Search Results - "Du, Biaoyan"

Hederagenin potentiated cisplatin- and paclitaxel-mediated cytotoxicity by impairing autophagy in lung cancer cells by Wang, Kun, Liu, Xiaodong, Liu, Quanmeng, Ho, Idy ht, Wei, Xianli, Yin, Ting, Zhan, Yujuan, Zhang, Wenjing, Zhang, Wenbo, Chen, Bonan, Gu, Jiangyong, Tan, Yuhui, Zhang, Lin, Chan, Matthew Tv, Wu, William Kk, Du, Biaoyan, Xiao, Jianyong

“…Autophagy inhibition has been demonstrated to increase the efficacy of conventional chemotherapy. In this study, we identified hederagenin, a triterpenoid…”
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Connexin 43 upregulation by dioscin inhibits melanoma progression via suppressing malignancy and inducing M1 polarization by Kou, Yu, Ji, Liyan, Wang, Haojia, Wang, Wensheng, Zheng, Hongming, Zou, Juan, Liu, Linxin, Qi, Xiaoxiao, Liu, Zhongqiu, Du, Biaoyan, Lu, Linlin

“…Connexin 43 (Cx43), a vital gap junction protein in tumor microenvironment (TME), is a novel molecular target for melanoma chemotherapeutics due to its tumor…”
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Tubeimoside I-induced lung cancer cell death and the underlying crosstalk between lysosomes and mitochondria by Wang, Kun, Zhan, Yujuan, Chen, Bonan, Lu, Yuhua, Yin, Ting, Zhou, Shikun, Zhang, Weibin, Liu, Xiaodong, Du, Biaoyan, Wei, Xianli, Xiao, Jianyong

“…Cancer cells have developed chemoresistance and have improved their survival through the upregulation of autophagic mechanisms that protect mitochondrial…”
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Structure Identification of ViceninII Extracted from Dendrobium officinale and the Reversal of TGF-β1-Induced Epithelial⁻Mesenchymal Transition in Lung Adenocarcinoma Cells through TGF-β/Smad and PI3K/Akt/mTOR Signaling Pathways by Luo, Yingyi, Ren, Zhiyao, Du, Biaoyan, Xing, Shangping, Huang, Shaowei, Li, Yunrong, Lei, Zhouxi, Li, Dan, Chen, Huanhuan, Huang, Yuechun, Wei, Gang

“…ViceninII is a naturally flavonoid glycoside extracted from , a precious Chinese traditional herb, has been proven to be valuable for cancer treatment…”
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Dioscin potentiates the antitumor effect of suicide gene therapy in melanoma by gap junction intercellular communication-mediated antigen cross-presentation by Zhang, Wenbo, Lin, Lingyun, Zhang, Yujian, Zhao, Tingxiu, Zhan, Yujuan, Wang, Huiqi, Fang, Junfeng, Du, Biaoyan

“…Dioscin (Dio), steroid saponin, exists in several medicinal herbs with potent anticancer efficacy. This study aimed to explore the effect of Dio on the…”
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Integrated analysis reveals the pivotal interactions between immune cells in the melanoma tumor microenvironment by Chen, Jiawei, Hu, Shan, Wang, Huiqi, Zhao, Tingxiu, Song, Yue, Zhong, Xueying, Luo, Qingling, Xu, Mansi, He, Lina, Chen, Qiugu, Du, Biaoyan, Xiao, Jianyong, Wang, Kun

“…Melanoma is the most lethal type of skin cancer. Despite the breakthroughs in the clinical treatment of melanoma using tumor immunotherapy, many patients do…”
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Artesunate Inhibits the Cell Growth in Colorectal Cancer by Promoting ROS-Dependent Cell Senescence and Autophagy by Huang, Zhiying, Gan, Shu, Zhuang, Xuerong, Chen, Yao, Lu, Linlin, Wang, Ying, Qi, Xiaoxiao, Feng, Qian, Huang, Qiuju, Du, Biaoyan, Zhang, Rong, Liu, Zhongqiu

