Search Results - "Du, William"

Foxo3 circular RNA retards cell cycle progression via forming ternary complexes with p21 and CDK2 by Du, William W, Yang, Weining, Liu, Elizabeth, Yang, Zhenguo, Dhaliwal, Preet, Yang, Burton B

“…Most RNAs generated by the human genome have no protein-coding ability and are termed non-coding RNAs. Among these include circular RNAs, which include exonic…”
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Induction of tumor apoptosis through a circular RNA enhancing Foxo3 activity by Du, William W, Fang, Ling, Yang, Weining, Wu, Nan, Awan, Faryal Mehwish, Yang, Zhenguo, Yang, Burton B

“…Circular RNAs are a class of non-coding RNAs that are receiving extensive attention. Despite reports showing circular RNAs acting as microRNA sponges, the…”
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Foxo3 circular RNA promotes cardiac senescence by modulating multiple factors associated with stress and senescence responses by Du, William W, Yang, Weining, Chen, Yu, Wu, Zhong-Kai, Foster, Francis Stuart, Yang, Zhenguo, Li, Xiangmin, Yang, Burton B

“…Circular RNAs are a subclass of non-coding RNAs detected within mammalian cells. This study was designed to test the roles of a circular RNA circ-Foxo3 in…”
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The circular RNA circ-Ccnb1 dissociates Ccnb1/Cdk1 complex suppressing cell invasion and tumorigenesis by Fang, Ling, Du, William W., Awan, Faryal Mehwish, Dong, Jun, Yang, Burton B.

“…Circular RNAs represent a large class of non-coding RNAs that are extensively expressed in mammals. However, the functions of circular RNAs are largely…”
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Identifying and Characterizing circRNA-Protein Interaction by Du, William W, Zhang, Chao, Yang, Weining, Yong, Tianqiao, Awan, Faryal Mehwish, Yang, Burton B

“…Circular RNAs have been identified as naturally occurring RNAs that are highly represented in the eukaryotic transcriptome. Although a large number of circRNAs…”
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A circular RNA promotes tumorigenesis by inducing c-myc nuclear translocation by Yang, Qi, Du, William W, Wu, Nan, Yang, Weining, Awan, Faryal Mehwish, Fang, Ling, Ma, Jian, Li, Xiangmin, Zeng, Yan, Yang, Zhenguo, Dong, Jun, Khorshidi, Azam, Yang, Burton B

“…Circular RNAs (circRNAs) are a subclass of noncoding RNAs widely expressed in mammalian cells. We report here the tumorigenic capacity of a circRNA derived…”
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Translation of yes-associated protein (YAP) was antagonized by its circular RNA via suppressing the assembly of the translation initiation machinery by Wu, Nan, Yuan, Zhidong, Du, Kevin Y., Fang, Ling, Lyu, Juanjuan, Zhang, Chao, He, Alina, Eshaghi, Esra, Zeng, Kaixuan, Ma, Jian, Du, William W., Yang, Burton B.

“…Yap is the key component of Hippo pathway which plays crucial roles in tumorigenesis. Inhibition of Yap activity could promote apoptosis, suppress…”
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The Circular RNA Interacts with STAT3, Increasing Its Nuclear Translocation and Wound Repair by Modulating Dnmt3a and miR-17 Function by Yang, Zhen-Guo, Awan, Faryal Mehwish, Du, William W., Zeng, Yan, Lyu, Juanjuan, Wu, De, Gupta, Shaan, Yang, Weining, Yang, Burton B.

“…Delayed or impaired wound healing is a major health issue worldwide, especially in patients with diabetes and atherosclerosis. Here we show that expression of…”
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Both mature miR-17-5p and passenger strand miR-17-3p target TIMP3 and induce prostate tumor growth and invasion by Yang, Xiangling, Du, William W, Li, Haoran, Liu, Fengqiong, Khorshidi, Anna, Rutnam, Zina Jeyapalan, Yang, Burton B

“…MicroRNAs (miRNA) precursor (pre-miRNA) molecules can be processed to release a miRNA/miRNA* duplex. In the canonical model of miRNA biogenesis, one strand of…”
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YAP Circular RNA, circYap, Attenuates Cardiac Fibrosis via Binding with Tropomyosin-4 and Gamma-Actin Decreasing Actin Polymerization by Wu, Nan, Xu, Jindong, Du, William W., Li, Xiangmin, Awan, Faryal Mehwish, Li, Feiya, Misir, Sema, Eshaghi, Esra, Lyu, Juanjuan, Zhou, Le, Zeng, Kaixuan, Adil, Aisha, Wang, Sheng, Yang, Burton B.

“…Cardiac fibrosis is a common pathological feature of cardiac hypertrophy. This study was designed to investigate a novel function of Yes-associated protein…”
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An antisense circular RNA circSCRIB enhances cancer progression by suppressing parental gene splicing and translation by Ma, Jian, Du, William W., Zeng, Kaixuan, Wu, Nan, Fang, Ling, Lyu, Juanjuan, Yee, Albert J., Yang, Burton B.

