Search Results - "Du, Peishuang"

PARP12 suppresses Zika virus infection through PARP-dependent degradation of NS1 and NS3 viral proteins by Li, Lili, Zhao, Hui, Liu, Ping, Li, Chunfeng, Quanquin, Natalie, Ji, Xue, Sun, Nina, Du, Peishuang, Qin, Cheng-Feng, Lu, Ning, Cheng, Genhong

“…Zika virus infection stimulates a type I interferon (IFN) response in host cells, which suppresses viral replication. Type I IFNs exert antiviral effects by…”
Get more information

Glycyrrhetinic acid alleviates hepatic inflammation injury in viral hepatitis disease via a HMGB1-TLR4 signaling pathway by Shi, Xiaodong, Yu, Lijia, Zhang, Yinglin, Liu, Zequan, Zhang, Huawei, Zhang, Yansong, Liu, Ping, Du, Peishuang

“…•Licorice defect in TCM recipes leads to the hepatotoxicity in administrated mice.•GA inhibits viral hepatitis by suppressing HMGB1 release and cytokine…”
Get full text

25-Hydroxycholesterol Protects Host against Zika Virus Infection and Its Associated Microcephaly in a Mouse Model by Li, Chunfeng, Deng, Yong-Qiang, Wang, Shuo, Ma, Feng, Aliyari, Roghiyh, Huang, Xing-Yao, Zhang, Na-Na, Watanabe, Momoko, Dong, Hao-Long, Liu, Ping, Li, Xiao-Feng, Ye, Qing, Tian, Min, Hong, Shuai, Fan, Junwan, Zhao, Hui, Li, Lili, Vishlaghi, Neda, Buth, Jessie E., Au, Connie, Liu, Ying, Lu, Ning, Du, Peishuang, Qin, F. Xiao-Feng, Zhang, Bo, Gong, Danyang, Dai, Xinghong, Sun, Ren, Novitch, Bennett G., Xu, Zhiheng, Qin, Cheng-Feng, Cheng, Genhong

“…Zika virus (ZIKV) has become a public health threat due to its global transmission and link to severe congenital disorders. The host immune responses to ZIKV…”
Get full text

Type-I-IFN-Stimulated Gene TRIM5γ Inhibits HBV Replication by Promoting HBx Degradation by Tan, Guangyun, Yi, Zhaohong, Song, Hongxiao, Xu, Fengchao, Li, Feng, Aliyari, Roghiyh, Zhang, Hong, Du, Peishuang, Ding, Yanhua, Niu, Junqi, Wang, Xiaosong, Su, Lishan, Qin, F. Xiao-Feng, Cheng, Genhong

“…To understand the molecular mechanisms that mediate the anti-hepatitis B virus (HBV) effect of interferon (IFN) therapy, we conduct high-throughput bimolecular…”
Get full text

Interleukin-6 induces Gr-1+CD11b+ myeloid cells to suppress CD8+ T cell-mediated liver injury in mice by Cheng, Liang, Wang, Jun, Li, Xiaozhu, Xing, Qiao, Du, Peishuang, Su, Lishan, Wang, Shengdian

“…Agonist antibodies against CD137 (4-1BB) on T lymphocytes are used to increase host anti-tumor immunity, but often leading to severe liver injury in treated…”
Get full text

Type-IInterferon-Inducible SERTAD3 Inhibits Influenza A Virus Replication by Blocking the Assembly of Viral RNA Polymerase Complex by Sun, Nina, Li, Chunfeng, Li, Xiao-Feng, Deng, Yong-Qiang, Jiang, Tao, Zhang, Na-Na, Zu, Shulong, Zhang, Rong-Rong, Li, Lili, Chen, Xiang, Liu, Ping, Gold, Sarah, Lu, Ning, Du, Peishuang, Wang, Jingfeng, Qin, Cheng-Feng, Cheng, Genhong

“…Influenza A virus (IAV) infection stimulates a type I interferon (IFN-I) response in host cells that exerts antiviral effects by inducing the expression of…”
Get full text

SCARB2/LIMP-2 Regulates IFN Production of Plasmacytoid Dendritic Cells by Mediating Endosomal Translocation of TLR9 and Nuclear Translocation of IRF7 by Guo, Hao, Zhang, Jialong, Zhang, Xuyuan, Wang, Yanbing, Yu, Haisheng, Yin, Xiangyun, Li, Jingyun, Du, Peishuang, Plumas, Joel, Chaperot, Laurence, Chen, Jianzhu, Su, Lishan, Liu, Yongjun, Zhang, Liguo

“…Scavenger receptor class B, member 2 (SCARB2) is essential for endosome biogenesis and reorganization and serves as a receptor for both β-glucocerebrosidase…”
Get full text

Efficient isolation of mouse liver NKT cells by perfusion by Fang, Xianfeng, Du, Peishuang, Liu, Yang, Tang, Jie

“…NKT cell is a population of unconventional T cells that mediate both innate and adaptive T cell responses. Since NKT cells are most abundant in the liver, much…”
Get full text

Death receptor 6 is a novel plasmacytoid dendritic cell-specific receptor and modulates type I interferon production by Li, Jingyun, Du, Qiumei, Hu, Rui, Wang, Yanbing, Yin, Xiangyun, Yu, Haisheng, Du, Peishuang, Plumas, Joël, Chaperot, Laurence, Liu, Yong-jun, Zhang, Liguo

“…Dear Editor, Plasmacytoid dendritic cells （pDCs） are the professional type I interferon-producing cells of the immune system, which rapidly produce massive…”
Get full text

