Search Results - "Dünnhaupt, Sarah"

Preactivated thiomers as mucoadhesive polymers for drug delivery by Iqbal, Javed, Shahnaz, Gul, Dünnhaupt, Sarah, Müller, Christiane, Hintzen, Fabian, Bernkop-Schnürch, Andreas

“…Abstract This study was aimed to synthesize polymeric excipients with improved mucoadhesive, cohesive and in situ-gelling properties to assure a prolonged…”
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S-Protected Thiolated Chitosan for Oral Delivery of Hydrophilic Macromolecules: Evaluation of Permeation Enhancing and Efflux Pump Inhibitory Properties by Dünnhaupt, Sarah, Barthelmes, Jan, Rahmat, Deni, Leithner, Katharina, Thurner, Clemens C, Friedl, Heike, Bernkop-Schnürch, Andreas

“…The objective of this study was the investigation of permeation enhancing and P-glycoprotein (P-gp) inhibition effects of a novel thiolated chitosan, the…”
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Synthesis and In Vitro Characterization of a Preactivated Thiomer via Polymerization Reaction by Solhi, Laleh, Schönbichler, Stefan A, Dünnhaupt, Sarah, Barthelmes, Jan, Friedl, Heike, Huck, Christian W, Bernkop-Schnürch, Andreas

“…The objective of this study was to synthesize 6-(2-acryloylamino-ethyldisulfanyl)-nicotinic acid (ACENA) for subsequent copolymerization with acrylic acid (AA)…”
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Chitosan-based drug delivery systems by Bernkop-Schnürch, Andreas, Dünnhaupt, Sarah

“…■■■ Within the past 20years, a considerable amount of work has been published on chitosan and its potential use in drug delivery systems. In contrast to all…”
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Development and evaluation of a novel mucus diffusion test system approved by self-nanoemulsifying drug delivery systems by Friedl, Heike, Dünnhaupt, Sarah, Hintzen, Fabian, Waldner, Claudia, Parikh, Shruti, Pearson, Jeffrey P, Wilcox, Matthew D, Bernkop-Schnürch, Andreas

“…The aim of this study was the development of a novel mucus diffusion model and the approval thereof by self-nanoemulsifying drug delivery systems (SNEDDSs)…”
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Mucoadhesive hydrogels for buccal drug delivery: In vitro-in vivo correlation study by Baus, Randi Angela, Zahir-Jouzdani, Forouhe, Dünnhaupt, Sarah, Atyabi, Fatemeh, Bernkop-Schnürch, Andreas

“…[Display omitted] It was the aim of this study to assess in vitro methods for the characterization of mucoadhesive hydrogels for their potential to predict the…”
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Thiolated particles as effective intravesical drug delivery systems for treatment of bladder-related diseases by Barthelmes, Jan, Dünnhaupt, Sarah, Unterhofer, Sibylle, Perera, Glen, Schlocker, Wolfgang, Bernkop-Schnürch, Andreas

“…To prove in vivo mucoadhesiveness of thiolated and well-established polymeric microparticles and nanoparticles (NPs) as a promising nanomedical tool for the…”
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Combining two technologies: Multifunctional polymers and self-nanoemulsifying drug delivery system (SNEDDS) for oral insulin administration by Sakloetsakun, Duangkamon, Dünnhaupt, Sarah, Barthelmes, Jan, Perera, Glen, Bernkop-Schnürch, Andreas

“…The aim of the study is to develop a self-nanoemulsifying drug delivery system (SNEDDS) based on thiolated chitosan for oral insulin administration. The…”
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Development of a mucoadhesive nanoparticulate drug delivery system for a targeted drug release in the bladder by Barthelmes, Jan, Perera, Glen, Hombach, Juliane, Dünnhaupt, Sarah, Bernkop-Schnürch, Andreas

“…Purpose of the present study was the development of a mucoadhesive nanoparticulate drug delivery system for local use in intravesical therapy of interstitial…”
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Distribution of thiolated mucoadhesive nanoparticles on intestinal mucosa by Dünnhaupt, Sarah, Barthelmes, Jan, Hombach, Juliane, Sakloetsakun, Duangkamon, Arkhipova, Valeriya, Bernkop-Schnürch, Andreas

