Search Results - "Du, Ailing"
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Improved gene therapy for spinal muscular atrophy in mice using codon-optimized hSMN1 transgene and hSMN1 gene-derived promotor
Published in EMBO molecular medicine (15-04-2024)“…Physiological regulation of transgene expression is a major challenge in gene therapy. Onasemnogene abeparvovec ( Zolgensma ® ) is an approved adeno-associated…”
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2
Non-canonical amino acid incorporation into AAV5 capsid enhances lung transduction in mice
Published in Molecular therapy. Methods & clinical development (14-12-2023)“…Gene therapy using recombinant adeno-associated virus (rAAV) relies on safe, efficient, and precise in vivo gene delivery that is largely dependent on the AAV…”
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3
Producing high-quantity and high-quality recombinant adeno-associated virus by low-cis triple transfection
Published in Molecular therapy. Methods & clinical development (13-06-2024)“…Recombinant adeno-associated virus (rAAV)-based gene therapy is entering clinical and commercial stages at an unprecedented pace. Triple transfection of HEK293…”
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4
Base editing rescue of spinal muscular atrophy in cells and in mice
Published in Science (American Association for the Advancement of Science) (21-04-2023)“…Spinal muscular atrophy (SMA), the leading genetic cause of infant mortality, arises from survival motor neuron (SMN) protein insufficiency resulting from…”
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5
Biodegradable porous polymeric drug as a drug delivery system: alleviation of doxorubicin-induced cardiotoxicity via passive targeted release
Published in RSC advances (06-02-2023)“…Doxorubicin (DOX) is an effective chemotherapeutic drug developed against a broad range of cancers, and its clinical applications are greatly restricted by the…”
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6
Foxg1 Directly Represses Dbx1 to Confine the POA and Subsequently Regulate Ventral Telencephalic Patterning
Published in Cerebral cortex (New York, N.Y. 1991) (17-12-2019)“…Abstract During early development, signaling centers, such as the cortical hem and the preoptic area (POA), are critical for telencephalic patterning. However,…”
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7
Reliability analysis of turbine-driven auxiliary feedwater pump of a nuclear power plant
Published in 2016 11th International Conference on Reliability, Maintainability and Safety (ICRMS) (01-10-2016)“…This study analyzed the process of reliability assessment for a turbine-driven auxiliary feedwater (AFW) pump according to the date of a domestic nuclear power…”
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Conference Proceeding -
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Analysis of volatile oil of garlic by gas chromatography-mass spectrometry
Published in Sepu (01-09-2005)“…The volatile oil of garlic was extracted by hydrodistillation method and gas chromatography-mass spectrometry was applied to analyse the compounds in the oil…”
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Journal Article -
9
Systemic gene therapy corrects the neurological phenotype in a mouse model of NGLY1 deficiency
Published in JCI insight (08-10-2024)“…The cytoplasmic peptide:N-glycanase (NGLY1) is ubiquitously expressed and functions as a de-N-glycosylating enzyme that degrades misfolded N-glycosylated…”
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10
Analysis of water leaching and transition processes in zirconium oxychloride octahydrate production
Published in Ceramics international (01-01-2014)“…The water leaching and transition process in manufacturing zirconium oxychloride octahydrate was examined. Results from X-ray diffraction (XRD) and…”
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A novel function for Foxm1 in interkinetic nuclear migration in the developing telencephalon and anxiety-related behavior
Published in The Journal of neuroscience (22-01-2014)“…Interkinetic nuclear migration (INM) is a key feature of cortical neurogenesis. INM functions to maximize the output of the neuroepithelium, and more…”
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12
Biodegradable porous polymeric drug as a drug delivery system: alleviation of doxorubicin-induced cardiotoxicity passive targeted release
Published in RSC advances (13-02-2023)“…Doxorubicin (DOX) is an effective chemotherapeutic drug developed against a broad range of cancers, and its clinical applications are greatly restricted by the…”
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Journal Article -
13
Removal of silicon in acid leaching and flocculation processes during zirconium oxychloride octahydrate production
Published in Ceramics international (01-07-2014)“…The efficiency of silicon removal technology by acid leaching and flocculation during zirconium oxychloride octahydrate (ZrOCl2⋅8H2O) production has been…”
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14
Investigation of P300 evoked by Stroop Color Word Task in children with emotional neglect
Published in Sichuan Jingshen Weisheng (01-02-2022)“…ObjectiveTo investigate the P300 evoked by Stroop Color Word Task in children with emotional neglect, and to explore their implication for inhibition control…”
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15
Construction of teaching case base for postgraduates majoring in psychiatry and mental health
Published in Sichuan Jingshen Weisheng (01-01-2019)“…This paper aims to explore the construction of master's degree graduate students of psychiatry and mental health professional (MDPM) teaching case base. With…”
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Application of flipped classroom clinical teaching mode in clinical probation teaching of psychiatry department
Published in Sichuan Jingshen Weisheng (01-04-2021)“…ObjectiveTo explore the effect of flipped classroom mode in the clinical probation teaching for undergraduate mental health students, so as to expand the new…”
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Journal Article -
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Evaluation of teaching case database for professional degree postgraduates majoring in psychiatry and mental health
Published in Sichuan Jingshen Weisheng (01-01-2019)“…ObjectiveTo evaluate the application value of established teaching case database for professional degree postgraduates majoring in psychiatry and mental…”
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Journal Article