Search Results - "Du Pasquier, Louis"
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The genetic basis of resistance and matching-allele interactions of a host-parasite system: The Daphnia magna-Pasteuria ramosa model
Published in PLoS genetics (21-02-2017)“…Negative frequency-dependent selection (NFDS) is an evolutionary mechanism suggested to govern host-parasite coevolution and the maintenance of genetic…”
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2
Lymphoid Tissue in Teleost Gills: Variations on a Theme
Published in Biology (Basel, Switzerland) (01-06-2020)“…In bony fish, the gill filaments are essential for gas exchanges, but also are vulnerable to infection by water-borne microorganisms. Omnipresent across fish,…”
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3
No more non-model species: The promise of next generation sequencing for comparative immunology
Published in Developmental and comparative immunology (01-07-2014)“…•Comparative immunologists are facing many challenges that can be solved using NGS.•NGS will circumvent the need for genome sequences in non-model species.•NGS…”
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A large repertoire of parasite epitopes matched by a large repertoire of host immune receptors in an invertebrate host/parasite model
Published in PLoS neglected tropical diseases (07-09-2010)“…For many decades, invertebrate immunity was believed to be non-adaptive, poorly specific, relying exclusively on sometimes multiple but germ-line encoded…”
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5
Origin of Immunoglobulin Isotype Switching
Published in Current biology (22-05-2012)“…From humans to frogs, immunoglobulin class switching introduces different effector functions to antibodies through an intrachromosomal DNA recombination…”
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6
Immunological memory: What's in a name?
Published in Immunological reviews (01-05-2018)“…Summary Immunological memory is one of the core topics of contemporary immunology. Yet there are many discussions about what this concept precisely means,…”
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The B7 family of immunoregulatory receptors: A comparative and evolutionary perspective
Published in Molecular immunology (2009)“…In mammals, T cell activation requires specific recognition of the peptide–MHC complex by the TcR and co-stimulatory signals. Important co-stimulatory…”
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Dscam1 in Pancrustacean Immunity: Current Status and a Look to the Future
Published in Frontiers in immunology (09-06-2017)“…The ( ) gene is an extraordinary example of diversity: by combining alternatively spliced exons, thousands of isoforms can be produced from just one gene. So…”
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On the origins of the adaptive immune system: novel insights from invertebrates and cold-blooded vertebrates
Published in Trends in immunology (01-02-2004)“…When and how adaptive immunity emerged is one of the fundamental questions in immunology. Accumulated evidence suggests that the key components of adaptive…”
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10
chicken leukocyte receptor complex encodes a primordial, activating, high-affinity IgY Fc receptor
Published in Proceedings of the National Academy of Sciences - PNAS (10-07-2007)“…Fc receptors are key players of the immune system that link the fine specificity of immunoglobulins and innate effector responses. Here, we describe a…”
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Evidence for a Functional Second Thymus in Mice
Published in Science (American Association for the Advancement of Science) (14-04-2006)“…The thymus organ supports the development of T cells and is located in the thorax. Here, we report the existence of a second thymus in the mouse neck, which…”
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12
CD96 Interaction with CD155 via Its First Ig-like Domain Is Modulated by Alternative Splicing or Mutations in Distal Ig-like Domains
Published in The Journal of biological chemistry (23-01-2009)“…The adhesion receptor CD96 (TACTILE) is a transmembrane glycoprotein possessing three extracellular immunoglobulin-like domains. Among peripheral blood cells,…”
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Heterogeneity of endothelial junctions is reflected by differential expression and specific subcellular localization of the three JAM family members
Published in Blood (15-12-2001)“…Endothelial cells are linked to each other through intercellular junctional complexes that regulate the barrier and fence function of the vascular wall. The…”
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Genomic analysis of immunity in a Urochordate and the emergence of the vertebrate immune system: "waiting for Godot"
Published in Immunogenetics (New York) (01-11-2003)“…Genome-wide sequence analysis in the invertebrate chordate, Ciona intestinalis, has provided a comprehensive picture of immune-related genes in an organism…”
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The fate of duplicated immunity genes in the dodecaploid Xenopus ruwenzoriensis
Published in Frontiers in bioscience (01-01-2009)“…The relatively recent dodecaploid Xenopus (X.) ruwenzoriensis (108 chromosomes) permits to catch the phenomenon of gene silencing or modification in the act…”
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Cytokine Receptor Diversity in the Lamprey Predicts the Minimal Essential Cytokine Networks of Vertebrates
Published in The Journal of immunology (1950) (01-09-2022)“…The vertebrate adaptive immune systems (Agnatha and Gnathostomata) use sets of T and B lymphocyte lineages that somatically generate highly diverse repertoires…”
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The Chicken Leukocyte Receptor Complex: A Highly Diverse Multigene Family Encoding at Least Six Structurally Distinct Receptor Types
Published in The Journal of immunology (1950) (01-07-2005)“…The chicken Ig-like receptors (CHIR) have been described as two Ig domain molecules with long cytoplasmic tails containing inhibitory motifs. In this study, we…”
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18
Long-term balancing selection for pathogen resistance maintains trans-species polymorphisms in a planktonic crustacean
Published in Nature communications (22-06-2024)“…Balancing selection is an evolutionary process that maintains genetic polymorphisms at selected loci and strongly reduces the likelihood of allele fixation…”
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Genome-Wide Association Analysis Identifies a Genetic Basis of Infectivity in a Model Bacterial Pathogen
Published in Molecular biology and evolution (16-12-2020)“…Abstract Knowledge of the genetic architecture of pathogen infectivity and host resistance is essential for a mechanistic understanding of coevolutionary…”
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Immunoreceptor tyrosine-based inhibition motifs: a quest in the past and future
Published in Immunological reviews (01-08-2008)“…Since an immunoreceptor tyrosine-based inhibition motif (ITIM) was first identified in the intracytoplasmic domain of FcγRIIB, ITIMs have been found in a large…”
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