, MD, Lysandropoulos, Andreas, MD, Canales, Mathieu, Guignard, Laurence, Schluep, Myriam, MD, Pantaleo, Giuseppe, MD, Du Pasquier, Renaud A, MD

“…Summary Background Natalizumab is used to prevent relapses and progression of disability in patients with multiple sclerosis but has been associated with…”
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Elevated Tribbles homolog 2-specific antibody levels in narcolepsy patients by Cvetkovic-Lopes, Vesna, Bayer, Laurence, Dorsaz, Stéphane, Maret, Stéphanie, Pradervand, Sylvain, Dauvilliers, Yves, Lecendreux, Michel, Lammers, Gert-Jan, Donjacour, Claire E H M, Du Pasquier, Renaud A, Pfister, Corinne, Petit, Brice, Hor, Hyun, Mühlethaler, Michel, Tafti, Mehdi

“…Narcolepsy is a sleep disorder characterized by excessive daytime sleepiness and attacks of muscle atonia triggered by strong emotions (cataplexy). Narcolepsy…”
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Interleukin-22 is increased in multiple sclerosis patients and targets astrocytes by Perriard, Guillaume, Mathias, Amandine, Enz, Lukas, Canales, Mathieu, Schluep, Myriam, Gentner, Melanie, Schaeren-Wiemers, Nicole, Du Pasquier, Renaud A

“…Increasing evidences link T helper 17 (Th17) cells with multiple sclerosis (MS). In this context, interleukin-22 (IL-22), a Th17-linked cytokine, has been…”
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Micro-structural brain alterations in aviremic HIV+ patients with minor neurocognitive disorders: a multi-contrast study at high field by Granziera, Cristina, Daducci, Alessandro, Simioni, Samanta, Cavassini, Matthias, Roche, Alexis, Meskaldji, Djalel, Kober, Tobias, Metral, Melanie, Calmy, Alexandra, Helms, Gunther, Hirschel, Bernard, Lazeyras, François, Meuli, Reto, Krueger, Gunnar, Du Pasquier, Renaud A

“…Mild neurocognitive disorders (MND) affect a subset of HIV+ patients under effective combination antiretroviral therapy (cART). In this study, we used an…”
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Multiple sclerosis decreases explicit counterfactual processing and risk taking in decision making by Simioni, Samanta, Schluep, Myriam, Bault, Nadège, Coricelli, Giorgio, Kleeberg, Joerg, Du Pasquier, Renaud A, Gschwind, Markus, Vuilleumier, Patrik, Annoni, Jean-Marie

“…Deficits in decision making (DM) are commonly associated with prefrontal cortical damage, but may occur with multiple sclerosis (MS). There are no data…”
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CCR5 Blockade in Inflammatory PML and PML-IRIS Associated With Chronic Inflammatory Diseases' Treatments by Bernard-Valnet, Raphael, Moisset, Xavier, Maubeuge, Nicolas, Lefebvre, Mathilde, Ouallet, Jean-Christophe, Roumier, Mathilde, Lebrun-Frenay, Christine, Ciron, Jonathan, Biotti, Damien, Clavelou, Pierre, Godeau, Bertrand, Du Pasquier, Renaud A., Martin-Blondel, Guillaume

“…Progressive multifocal leukoencephalopathy (PML) is a disabling neurologic disorder resulting from the infection of the CNS by JC polyomavirus in…”
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The Combined Quantification and Interpretation of Multiple Quantitative Magnetic Resonance Imaging Metrics Enlightens Longitudinal Changes Compatible with Brain Repair in Relapsing-Remitting Multiple Sclerosis Patients by Bonnier, Guillaume, Maréchal, Benedicte, Fartaria, Mário João, Falkowskiy, Pavel, Marques, José P, Simioni, Samanta, Schluep, Myriam, Du Pasquier, Renaud, Thiran, Jean-Philippe, Krueger, Gunnar, Granziera, Cristina

“…Quantitative and semi-quantitative MRI (qMRI) metrics provide complementary specificity and differential sensitivity to pathological brain changes compatible…”
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Immunological Mechanism of Action and Clinical Profile of Disease-Modifying Treatments in Multiple Sclerosis by Du Pasquier, Renaud A., Pinschewer, Daniel D., Merkler, Doron

