Search Results - "Du, Ziyun"

KLF4 expression enhances the efficacy of chemotherapy drugs in ovarian cancer cells by Wang, Baojin, Shen, Airong, Ouyang, Xuan, Zhao, Guannan, Du, Ziyun, Huo, Wenying, Zhang, Tao, Wang, Yinan, Yang, Chuanhe, Dong, Peixin, Watari, Hidemichi, Pfeffer, Lawrence M., Yue, Junming

“…KLF4 is a transcriptional factor that can function either as a tumor suppressor or oncogene in cancer based on its cellular context. We recently demonstrated…”
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Molecular heterogeneity in a patient-derived glioblastoma xenoline is regulated by different cancer stem cell populations by Garner, Jo Meagan, Ellison, David W, Finkelstein, David, Ganguly, Debolina, Du, Ziyun, Sims, Michelle, Yang, Chuan He, Interiano, Rodrigo B, Davidoff, Andrew M, Pfeffer, Lawrence M

“…Malignant glioblastoma (GBM) is a highly aggressive brain tumor with a dismal prognosis and limited therapeutic options. Genomic profiling of GBM samples has…”
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Curcumin potentiates rhabdomyosarcoma radiosensitivity by suppressing NF-κB activity by Orr, W Shannon, Denbo, Jason W, Saab, Karim R, Ng, Catherine Y, Wu, Jianrong, Li, Kui, Garner, Jo Meagan, Morton, Christopher L, Du, Ziyun, Pfeffer, Lawrence M, Davidoff, Andrew M

“…Ionizing radiation (IR) is an essential component of therapy for alveolar rhabdomyosarcoma. Nuclear factor-kappaB (NF-κΒ) transcription factors are upregulated…”
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Inhibition of type I interferon-mediated antiviral action in human glioma cells by the IKK inhibitors BMS-345541 and TPCA-1 by Du, Ziyun, Whitt, Michael A, Baumann, Jessica, Garner, Jo Meagan, Morton, Christopher L, Davidoff, Andrew M, Pfeffer, Lawrence M

“…The nuclear factor-kappa B (NFκB) signal transduction pathway plays an important role in immunity, inflammation, cell growth, and survival. Since dysregulation…”
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Correction: Molecular Heterogeneity in a Patient-Derived Glioblastoma Xenoline is Regulated by Different Cancer Stem Cell Populations by Garner, Jo Meagan, Ellison, David W, Finkelstein, David, Ganguly, Debolina, Du, Ziyun, Sims, Michelle, Yang, Chuan He, Interiano, Rodrigo B, Davidoff, Andrew M, Pfeffer, Lawrence M

“…[This corrects the article DOI: 10.1371/journal.pone.0125838.]…”
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Interferon-resistant Daudi Cell Line with a Stat2 Defect Is Resistant to Apoptosis Induced by Chemotherapeutic Agents by Du, Ziyun, Fan, Meiyun, Kim, Jong-Gwan, Eckerle, Dara, Lothstein, Leonard, Wei, Lai, Pfeffer, Lawrence M.

“…Interferon-α (IFNα) has shown promise in the treatment of various cancers. However, the development of IFN resistance is a significant drawback. Using…”
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Identification of CXCL11 as a STAT3-Dependent Gene Induced by IFN by Yang, Chuan He, Wei, Lai, Pfeffer, Susan R, Du, Ziyun, Murti, Aruna, Valentine, William J, Zheng, Yi, Pfeffer, Lawrence M

“…IFNs selectively regulate gene expression through several signaling pathways. The present study explored the involvement of STAT3 in the IFN-induced expression…”
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Observation of Calcium-dependent Unidirectional Rotational Motion in Recombinant Photosynthetic F1-ATPase Molecules by Tucker, Ward C, Schwarz, Alon, Levine, Tiferet, Du, Ziyun, Gromet-Elhanan, Zippora, Richter, Mark L, Haran, Gilad

“…ATP hydrolysis and synthesis by the F 0 F 1 -ATP synthase are coupled to proton translocation across the membrane in the presence of magnesium. Calcium is…”
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Constitutive Activation of Signal Transducer and Activator of Transcription 3 (STAT3) and Nuclear Factor κB Signaling in Glioblastoma Cancer Stem Cells Regulates the Notch Pathway by Garner, Jo Meagan, Fan, Meiyun, Yang, Chuan He, Du, Ziyun, Sims, Michelle, Davidoff, Andrew M., Pfeffer, Lawrence M.