CD24 polymorphisms affect risk and progression of chronic hepatitis B virus infection by Li, Dongling, Zheng, Linghua, Jin, Lei, Zhou, Yuesu, Li, Haiying, Fu, Junliang, Shi, Ming, Du, Peishuang, Wang, Lizhong, Wu, Hao, Chen, Guo‐Yun, Zheng, Pan, Liu, Yang, Wang, Fu‐Sheng, Wang, Shengdian

“…T‐cell immunity to hepatitis B virus (HBV) is involved in both viral clearance and the pathogenesis of cirrhosis and hepatocellular carcinoma following chronic…”
Get full text

CD24 Is a Genetic Modifier for Risk and Progression of Multiple Sclerosis by Zhou, Qunmin, Rammohan, Kottil, Lin, Shili, Robinson, Nikki, Li, Ou, Liu, Xingluo, Bai, Xue-feng, Yin, Lijie, Scarberry, Bruce, Du, Peishuang, You, Ming, Guan, Kunliang, Zheng, Pan, Liu, Yang

“…Multiple sclerosis (MS) is a chronic neurological disease of unknown etiology, but a genetic basis for the disease is undisputed. We have reported that CD24 is…”
Get full text

Adaptive immune cells temper initial innate responses by Fu, Yang-Xin, Auh, Sogyong, Yang, Xuanming, Du, Peishuang, Dong Kim, Kwang, Zhao, Jie, Tang, Hong

“…Toll-like receptors (TLRs) recognize conserved microbial structures called pathogen-associated molecular patterns. Signaling from TLRs leads to upregulation of…”
Get full text

Interferon-Inducible Cholesterol-25-Hydroxylase Inhibits Hepatitis C Virus Replication via Distinct Mechanisms by Chen, Yongzhi, Wang, Shanshan, Yi, Zhaohong, Tian, Huabin, Aliyari, Roghiyh, Li, Yanhua, Chen, Gang, Liu, Ping, Zhong, Jin, Chen, Xinwen, Du, Peishuang, Su, Lishan, Qin, F. Xiao-Feng, Deng, Hongyu, Cheng, Genhong

“…Cholesterol 25-hydroxylase (CH25H) as an interferon-stimulated gene (ISG) has recently been shown to exert broad antiviral activity through the production of…”
Get full text

Hyper-IL-15 suppresses metastatic and autochthonous liver cancer by promoting tumour-specific CD8+ T cell responses by Cheng, Liang, Du, Xuexiang, Wang, Zheng, Ju, Jianqi, Jia, Mingming, Huang, Qibin, Xing, Qiao, Xu, Meng, Tan, Yi, Liu, Mingyue, Du, Peishuang, Su, Lishan, Wang, Shengdian

“…Background & Aims Liver cancer has a very dismal prognosis due to lack of effective therapy. Here, we studied the therapeutic effects of hyper-interleukin15…”
Get full text

TNF receptor 1 mediates dendritic cell maturation and CD8 T cell response through two distinct mechanisms by Ding, Xilai, Yang, Wei, Shi, Xiaodong, Du, Peishuang, Su, Lishan, Qin, Zhihai, Chen, Jianzhu, Deng, Hongyu

“…TNF-α and its two receptors (TNFR1 and 2) are known to stimulate dendritic cell (DC) maturation and T cell response. However, the specific receptor and…”
Get full text

Characterization of species-specific genes regulated by E2-2 in human plasmacytoid dendritic cells by Cheng, Menglan, Zhang, Xuyuan, Yu, Haisheng, Du, Peishuang, Plumas, Joël, Chaperot, Laurance, Su, Lishan, Zhang, Liguo

“…Dendritic cells (DCs) are sentinels of the immune system and comprise two distinct subsets: conventional DCs (cDCs) and plasmacytoid DCs (pDCs). Human pDCs are…”
Get full text

CD24–p53 axis suppresses diethylnitrosamine-induced hepatocellular carcinogenesis by sustaining intrahepatic macrophages by Li, Dongling, Hu, Minling, Liu, Ying, Ye, Peiying, Du, Peishuang, Li, Chi-Shan, Cheng, Liang, Liu, Ping, Jiang, Jing, Su, Lishan, Wang, Shengdian, Zheng, Pan, Liu, Yang

“…It is generally assumed that inflammation following diethylnitrosamine (DEN) treatment promotes development of hepatocellular carcinoma (HCC) through the…”
Get full text

Tumor Necrosis Factor Receptor 1 Mediates Dendritic Cell Maturation and CD8 T Cell Response through Two Distinct Mechanisms by Ding, Xilai, Yang, Wei, Shi, Xiaodong, Du, Peishuang, Su, Lishan, Qin, Zhihai, Chen, Jianzhu, Deng, Hongyu

“…Tumor necrosis factor alpha (TNFα) and its two receptors (TNFR1 and 2) are known to stimulate dendritic cell (DC) maturation and T cell response. However, the…”
Get full text

A new role for CD28 in the survival of autoreactive T cells in the periphery after chronic exposure to autoantigen by Gao, Jian-Xin, Chang, Xing, Zheng, Xincheng, Wen, Jing, Yin, Lijie, Du, Peishuang, Zheng, Pan, Liu, Yang

“…Recent work demonstrates that costimulatory molecules play a critical role for clonal deletion of autoreactive T cells in the thymus. The role of CD28 in the…”
Get full text

Preferential depletion of CD2 plasmacytoid dendritic cells in HIV-infected subjects by Du, Qiumei, Jiao, Yanmei, Hua, Wei, Wang, Rui, Wei, Feili, Ji, Yunxia, Du, Peishuang, Liu, Yong-Jun, Wu, Hao, Zhang, Liguo

“…Plasmacytoid dendritic cells (pDCs) are decreased in number and are functionally impaired in HIV act reasons for pDCs depletion are still unknown. It was…”
Get full text