Search Results - "Du, Hansen"

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    Spt5 accumulation at variable genes distinguishes somatic hypermutation in germinal center B cells from ex vivo-activated cells by Maul, Robert W, Cao, Zheng, Venkataraman, Lakshmi, Giorgetti, Carol A, Press, Joan L, Denizot, Yves, Du, Hansen, Sen, Ranjan, Gearhart, Patricia J

    Published in The Journal of experimental medicine (20-10-2014)
    “…Variable (V) genes of immunoglobulins undergo somatic hypermutation by activation-induced deaminase (AID) to generate amino acid substitutions that encode…”
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  3. 3

    The U1 snRNP protein U1C recognizes the 5′ splice site in the absence of base pairing by Rosbash, Michael, Du, Hansen

    Published in Nature (London) (05-09-2002)
    “…Splicing of precursor messenger RNA takes place in the spliceosome, a large RNA/protein macromolecular machine. Spliceosome assembly occurs in an ordered…”
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  4. 4

    Misregulation of the IgH Locus in Thymocytes by Kumari, Gita, Gerasimova, Tatiana, Du, Hansen, De, Supriyo, Wood, 3rd, William H, Becker, Kevin G, Sen, Ranjan

    Published in Frontiers in immunology (13-11-2018)
    “…Functional antigen receptor genes are assembled by somatic rearrangements that are largely lymphocyte lineage specific. The immunoglobulin heavy chain ( ) gene…”
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  5. 5

    A Targeted Bypass Screen Identifies Ynl187p, Prp42p, Snu71p, and Cbp80p for Stable U1 snRNP/Pre-mRNA Interaction by Hage, Rosemary, Tung, Luh, Du, Hansen, Stands, Leah, Rosbash, Michael, Chang, Tien-Hsien

    Published in Molecular and Cellular Biology (01-07-2009)
    “…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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    Activation of 12/23-RSS-Dependent RAG Cleavage by hSWI/SNF Complex in the Absence of Transcription by Du, Hansen, Ishii, Haruhiko, Pazin, Michael J., Sen, Ranjan

    Published in Molecular cell (05-09-2008)
    “…Maintenance of genomic integrity during antigen receptor gene rearrangements requires (1) regulated access of the V(D)J recombinase to specific loci and (2)…”
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  7. 7

    Using BAC transgenesis in zebrafish to identify regulatory sequences of the amyloid precursor protein gene in humans by Shakes, Leighcraft A, Du, Hansen, Wolf, Hope M, Hatcher, Charles, Norford, Derek C, Precht, Patricia, Sen, Ranjan, Chatterjee, Pradeep K

    Published in BMC genomics (04-09-2012)
    “…Non-coding DNA in and around the human Amyloid Precursor Protein (APP) gene that is central to Alzheimer's disease (AD) shares little sequence similarity with…”
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  8. 8

    Nucleophosmin/B23 Negatively Regulates GCN5-dependent Histone Acetylation and Transactivation by Zou, Yonglong, Wu, Jun, Giannone, Richard J., Boucher, Lorrie, Du, Hansen, Huang, Ying, Johnson, Dabney K., Liu, Yie, Wang, Yisong

    Published in The Journal of biological chemistry (29-02-2008)
    “…Nucleophosmin/B23 is a multifunctional phosphoprotein that is overexpressed in cancer cells and has been shown to be involved in both positive and negative…”
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    Effects of the U1C L13 mutation and temperature regulation of yeast commitment complex formation by Du, H, Tardiff, D.F, Moore, M.J, Rosbash, M

    “…The U1 small nuclear ribonucleoprotein particle U1C protein has a zinc finger-like structure (C2H2 motif) at its N terminus, which is conserved from yeast to…”
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  10. 10

    Altered 3D chromatin structure permits inversional recombination at the IgH locus by Du, Hansen, Qiu, Xiang, Zhao, Mingming, Singh, Amit, Sen, Ranjan

    Published in The Journal of immunology (1950) (01-05-2020)
    “…Abstract Immunoglobulin heavy chain (IgH) genes are assembled by two sequential DNA rearrangement events that are initiated by recombinase activating gene…”
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  11. 11

    trp RNA-binding attenuation protein-5' stem-loop RNA interaction is required for proper transcription attenuation control of the Bacillus subtilis trpEDCFBA operon by Du, H, Yakhnin, A V, Dharmaraj, S, Babitzke, P

    Published in Journal of bacteriology (01-04-2000)
    “…The trp RNA-binding attenuation protein (TRAP) regulates expression of the Bacillus subtilis trpEDCFBA operon by a novel transcription attenuation mechanism…”
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  12. 12

    Three-dimensional chromatin reorganization regulates B cell development during ageing by Ma, Fei, Cao, Yaqiang, Du, Hansen, Braikia, Fatima Zohra, Zong, Le, Ollikainen, Noah, Bayer, Marc, Qiu, Xiang, Park, Bongsoo, Roy, Roshni, Nandi, Satabdi, Sarantopoulou, Dimitra, Ziman, Andrew, Bianchi, Aisha Haley, Beerman, Isabel, Zhao, Keji, Grosschedl, Rudolf, Sen, Ranjan

