Search Results - "Du, Yongkun"
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A label-free electrochemical immunosensor based on AuNPs/Zn/Ni-ZIF-8-800@graphene for the detection of wheat gliadin
Published in Journal of applied electrochemistry (01-03-2024)“…Wheat gliadin is thought to be the main cause of wheat allergy leading to celiac disease. In this study, we reported an electrochemical immunosensor based on…”
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TAT Nanobody Exerts Antiviral Effect against PRRSV In Vitro by Targeting Viral Nucleocapsid Protein
Published in International journal of molecular sciences (18-01-2023)“…Porcine reproductive and respiratory syndrome (PRRS) is caused by the PRRS virus (PRRSV), which has brought huge economic losses to the pork industry worldwide…”
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Identification and Pharmacological Characterization of Two Serotonin Type 7 Receptor Isoforms from Mythimna separata
Published in International journal of molecular sciences (30-12-2022)“…Serotonin (5-hydroxytryptamine, 5-HT) is an important neuroactive molecule, as neurotransmitters regulate various biological functions in vertebrates and…”
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Development of a Colloidal Gold-Based Immunochromatographic Strip for Rapid Detection of Severe Acute Respiratory Syndrome Coronavirus 2 Spike Protein
Published in Frontiers in immunology (11-03-2021)“…The outbreak and worldwide pandemic of the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have a significant impact on global economy and…”
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The Cytoprotective Enzyme Heme Oxygenase-1 Suppresses Pseudorabies Virus Replication in vitro
Published in Frontiers in microbiology (13-03-2020)“…Pseudorabies virus (PRV) infection brings about great economic losses to the swine industry worldwide, as there are currently no effective therapeutic agents…”
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African Swine Fever Virus K205R Induces ER Stress and Consequently Activates Autophagy and the NF-κB Signaling Pathway
Published in Viruses (15-02-2022)“…African swine fever virus (ASFV) is responsible for enormous economic losses in the global swine industry. The ASFV genome encodes approximate 160 proteins,…”
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A thorough investigation into the correlation between migraines and the gut microbiome: an in-depth analysis using Mendelian randomization studies
Published in Frontiers in neurology (02-07-2024)“…A growing body of evidence underscores a significant association between neurological disorders, particularly migraines, and the gut microbiota. However, a…”
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Porcine reproductive and respiratory syndrome virus non-structural protein 4 cleaves guanylate-binding protein 1 via its cysteine proteinase activity to antagonize GBP1 antiviral effect
Published in Veterinary research (Paris) (08-07-2022)“…Abstract Porcine reproductive and respiratory syndrome (PRRS) is a highly infectious disease caused by PRRS virus (PRRSV) that causes great economic losses to…”
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Development of an Effective Double Antigen Sandwich ELISA Based on p30 Protein to Detect Antibodies against African Swine Fever Virus
Published in Viruses (30-09-2022)“…African swine fever (ASF), the highly lethal swine infectious disease caused by the African swine fever virus (ASFV), is a great threat to the swine industry…”
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Development of a Directly Visualized Recombinase Polymerase Amplification-SYBR Green I Method for the Rapid Detection of African Swine Fever Virus
Published in Frontiers in microbiology (22-12-2020)“…African swine fever (ASF) is a lethal disease in swine caused by etiologic African swine fever virus (ASFV). The global spread of ASFV has resulted in huge…”
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Pseudorabies virus tegument protein US2 antagonizes antiviral innate immunity by targeting cGAS-STING signaling pathway
Published in Frontiers in immunology (02-07-2024)“…The cGAS-STING axis-mediated type I interferon pathway is a crucial strategy for host defense against DNA virus infection. Numerous evasion strategies…”
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African Swine Fever Virus MGF110-7L Induces Host Cell Translation Suppression and Stress Granule Formation by Activating the PERK/PKR-eIF2α Pathway
Published in Microbiology spectrum (21-12-2022)“…African swine fever (ASF) is a highly contagious and often lethal disease of pigs caused by ASF virus (ASFV) and recognized as the biggest killer in global…”
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Inhibition Effect of STING Agonist SR717 on PRRSV Replication
Published in Viruses (29-08-2024)“…The porcine reproductive and respiratory syndrome virus (PRRSV) belongs to the Arteriviridae family and is a single-stranded, positively stranded RNA virus…”
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Development and characterization of monoclonal antibodies against the extracellular domain of African swine fever virus structural protein, CD2v
Published in Frontiers in microbiology (18-11-2022)“…African swine fever virus (ASFV), a DNA double-stranded virus with high infectivity and mortality, causing a devastating blow to the pig industry and the world…”
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A Novel Linear B-Cell Epitope on the P54 Protein of African Swine Fever Virus Identified Using Monoclonal Antibodies
Published in Viruses (28-03-2023)“…The African swine fever virus (ASFV) is a highly infectious viral pathogen that presents a major threat to the global pig industry. No effective vaccine is…”
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Isolation and Genetic Characterization of Parvoviruses From Dogs, Cats, Minks, and Raccoon Dogs in the Eastern Region of Shandong Province, China
Published in Frontiers in microbiology (28-02-2022)“…The eastern region of Shandong province, China, is an intensive economic mink and raccoon dog breeding area. To investigate the molecular variations of…”
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Genomic analysis of almost 8,000 Salmonella genomes reveals drivers and landscape of antimicrobial resistance in China
Published in Microbiology spectrum (12-12-2023)“…We established the largest Salmonella genome database from China and presented the landscape and spatiotemporal dynamics of antimicrobial resistance genes. We…”
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Synthetic Toll-like receptor 7 ligand inhibits porcine reproductive and respiratory syndrome virus infection in primary porcine alveolar macrophages
Published in Antiviral research (01-07-2016)“…Porcine reproductive and respiratory syndrome virus (PRRSV), a common viral pathogen, causes huge annual economic losses to the swine industry worldwide. After…”
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Identification of a Linear B Cell Epitope on p54 of African Swine Fever Virus Using Nanobodies as a Novel Tool
Published in Microbiology spectrum (15-06-2023)“…African swine fever (ASF) has received great attention from the swine industry due to the pandemic and the lack of vaccines or effective treatments. In the…”
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Identification of three conserved linear B cell epitopes on the SARS-CoV-2 spike protein
Published in Emerging microbes & infections (31-12-2022)“…Spike (S) glycoprotein is the most significant structural protein of SARS-CoV-2 and a key target for neutralizing antibodies. In light of the on-going…”
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