“…Malignant gliomas are locally aggressive, highly vascular tumors that have a dismal prognosis, and present therapies provide little improvement in the disease…”
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Orally Bioavailable Androgen Receptor Degrader, Potential Next-Generation Therapeutic for Enzalutamide-Resistant Prostate Cancer by Ponnusamy, Suriyan, He, Yali, Hwang, Dong-Jin, Thiyagarajan, Thirumagal, Houtman, Rene, Bocharova, Vera, Sumpter, Bobby G, Fernandez, Elias, Johnson, Daniel, Du, Ziyun, Pfeffer, Lawrence M, Getzenberg, Robert H, McEwan, Iain J, Miller, Duane D, Narayanan, Ramesh

“…Androgen receptor (AR)-targeting prostate cancer drugs, which are predominantly competitive ligand-binding domain (LBD)-binding antagonists, are inactivated by…”
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Unphosphorylated STAT3 regulates the antiproliferative, antiviral, and gene-inducing actions of type I interferons by Pfeffer, Susan R., Fan, Meiyun, Du, Ziyun, Yang, Chuan He, Pfeffer, Lawrence M.

“…Type I interferon (IFNα/β) induces antiviral and antiproliferative responses in cells through the induction of IFN-stimulated genes (ISGs). Although the roles…”
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The effects of type I interferon on glioblastoma cancer stem cells by Du, Ziyun, Cai, Chun, Sims, Michelle, Boop, Frederick A., Davidoff, Andrew M., Pfeffer, Lawrence M.

“…Glioblastomas (GBMs) are highly invasive brain tumors that are extremely deadly. The highly aggressive nature of GBM as well as its heterogeneity at the…”
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Pro-inflammatory Genes as Biomarkers and Therapeutic Targets in Oral Squamous Cell Carcinoma by Rao, Shailaja K., Pavicevic, Zoran, Du, Ziyun, Kim, Jong-Gwan, Fan, Meiyun, Jiao, Yan, Rosebush, Molly, Samant, Sandeep, Gu, Weikuan, Pfeffer, Lawrence M., Nosrat, Christopher A.

“…Oral squamous cell carcinoma (OSCC) is a major health problem worldwide, and patients have a particularly poor 5-year survival rate. Thus, identification of…”
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The Role of TRAF2 Binding to the Type I Interferon Receptor in Alternative NFκB Activation and Antiviral Response by Yang, Chuan He, Murti, Aruna, Pfeffer, Susan R., Fan, Meiyun, Du, Ziyun, Pfeffer, Lawrence M.

“…Type I interferons (IFNs) play critical roles in the host defense by modulating gene expression through the IFN-dependent activation of STAT and NFκB…”
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Molecular biological approaches to unravel adenylyl cyclase signaling and function by Patel, T B, Du, Z, Pierre, S, Cartin, L, Scholich, K

“…Signal transduction through the cell membrane requires the participation of one or more plasma membrane proteins. For many transmembrane signaling events…”
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Curcumin Potentiates Rhabdomyosarcoma Radiosensitivity by Suppressing NF-[kappa]B Activity by Orr, W. Shannon, Denbo, Jason W, Saab, Karim R, Ng, Catherine Y, Wu, Jianrong, Li, Kui, Garner, Jo Meagan, Morton, Christopher L, Du, Ziyun, Pfeffer, Lawrence M, Davidoff, Andrew M

“…Ionizing radiation (IR) is an essential component of therapy for alveolar rhabdomyosarcoma. Nuclear factor-kappaB (NF-[kappa][BETA]) transcription factors are…”
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The role of TRAF2 binding to the type I interferon receptor in alternative NFκB activation and antiviral response. VOLUME 283 (2008) PAGES 14309-14316 by Yang, Chuan He, Murti, Aruna, Pfeffer, Susan R., Fan, Meiyun, Du, Ziyun, Pfeffer, Lawrence M.

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Copper and Zinc Inhibit Gαs Function by Gao, Xianlong, Du, Ziyun, Patel, Tarun B.

“…The stimulatory GTP-binding protein of adenylyl cyclase (AC) regulates hormone-stimulated production of cAMP. Here, we demonstrate that Cu2+ and Zn2+ inhibit…”
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Copper and Zinc Inhibit Gαs Function by Xianlong Gao, Ziyun Du, Tarun B. Patel

“…The stimulatory GTP-binding protein of adenylyl cyclase (AC) regulates hormone-stimulated production of cAMP. Here, we demonstrate that Cu 2+ and Zn 2+ inhibit…”
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Copper and zinc inhibit Galphas function: a nucleotide-free state of Galphas induced by Cu2+ and Zn2 by Gao, Xianlong, Du, Ziyun, Patel, Tarun B

“…The stimulatory GTP-binding protein of adenylyl cyclase (AC) regulates hormone-stimulated production of cAMP. Here, we demonstrate that Cu(2+) and Zn(2+)…”
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