    Published in Nature cell biology (01-06-2024)
    “…The contribution of three-dimensional genome organization to physiological ageing is not well known. Here we show that large-scale chromatin reorganization…”
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  13. 13

    trp RNA-binding Attenuation Protein-mediated Long Distance RNA Refolding Regulates Translation of trpE inBacillus subtilis by Du, Hansen, Babitzke, Paul

    Published in The Journal of biological chemistry (07-08-1998)
    “…Expression of the trpEDCFBA operon is regulated at both the transcriptional and translational levels by thetrp RNA-binding attenuation protein (TRAP)…”
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  14. 14

    Sequential Enhancer Sequestration Dysregulates Recombination Center Formation at the IgH Locus by Qiu, Xiang, Kumari, Gita, Gerasimova, Tatiana, Du, Hansen, Labaran, Lawal, Singh, Amit, De, Supriyo, Wood, William H., Becker, Kevin G., Zhou, Weiqiang, Ji, Hongkai, Sen, Ranjan

    Published in Molecular cell (05-04-2018)
    “…Immunoglobulin heavy-chain (IgH) genes are assembled by DNA rearrangements that juxtapose a variable (VH), a diversity (DH), and a joining (JH) gene segment…”
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  15. 15

    T cell factor 1 initiates the T helper type 2 fate by inducing the transcription factor GATA-3 and repressing interferon-γ by Moon, Hyung-Geun, Yu, Qing, Du, Hansen, Waterman, Marian L, Sharma, Archna, Salay, Theresa M, Leeds, Karen E, Wu, Beibei, Zhu, Zhou, Oh, Sun Young, Sen, Jyoti Misra, Hossain, M Zulfiquer

    Published in Nature immunology (01-09-2009)
    “…The polarization of naive CD4 + T cells to become T helper type 2 cells requires the transcription factor GATA-3. Sen and colleagues show that T cell antigen…”
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  16. 16

    Localized epigenetic changes induced by D sub(H) recombination restricts recombinase to DJ sub(H) junctions by Subrahmanyam, Ramesh, Du, Hansen, Ivanova, Irina, Chakraborty, Tirtha, Ji, Yanhong, Zhang, Yu, Alt, Frederick W, Schatz, David G, Sen, Ranjan

    Published in Nature immunology (01-12-2012)
    “…Genes encoding immunoglobulin heavy chains (Igh) are assembled by rearrangement of variable (V sub(H)), diversity (D sub(H)) and joining (J sub(H)) gene…”
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  17. 17

    Localized epigenetic changes induced by [D.sub.H] recombination restricts recombinase to [DJ.sub.H] junctions by Subrahmanyam, Ramesh, Du, Hansen, Ivanova, Irina, Chakraborty, Tirtha, Ji, Yanhong, Zhang, Yu, Alt, Frederick W, Schatz, David G, Sen, Ranjan

    Published in Nature immunology (01-12-2012)
    “…Genes encoding immunoglobulin heavy chains (Igh) are assembled by rearrangement of variable [(V.sub.H]), diversity [(D.sub.H]) and joining [(J.sub.H]) gene…”
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  18. 18

    Localized epigenetic changes induced by DH recombination restricts recombinase to DJH junctions by Subrahmanyam, Ramesh, Du, Hansen, Ivanova, Irina, Chakraborty, Tirtha, Ji, Yanhong, Zhang, Yu, Alt, Frederick W, Schatz, David G, Sen, Ranjan

    Published in Nature immunology (01-12-2012)
    “…The Igh locus undergoes a precise order of gene rearrangement during V(D)J recombination. Sen and colleagues show the recruitment of the RAG recombinase is…”
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  19. 19

    Mi2β Shows Chromatin Enzyme Specificity by Erasing a DNase I-hypersensitive Site Established by ACF by Ishii, Haruhiko, Du, Hansen, Zhang, Zhaoqing, Henderson, Angus, Sen, Ranjan, Pazin, Michael J.

    Published in The Journal of biological chemistry (20-03-2009)
    “…ATP-dependent chromatin-remodeling enzymes are linked to changes in gene expression; however, it is not clear how the multiple remodeling enzymes found in…”
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  20. 20

    Mi2β Shows Chromatin Enzyme Specificity by Erasing a DNase I-hypersensitive Site Established by ACFS by Ishii, Haruhiko, Du, Hansen, Zhang, Zhaoqing, Henderson, Angus, Sen, Ranjan, Pazin, Michael J.

    Published in The Journal of biological chemistry (20-03-2009)
    “…ATP-dependent chromatin-remodeling enzymes are linked to changes in gene expression; however, it is not clear how the multiple remodeling enzymes found in…”
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    Journal Article