“…Although artesunate has been reported to be a promising candidate for colorectal cancer (CRC) treatment, the underlying mechanisms and molecular targets of…”
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Synergistic inhibitory effect of resveratrol and TK/GCV therapy on melanoma cells by Chen, Yuan, Li, Hong, Zhang, Guangxian, Wu, Yingya, Xiao, Jianyong, Liu, Jingjing, Qiu, Pengxiang, Liu, Xijuan, Sun, Lingling, Du, Biaoyan, Tan, Yuhui

“…Purpose To investigate the synergistic effect of resveratrol on the bystander effect of TK/GCV suicide gene system in melanoma cells. Methods The effect of…”
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The Novel Autophagy Inhibitor Alpha-Hederin Promoted Paclitaxel Cytotoxicity by Increasing Reactive Oxygen Species Accumulation in Non-Small Cell Lung Cancer Cells by Zhan, Yujuan, Wang, Kun, Li, Qiao, Zou, Yidan, Chen, Bonan, Gong, Qing, Ho, Hiuting Idy, Yin, Ting, Zhang, Fangyuan, Lu, Yuhua, Wu, Weijie, Zhang, Yilin, Tan, Yuhui, Du, Biaoyan, Liu, Xiaodong, Xiao, Jianyong

“…Chemoresistance is a major limiting factor that impairs the outcome of non-small cell lung cancer (NSCLC) chemotherapy. Paclitaxel (Tax) induces protective…”
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N -Methylparoxetine Blocked Autophagic Flux and Induced Apoptosis by Activating ROS-MAPK Pathway in Non-Small Cell Lung Cancer Cells by Wang, Kun, Chen, Bonan, Yin, Ting, Zhan, Yujuan, Lu, Yuhua, Zhang, Yilin, Chen, Jiawei, Wu, Weijie, Zhou, Shikun, Mao, Wenli, Tan, Yuhui, Du, Biaoyan, Liu, Xiaodong, Ho, Hiuting Idy, Xiao, Jianyong

“…The main mechanistic function of most chemotherapeutic drugs is mediated by inducing mitochondria-dependent apoptosis. Tumor cells usually respond to…”
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AICD: an integrated anti-inflammatory compounds database for drug discovery by Wang, Kun, Xiao, Jianyong, Liu, Xiaodong, Jiang, Zhuqiao, Zhan, Yujuan, Yin, Ting, He, Lina, Zhang, Fangyuan, Xing, Shangping, Chen, Bonan, Li, Yingshi, Zhang, Fengxue, Kuang, Zaoyuan, Du, Biaoyan, Gu, Jiangyong

“…Systemic or local inflammation drives the pathogenesis of various human diseases. Small compounds with anti-inflammatory properties hold great potential for…”
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Blockage of Autophagic Flux and Induction of Mitochondria Fragmentation by Paroxetine Hydrochloride in Lung Cancer Cells Promotes Apoptosis via the ROS-MAPK Pathway by Wang, Kun, Gong, Qing, Zhan, Yujuan, Chen, Bonan, Yin, Ting, Lu, Yuhua, Zhang, Yilin, Wang, Huiqi, Ke, Junzi, Du, Biaoyan, Liu, Xiaodong, Xiao, Jianyong

“…Cancer cells are characterized by malignant proliferation and aberrant metabolism and are thereby liable to the depletion of nutrients and accumulation of…”
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Aleuritolic Acid Impaired Autophagic Flux and Induced Apoptosis in Hepatocellular Carcinoma HepG2 Cells by Yi, Hua, Wang, Kun, Du, Biaoyan, He, Lina, Ho, Hiuting, Qiu, Maosong, Zou, Yidan, Li, Qiao, Jin, Junfeng, Zhan, Yujuan, Zhao, Zhongxiang, Liu, Xiaodong