“…Multiple sclerosis (MS) is a life-long, potentially debilitating disease of the central nervous system (CNS). MS is considered to be an immune-mediated…”
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HIV testing practices by clinical service before and after revised testing guidelines in a Swiss University Hospital by Darling, Katharine E A, Hugli, Olivier, Mamin, Rachel, Cellerai, Cristina, Martenet, Sebastien, Berney, Alexandre, Peters, Solange, Du Pasquier, Renaud A, Bodenmann, Patrick, Cavassini, Matthias

“…To determine 1) HIV testing practices in a 1400-bed university hospital where local HIV prevalence is 0.4% and 2) the effect on testing practices of national…”
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Pattern of cognitive deficits in severe COVID-19 by Beaud, Valérie, Crottaz-Herbette, Sonia, Dunet, Vincent, Vaucher, Julien, Bernard-Valnet, Raphaël, Du Pasquier, Renaud, Bart, Pierre-Alexandre, Clarke, Stephanie

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Multicontrast MRI Quantification of Focal Inflammation and Degeneration in Multiple Sclerosis by Schluep, Myriam, Sumpf, Tilman Johannes, Frahm, Jens, Thiran, Jean-Philippe, Krueger, Gunnar, Granziera, Cristina, Menegaz, Gloria, Lin, Ying-Chia, Rotzinger, David, Meskaldji, Djalel Eddine, Simioni, Samanta, Romascano, David, Roche, Alexis, Bonnier, Guillaume, Du Pasquier, R.

“…Introduction. Local microstructural pathology in multiple sclerosis patients might influence their clinical performance. This study applied multicontrast MRI…”
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Advances in Treatment of Progressive Multifocal Leukoencephalopathy by Bernard‐Valnet, Raphaël, Koralnik, Igor J., Du Pasquier, Renaud

“…Progressive multifocal encephalopathy (PML) is a severe demyelinating disease of the central nervous system (CNS) caused by JC virus (JCV), which occurs in…”
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Paramagnetic Rim Lesions are Specific to Multiple Sclerosis: An International Multicenter 3T MRI Study by Maggi, Pietro, Sati, Pascal, Nair, Govind, Cortese, Irene C. M., Jacobson, Steven, Smith, Bryan R., Nath, Avindra, Ohayon, Joan, Pesch, Vincent, Perrotta, Gaetano, Pot, Caroline, Théaudin, Marie, Martinelli, Vittorio, Scotti, Roberta, Wu, Tianxia, Du Pasquier, Renaud, Calabresi, Peter A., Filippi, Massimo, Reich, Daniel S., Absinta, Martina

“…In multiple sclerosis (MS), a subset of chronic active white matter lesions are identifiable on magnetic resonance imaging by their paramagnetic rims, and…”
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Interplay of Cellular and Humoral Immune Responses against BK Virus in Kidney Transplant Recipients with Polyomavirus Nephropathy by YIPING CHEN, TROFE, Jennifer, GORDON, Jennifer, DU PASQUIER, Renaud A, ROY-CHAUDHURY, Prabir, KURODA, Marcelo J, WOODLE, E. Steve, KHALILI, Kamel, KORALNIK, Igor J

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Inflammatory Reaction in Progressive Multifocal Leukoencephalopathy: Harmful or Beneficial? by Pasquier, Renaud A Du, Koralnik, Igor J

“…Progressive multifocal leukoencephalopathy (PML) occurs in patients with profound immunosuppression. Although lesions are usually devoid of lymphoplasmocytic…”
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Status epilepticus of inflammatory etiology: A cohort study by Spatola, Marianna, Novy, Jan, Du Pasquier, Renaud, Dalmau, Josep, Rossetti, Andrea O

“…OBJECTIVE:Inflammation-related epilepsy is increasingly recognized; however, studies on status epilepticus (SE) are very infrequent. We therefore aimed to…”
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Motor behavior unmasks residual cognition in disorders of consciousness by Pincherle, Alessandro, Jöhr, Jane, Chatelle, Camille, Pignat, Jean‐Michel, Du Pasquier, Renaud, Ryvlin, Philippe, Oddo, Mauro, Diserens, Karin

“…Disorders of consciousness (DOC) are a common consequence of severe brain injuries, and clinical evaluation is critical to provide a correct diagnosis and…”
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