“…Circular RNAs (circRNAs) represent a large group of non-coding RNAs that are widely detected in mammalian cells. Although most circRNAs are generated in a…”
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A Circular RNA Binds To and Activates AKT Phosphorylation and Nuclear Localization Reducing Apoptosis and Enhancing Cardiac Repair by Zeng, Yan, Du, William W, Wu, Yingya, Yang, Zhenguo, Awan, Faryal Mehwish, Li, Xiangmin, Yang, Weining, Zhang, Chao, Yang, Qi, Yee, Albert, Chen, Yu, Yang, Fenghua, Sun, Huan, Huang, Ren, Yee, Albert J, Li, Ren-Ke, Wu, Zhongkai, Backx, Peter H, Yang, Burton B

“…As central nodes in cardiomyocyte signaling, nuclear AKT appears to play a cardio-protective role in cardiovascular disease. Here we describe a circular RNA,…”
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The Circular RNA circSKA3 Binds Integrin β1 to Induce Invadopodium Formation Enhancing Breast Cancer Invasion by Du, William W., Yang, Weining, Li, Xiangmin, Fang, Ling, Wu, Nan, Li, Feiya, Chen, Yu, He, Qihan, Liu, Elizabeth, Yang, Zhenguo, Awan, Faryal Mehwish, Liu, Mingyao, Yang, Burton B.

“…Metastatic cancer cells invade surrounding tissues by forming dynamic actin-based invadopodia, which degrade the surrounding extracellular matrix and allow…”
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Enhanced breast cancer progression by mutant p53 is inhibited by the circular RNA circ-Ccnb1 by Fang, Ling, Du, William W., Lyu, Juanjuan, Dong, Jun, Zhang, Chao, Yang, Weining, He, Alina, Kwok, Yat Sze Sheila, Ma, Jian, Wu, Nan, Li, Feiya, Awan, Faryal Mehwish, He, Chengyan, Yang, Bing L., Peng, Chun, MacKay, Helen J., Yee, Albert J., Yang, Burton B.

“…TP53 mutations occur in many different types of cancers that produce mutant p53 proteins. The mutant p53 proteins have lost wild-type p53 activity and gained…”
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Expression of versican 3'-untranslated region modulates endogenous microRNA functions by Lee, Daniel Y, Jeyapalan, Zina, Fang, Ling, Yang, Jennifer, Zhang, Yaou, Yee, Albert Y, Li, Minhui, Du, William W, Shatseva, Tatiana, Yang, Burton B

“…Mature microRNAs (miRNAs) are single-stranded RNAs that regulate post-transcriptional gene expression. In our previous study, we have shown that versican…”
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The pseudogene TUSC2P promotes TUSC2 function by binding multiple microRNAs by Rutnam, Zina Jeyapalan, Du, William W., Yang, Weining, Yang, Xiangling, Yang, Burton B.

“…Various non-coding regions of the genome, once presumed to be ‘junk’ DNA, have recently been found to be transcriptionally active. In particular, pseudogenes…”
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A Neuroligin Isoform Translated by circNlgn Contributes to Cardiac Remodeling by Du, William W., Xu, Jindong, Yang, Weining, Wu, Nan, Li, Feiya, Zhou, Le, Wang, Sheng, Li, Xiangmin, He, Alina T., Du, Kevin Y., Zeng, Kaixuan, Ma, Jian, Lyu, Juanjuan, Zhang, Chao, Zhou, Chi, Maksimovic, Katarina, Yang, Burton B.

“…[Figure: see text]…”
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Posttranscriptional regulation of AKT by circular RNA angiomotin- like 1 mediates chemoresistance against paclitaxel in breast cancer cells by Ma, Jian, Fang, Ling, Yang, Qi, Hibberd, Steven, Du, William W, Wu, Nan, Yang, Burton B

“…Chemoresistance of triple negative breast cancer against paclitaxel (PAX) is one of the major issues for the patients under chemotherapy. However, the…”
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Curcumin represses mouse 3T3-L1 cell adipogenic differentiation via inhibiting miR-17-5p and stimulating the Wnt signalling pathway effector Tcf7l2 by Tian, Lili, Song, Zhuolun, Shao, Weijuan, Du, William W, Zhao, Lisa R, Zeng, Kejing, Yang, Burton B, Jin, Tianru

“…Understanding mechanisms underlying adipogenic differentiation may lead to the discovery of novel therapeutic targets for obesity. Wnt signalling pathway…”
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Silencing mouse circular RNA circSlc8a1 by circular antisense cA-circSlc8a1 induces cardiac hepatopathy by Wu, Nan, Li, Feiya, Yang, Weining, Du, William W., Awan, Faryal Mehwish, Zhang, Chao, Lyu, Juanjuan, Misir, Sema, Zeng, Kaixuan, Eshaghi, Esra, Yang, Burton B.

“…Circular RNAs (circRNAs) are a group of non-coding RNAs with a unique circular structure generated by back-splicing. It is acknowledged that circRNAs play…”
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