“…Aleuritolic acid (AA) is a triterpene that is isolated from the root of Geisel. In the present study, the cytotoxic effects of AA on hepatocellular carcinoma…”
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Tanshinone IIA increases the bystander effect of herpes simplex virus thymidine kinase/ganciclovir gene therapy via enhanced gap junctional intercellular communication by Xiao, Jianyong, Zhang, Guangxian, Qiu, Pengxiang, Liu, Xijuan, Wu, Yingya, Du, Biaoyan, Li, Jiefen, Zhou, Jing, Li, Jingjing, Tan, Yuhui

“…The bystander effect is an intriguing phenomenon by which adjacent cells become sensitized to drug treatment during gene therapy with herpes simplex virus…”
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Curcumin plays a synergistic role in combination with HSV-TK/GCV in inhibiting growth of murine B16 melanoma cells and melanoma xenografts by Li, Hong, Du, Haiyan, Zhang, Guangxian, Wu, Yingya, Qiu, Pengxiang, Liu, Jingjing, Guo, Jing, Liu, Xijuan, Sun, Lingling, Du, Biaoyan, Tan, Yuhui

“…Melanoma is a global concern and accounts for the major mortality of skin cancers. Herpes simplex virus thymidine kinase gene with ganciclovir (HSV-TK/GCV) is…”
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Berberine suppressed epithelial mesenchymal transition through cross-talk regulation of PI3K/AKT and RARα/RARβ in melanoma cells by Kou, Yu, Li, Lei, Li, Hong, Tan, Yuhui, Li, Bin, Wang, Kun, Du, Biaoyan

“…Berberine is a natural compound extracted from Coptidis rhizoma, and accumulating proof has shown its potent anti-tumor properties with diverse action on…”
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Resveratrol enhances the radiosensitivity of nasopharyngeal carcinoma cells by downregulating E2F1 by Tan, Yuhui, Wei, Xianli, Zhang, Wenyin, Wang, Xiaolan, Wang, Kun, Du, Biaoyan, Xiao, Jianyong

“…Identification of safe, effective radiosensitizing agents is urgently needed to improve the outcome of radiotherapy in nasopharyngeal cancer (NPC). In this…”
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Paeonol attenuates aging MRC-5 cells and inhibits epithelial–mesenchymal transition of premalignant HaCaT cells induced by aging MRC-5 cell-conditioned medium by Yang, Lihua, Xing, Shangping, Wang, Kun, Yi, Hua, Du, Biaoyan

“…Senescence-associated secretory phenotype (SASP) factors, such as IL-6 and IL-8, are extremely critical in tissue microenvironment. Senescent human fibroblasts…”
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Dioscin suppresses hepatocellular carcinoma tumor growth by inducing apoptosis and regulation of TP53, BAX, BCL2 and cleaved CASP3 by Zhang, Guangxian, Zeng, Xiancheng, Zhang, Ren, Liu, Juan, Zhang, Weici, Zhao, Yujun, Zhang, Xiaoyuan, Wu, Zhixue, Tan, Yuhui, Wu, Yingya, Du, Biaoyan

“…Hepatocellular carcinoma (HCC) is the most commonly diagnosed malignancy of the liver, occurs frequently in the setting of chronic liver injury. Although…”
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Berbamine Hydrochloride inhibits lysosomal acidification by activating Nox2 to potentiate chemotherapy-induced apoptosis via the ROS-MAPK pathway in human lung carcinoma cells by Zhan, Yujuan, Chen, Qiugu, Song, Yue, Wei, Xianli, Zhao, Tingxiu, Chen, Bonan, Li, Chengxi, Zhang, Wenbo, Jiang, Yanjun, Tan, Yuhui, Du, Biaoyan, Xiao, Jianyong, Wang, Kun

“…Autophagy is typically activated in cancer cells as a rescue strategy in response to cellular stress (e.g., chemotherapy). Herein, we found that Berbamine…”
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