Search Results - "Du, Yunlan"

Patients with Parkinson's disease predict a lower incidence of colorectal cancer by Fang, Hongsheng, Du, Yunlan, Pan, Shuting, Zhong, Ming, Tang, Jiayin

“…Recent theory on the "gut-brain axis" suggests a close relationship between the dysfunction of the gut and the disorders of the brain. We performed a systemic…”
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An insight into the mechanistic role of p53-mediated autophagy induction in response to proteasomal inhibition-induced neurotoxicity by Du, Yunlan, Yang, Dehua, Li, Liang, Luo, Guangrui, Li, Ting, Fan, Xiaolan, Wang, Qiang, Zhang, Xin, Wang, Yi, Le, Weidong

“…The ubiquitin-proteasome system (UPS) and the autophagy-lysosomal pathway (ALP) are the two most important components of cellular mechanisms for protein…”
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D2/D3 receptor agonist ropinirole protects dopaminergic cell line against rotenone-induced apoptosis through inhibition of caspase- and JNK-dependent pathways by Chen, Sheng, Zhang, Xiaojie, Yang, Dehua, Du, Yunlan, Li, Liang, Li, Xuping, Ming, Ming, Le, Weidong

“…Ropinirole, a D2/D3 receptor agonist has been reported to have neuroprotective effects. We showed that ropinirole can prevent rotenone-induced apoptosis in…”
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c-Jun N-Terminal Kinase Mediates Lactacystin-Induced Dopamine Neuron Degeneration by Li, Xuping, Du, Yunlan, Fan, Xiaolan, Yang, Dehua, Luo, Guangrui, Le, Weidong

“…Parkinson disease is characterized by the progressive loss of dopaminergic neurons in the substantia nigra pars compacta. It has been proposed that dysfunction…”
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HDAC6-mediated Hsp90 deacetylation reduces aggregation and toxicity of the protein alpha-synuclein by regulating chaperone-mediated autophagy by Du, Yunlan, Yang, Xiao, Li, Zezhi, Le, Weidong, Hao, Yong, Song, Yeping, Wang, Fei, Guan, Yangtai

“…Histone deacetylase 6 (HDAC6) has been shown to control major cell response pathways to the cytotoxic ubiquitinated aggregates in some protein aggregation…”
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Increased activation ability of monocytes from ALS patients by Du, Yunlan, Zhao, Weihua, Thonhoff, Jason R., Wang, Jinghong, Wen, Shixiang, Appel, Stanley H.

“…Neuroinflammation is increasingly recognized as an important mediator of disease progression in patients with amyotrophic lateral sclerosis (ALS). Recent…”
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POMP++: Facilitating Postmortem Program Diagnosis with Value-Set Analysis by Mu, Dongliang, Du, Yunlan, Xu, Jianhao, Xu, Jun, Xing, Xinyu, Mao, Bing, Liu, Peng

“…With the emergence of hardware-assisted processor tracing, execution traces can be logged with lower runtime overhead and integrated into the core dump . In…”
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Histone deacetylase 6 regulates cytotoxic α-synuclein accumulation through induction of the heat shock response by Du, Yunlan, Wang, Fei, Zou, Jing, Le, Weidong, Dong, Qing, Wang, Zhiying, Shen, Fei, Yu, Ling, Li, Yansheng

“…Abstract Abnormal aggregation of α-synuclein (α-syn) is central to the pathogenesis of Parkinson's disease (PD). Histone deacetylase 6 (HDAC6) was previously…”
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Long-term treatment with lithium alleviates memory deficits and reduces amyloid-β production in an aged Alzheimer's disease transgenic mouse model by Zhang, Xin, Heng, Xin, Li, Ting, Li, Lixi, Yang, Dehua, Zhang, Xiaojie, Du, Yunlan, Doody, Rachelle S, Le, Weidong

“…The glycogen synthase kinase-3β (GSK3β) pathway plays a central role in Alzheimer's disease (AD) and its deregulation accounts for many of the pathological…”
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Adeno-associated virus type 2 vector-mediated glial cell line-derived neurotrophic factor gene transfer induces neuroprotection and neuroregeneration in a ubiquitin-proteasome system impairment animal model of Parkinson's disease by Du, Yunlan, Zhang, Xiaojie, Tao, Qingqing, Chen, Sheng, Le, Weidong

“…The impairment of the ubiquitin-proteasome system (UPS) is a cellular mechanism underlying the neurodegenerative process in Parkinson's disease (PD). A mouse…”
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Multiple molecular pathways are involved in the neuroprotection of GDNF against proteasome inhibitor induced dopamine neuron degeneration in vivo by Du, Yunlan, Li, Xuping, Yang, Dehua, Zhang, Xiaojie, Chen, Shen, Huang, Kaixing, Le, Weidong

“…The impairment of ubiquitin-proteasome system (UPS) is a cellular mechanism underlying the neurodegenerative process in Parkinson's disease (PD). Glial cell…”
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Prenatal hypoxia may aggravate the cognitive impairment and Alzheimer’s disease neuropathology in APPSwe /PS1A246E transgenic mice by Zhang, Xin, Li, Lixi, Zhang, Xiaojie, Xie, Wenjie, Li, Liang, Yang, Dehua, Heng, Xin, Du, Yunlan, Doody, Rachelle S, Le, Weidong

“…Abstract Most cases of Alzheimer's disease (AD) arise through interactions between genetic and environmental factors. It is believed that hypoxia is an…”
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An Empirical Study on Benchmarks of Artificial Software Vulnerabilities by Geng, Sijia, Li, Yuekang, Du, Yunlan, Xu, Jun, Liu, Yang, Mao, Bing

“…Recently, various techniques (e.g., fuzzing) have been developed for vulnerability detection. To evaluate those techniques, the community has been developing…”
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Spatiotemporal Variation Characteristics of Groundwater Quality in A Semi-Arid Steppe Area in Northwest China by Li, Quansheng, Zhang, Kai, Yang, Yingming, Chong, Shan, Du, Wenfeng, He, Yunlan

“…In this paper, the open-pit coal mine in semi-arid grassland was taken as the research object. The water samples of the open-pit coal mine and its surrounding…”
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