“…It was the aim of the present study to evaluate and compare the distribution of thiolated mucoadhesive anionic poly(acrylic acid) (PAA) and cationic chitosan…”
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Methods to determine the interactions of micro- and nanoparticles with mucus by Grießinger, Julia, Dünnhaupt, Sarah, Cattoz, Beatrice, Griffiths, Peter, Oh, Sejin, Gómez, Salvador Borrós i, Wilcox, Matthew, Pearson, Jeffrey, Gumbleton, Mark, Abdulkarim, Muthanna, Pereira de Sousa, Irene, Bernkop-Schnürch, Andreas

“…[Display omitted] •Methods to examine the interactions between mucus layer and nanocarriers were depicted.•Methods to analyze particle diffusion in mucus were…”
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Preactivated thiomers for vaginal drug delivery vehicles by Friedl, Heike E, Dünnhaupt, Sarah, Waldner, Claudia, Bernkop-Schnürch, Andreas

“…Abstract It was the purpose of this study to design and evaluate a chitosan derivative as mucoadhesive excipient for vaginal drug delivery systems. The…”
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Nanoparticular delivery system for a secretoneurin derivative induces angiogenesis in a hind limb ischemia model by Albrecht-Schgoer, Karin, Barthelmes, Jan, Schgoer, Wilfried, Theurl, Markus, Nardin, Isabelle, Lener, Daniela, Gutmann, Clemens, Dünnhaupt, Sarah, Bernkop-Schnürch, Andreas, Kirchmair, Rudolf

“…Common therapeutic strategies for peripheral arterial disease often fail to re-establish sufficient blood flow within legs and feet of patients for avoiding…”
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S-protected thiolated chitosan: Synthesis and in vitro characterization by Dünnhaupt, Sarah, Barthelmes, Jan, Thurner, Clemens C., Waldner, Claudia, Sakloetsakun, Duangkamon, Bernkop-Schnürch, Andreas

“…► Synthesis of a novel mucoadhesive thiolated chitosan with protected thiol groups. ► The novel conjugate exhibited promising mucoadhesive features. ► In vitro…”
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Chitosan-based drug delivery systems by BERNKOP-SCHNÜRCH, Andreas, DÜNNHAUPT, Sarah

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Preactivated thiomers: Evaluation of gastroretentive minitablets by Hauptstein, Sabine, Müller, Christiane, Dünnhaupt, Sarah, Laffleur, Flavia, Bernkop-Schnürch, Andreas

“…The object of this study was to evaluate the potential of a recently developed preactivated thiolated pectin derivative as mucoadhesive excipient in drug…”
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In vivo evaluation of an oral drug delivery system for peptides based on S-protected thiolated chitosan by Dünnhaupt, Sarah, Barthelmes, Jan, Iqbal, Javed, Perera, Glen, Thurner, Clemens C., Friedl, Heike, Bernkop-Schnürch, Andreas

“…The aim of the present study was the development and evaluation in vitro as well as in vivo of an oral delivery system based on a novel type of thiolated…”
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In vitro evaluation of a self-emulsifying drug delivery system (SEDDS) for nasal administration of dimenhydrinate by Leichner, Christina, Baus, Randi Angela, Jelkmann, Max, Plautz, Melanie, Barthelmes, Jan, Dünnhaupt, Sarah, Bernkop-Schnürch, Andreas

“…The objective of the study was the development and in vitro characterization of a self-emulsifying drug delivery system (SEDDS) for the nasal application of…”
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Efficient MRI labeling of endothelial progenitor cells: Design of thiolated surface stabilized superparamagnetic iron oxide nanoparticles by Shahnaz, Gul, Kremser, Christian, Reinisch, Andreas, Vetter, Anja, Laffleur, Flavia, Rahmat, Deni, Iqbal, Javed, Dünnhaupt, Sarah, Salvenmoser, Willi, Tessadri, Richard, Griesser, Ulrich, Bernkop-Schnürch, Andreas

“…Schematic presentation for the internalization [A] of thiolated surface stabilized superparamagnetic iron oxide nanoparticles [TSS-SPIONs] and MRI signal…”
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Thiomer nanoparticles: stabilization via covalent cross-linking by Barthelmes, Jan, Dünnhaupt, Sarah, Hombach, Juliane, Bernkop-Schnürch, Andreas

“…The purpose of this study was the development of stable thiomer nanoparticles for mucosal drug delivery. Chitosan-thioglycolic acid (chitosan-TGA)…”
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