Search Results - "Du, Quan"
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Mathematical modeling of interaction between innate and adaptive immune responses in COVID‐19 and implications for viral pathogenesis
Published in Journal of medical virology (01-09-2020)“…We have applied mathematical modeling to investigate the infections of the ongoing coronavirus disease‐2019 (COVID‐19) pandemic caused by SARS‐CoV‐2 virus. We…”
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Saikosaponin D: review on the antitumour effects, toxicity and pharmacokinetics
Published in Pharmaceutical biology (01-01-2021)“…Bupleuri Radix, the dried root of Bupleurum chinense DC and Bupleurum scorzonerifolium Willd (Apiaceae), is an important medicinal herb widely used to treat…”
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Simple and Safe Synthesis of Yolk-Shell-Structured Silicon/Carbon Composites with Enhanced Electrochemical Properties
Published in Molecules (Basel, Switzerland) (14-03-2024)“…With its substantial theoretical capacity, silicon (Si) is a prospective anode material for high-energy-density lithium-ion batteries (LIBs). However, the…”
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A naturally occurring antiviral ribonucleotide encoded by the human genome
Published in Nature (London) (01-06-2018)“…Viral infections continue to represent major challenges to public health, and an enhanced mechanistic understanding of the processes that contribute to viral…”
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Fast detection of hypobromous acid in cells and the water environment using a lysosome-targeted fluorescent probe
Published in Organic & biomolecular chemistry (07-02-2024)“…A new fluorescent probe SWJT-23 with lysosomal targeting ability for detection of hypobromous acid (HBrO) was synthesised based on the naphthalimide skeleton…”
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Human DNMT1 transition state structure
Published in Proceedings of the National Academy of Sciences - PNAS (15-03-2016)“…Human DNA methyltransferase 1 (DNMT1) maintains the epigenetic state of DNA by replicating CpG methylation signatures from parent to daughter strands,…”
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2-Methoxyestradiol Alleviates Neuroinflammation and Brain Edema in Early Brain Injury After Subarachnoid Hemorrhage in Rats
Published in Frontiers in cellular neuroscience (26-04-2022)“…Numerous studies have shown that neuroinflammation and brain edema play an important role in early brain injury (EBI) after subarachnoid hemorrhage (SAH)…”
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Network Pharmacology and Molecular Docking Analysis on Pharmacological Mechanisms of Astragalus membranaceus in the Treatment of Gastric Ulcer
Published in Evidence-based complementary and alternative medicine (2022)“…Background. Astragalus membranaceus (AM, family: Leguminosae) exerts significant therapeutic effect on gastric ulcer (GU); however, there are scarce studies on…”
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Sol-Gel Synthesis and Photoluminescence Properties of a Far-Red Emitting Phosphor BaLaMgTaO6:Mn4+ for Plant Growth LEDs
Published in Materials (28-05-2023)“…Far-red (FR) emitting LEDs are known as a promising supplement light source for photo-morphogenesis of plants, in which FR emitting phosphors are indispensable…”
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Effect of probiotics on the incidence of ventilator-associated pneumonia in critically ill patients: a randomized controlled multicenter trial
Published in Intensive care medicine (01-06-2016)“…Purpose To evaluate the potential preventive effect of probiotics on ventilator-associated pneumonia (VAP). Methods This was an open-label, randomized,…”
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Growth mechanism and electronic and magnetic properties of AgnTi alloy clusters
Published in The Journal of physics and chemistry of solids (01-01-2021)“…The growth behavior and electronic and magnetic properties of AgnTi (n = 1–16) clusters have been studied by using density functional theory and unbiased…”
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Construction of long non-coding RNA- and microRNA-mediated competing endogenous RNA networks in alcohol-related esophageal cancer
Published in PloS one (15-06-2022)“…The current study aimed to explore the lncRNA-miRNA-mRNA networks associated with alcohol-related esophageal cancer (EC). RNA-sequencing and clinical data were…”
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Prior statin use and intravenous thrombolysis in acute ischemic stroke: a meta-analysis of cohort studies
Published in Neurology Asia (01-12-2022)“…Background: There is uncertainty whether prior statin use (PSU) influences the outcomes of intravenous thrombolysis (IVT) in acute ischemic stroke (AIS)…”
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POU2F2 promotes the proliferation and motility of lung cancer cells by activating AGO1
Published in BMC pulmonary medicine (08-04-2021)“…To detect and investigate the expression of POU domain class 2 transcription factor 2 (POU2F2) in human lung cancer tissues, its role in lung cancer…”
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POU2F2 aggravates cell proliferation and autophagy in lung adenocarcinoma
Published in Journal of men's health (Amsterdam) (01-07-2024)“…Lung adenocarcinoma (LUAD) is one deadly tumor with high incidence. POU class 2 homeobox 2 (POU2F2) has been notarized to exhibit roles in the regulation of…”
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Longitudinal change of serum AIM2 levels after aneurysmal subarachnoid hemorrhage and its prognostic significance: a two-center prospective cohort study
Published in Scientific reports (07-05-2024)“…Absent in melanoma 2 (AIM2) is implicated in neuroinflammation. Here, we explored the prognostic significance of serum AIM2 in human aneurysmal subarachnoid…”
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Investigation of the pan-cancer property of FNDC1 and its molecular mechanism to promote lung adenocarcinoma metastasis
Published in Translational oncology (01-06-2024)“…•FNDC1 plays a crucial role in tumors progression and can be used as a therapeutic target.•FNDC1 is implicated in poor prognosis of a diverse range of…”
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Gastrodin Prevents Neuronal Apoptosis and Improves Neurological Deficits in Traumatic Brain Injury Rats through PKA/CREB/Bcl2 Axis
Published in Frontiers in bioscience (Landmark. Print) (18-05-2023)“…Gastrodin (Gas) exhibits anti-inflammatory properties against diseases associated with the central nervous system (CNS). This study aimed to investigate the…”
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Huperzine A ameliorates neurological deficits after spontaneous subarachnoid hemorrhage through endothelial cell pyroptosis inhibition
Published in Acta biochimica et biophysica Sinica (26-03-2024)“…Spontaneous subarachnoid hemorrhage (SAH) is a kind of hemorrhagic stroke which causes neurological deficits in survivors. Huperzine A has a neuroprotective…”
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