Search Results - "Du, Canwei"
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Tick-Derived Peptide Blocks Potassium Channel TREK-1
Published in International journal of molecular sciences (01-08-2024)“…Ticks transmit a variety of pathogens, including rickettsia and viruses, when they feed on blood, afflicting humans and other animals. Bioactive components…”
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A Novel Peptide from Polypedates megacephalus Promotes Wound Healing in Mice
Published in Toxins (02-11-2022)“…Amphibian skin contains wound-healing peptides, antimicrobial peptides, and insulin-releasing peptides, which give their skin a strong regeneration ability to…”
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3
Molecular mechanism by which spider-driving peptide potentiates coagulation factors
Published in Biomedicine & pharmacotherapy (01-10-2023)“…Hemostasis is a crucial process that quickly forms clots at injury sites to prevent bleeding and infections. Dysfunctions in this process can lead to…”
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Two-pore channel blockade by phosphoinositide kinase inhibitors YM201636 and PI-103 determined by a histidine residue near pore-entrance
Published in Communications biology (23-07-2022)“…Human two-pore channels (TPCs) are endolysosomal cation channels and play an important role in NAADP-evoked Ca 2+ release and endomembrane dynamics. We found…”
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5
Centipede KCNQ Inhibitor SsTx Also Targets KV1.3
Published in Toxins (01-02-2019)“…It was recently discovered that Ssm Spooky Toxin (SsTx) with 53 residues serves as a key killer factor in red-headed centipede’s venom arsenal, due to its…”
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Purification and Characterization of a Novel Kazal-Type Trypsin Inhibitor from the Leech of Hirudinaria manillensis
Published in Toxins (23-07-2016)“…Kazal-type serine proteinase inhibitors are found in a large number of living organisms and play crucial roles in various biological and physiological…”
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Lsm12, an NAADP receptor, is also a PI(3,5)P2-competitive antagonist of human two pore channels
Published in Biophysical journal (11-02-2022)Get full text
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8
A Novel Peptide from IPolypedates megacephalus/I Promotes Wound Healing in Mice
Published in Toxins (01-11-2022)“…Amphibian skin contains wound-healing peptides, antimicrobial peptides, and insulin-releasing peptides, which give their skin a strong regeneration ability to…”
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9
A novel defensin-like antimicrobial peptide from the skin secretions of the tree frog, Theloderma kwangsiensis
Published in Gene (15-01-2016)“…Defensins are one of the major families of antimicrobial peptides (AMPs), and have been reported from prokaryotic to eukaryotic kingdoms. But defensins are…”
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10
A membrane disrupting toxin from wasp venom underlies the molecular mechanism of tissue damage
Published in Toxicon (Oxford) (15-06-2018)“…The molecular mechanism of the local hypersensitivity reactions to wasp venom including dermal necrosis remains an enigma regardless of the numerosity of the…”
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An immunoregulatory peptide from tsetse fly salivary glands of Glossina morsitans morsitans
Published in Biochimie (01-11-2015)“…Tsetse fly Glossina morsitans morsitans is an important insect vector of African trypanosomes, which cause human African trypanosomiasis (HAT). As other…”
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12
Centipede KCNQ Inhibitor SsTx Also Targets K V 1.3
Published in Toxins (01-02-2019)“…It was recently discovered that Ssm Spooky Toxin (SsTx) with 53 residues serves as a key killer factor in red-headed centipede's venom arsenal, due to its…”
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13
Isolation and structural identification of a potassium ion channel Kv4.1 inhibitor SsTx-P2 from centipede venom
Published in Zhejiang da xue xue bao. Journal of Zhejiang University. Medical sciences. Yi xue ban (25-04-2024)“…OBJECTIVESTo isolate a potassium ion channel Kv4.1 inhibitor from centipede venom, and to determine its sequence and structure.METHODSIon-exchange…”
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Isolation and structural identification of a potassium ion channel Kv4.1 inhibitor SsTx-P2 from centipede venom
Published in Zhejiang da xue xue bao. Journal of Zhejiang University. Medical sciences. Yi xue ban (25-01-2024)“…To isolate potassium ion channel Kv4.1 inhibitor from centipede venom, and to determine its primary and spatial structure. Ion-exchange chromatography and…”
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