Search Results - "Drzymalski, Marzena"
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Dysferlin mediates membrane tubulation and links T-tubule biogenesis to muscular dystrophy
Published in Journal of cell science (01-03-2017)“…The multi-C2 domain protein dysferlin localizes to the plasma membrane and the T-tubule system in skeletal muscle; however, its physiological mode of action is…”
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2
Generation of highly purified human cardiomyocytes from peripheral blood mononuclear cell-derived induced pluripotent stem cells
Published in PloS one (13-05-2015)“…Induced pluripotent stem (iPS) cells have an enormous potential for physiological studies. A novel protocol was developed combining the derivation of iPS from…”
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3
Postoperative complications after elective coronary artery bypass grafting surgery in patients with sleep-disordered breathing
Published in Clinical research in cardiology (01-12-2018)“…Background Sleep-disordered breathing (SDB) may increase the risk of postoperative complications in patients after cardiac surgery. This study evaluated the…”
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4
SAR296968, a Novel Selective Na+/Ca2+ Exchanger Inhibitor, Improves Ca2+ Handling and Contractile Function in Human Atrial Cardiomyocytes
Published in Biomedicines (09-08-2022)“…Background: In reverse-mode, cardiac sodium-calcium exchanger (NCX) can increase the cytoplasmic Ca2+ concentration in response to high intracellular Na+…”
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5
Enhanced Cardiac CaMKII Oxidation and CaMKII-Dependent SR Ca Leak in Patients with Sleep-Disordered Breathing
Published in Antioxidants (08-02-2022)“…Sleep-disordered breathing (SDB) is associated with increased oxidant generation. Oxidized Ca/calmodulin kinase II (CaMKII) can contribute to atrial…”
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The oral Ca/calmodulin‐dependent kinase II inhibitor RA608 improves contractile function and prevents arrhythmias in heart failure
Published in ESC Heart Failure (01-10-2020)“…Aims Excessive activation of Ca/calmodulin‐dependent kinase II (CaMKII) is of critical importance in heart failure (HF) and atrial fibrillation. Unfortunately,…”
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7
SR Ca2+-leak and disordered excitation-contraction coupling as the basis for arrhythmogenic and negative inotropic effects of acute ethanol exposure
Published in Journal of molecular and cellular cardiology (01-03-2018)“…Ethanol has acute negative inotropic and arrhythmogenic effects. The underlying mechanisms, however, are largely unknown. Sarcoplasmic reticulum Ca2+-leak is…”
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SAR296968, a Novel Selective Na[sup.+]/Ca[sup.2+] Exchanger Inhibitor, Improves Ca[sup.2+] Handling and Contractile Function in Human Atrial Cardiomyocytes
Published in Biomedicines (01-08-2022)“…Background: In reverse-mode, cardiac sodium-calcium exchanger (NCX) can increase the cytoplasmic Ca[sup.2+] concentration in response to high intracellular…”
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Journal Article -
9
SR Ca 2+ -leak and disordered excitation-contraction coupling as the basis for arrhythmogenic and negative inotropic effects of acute ethanol exposure
Published in Journal of molecular and cellular cardiology (01-03-2018)“…Ethanol has acute negative inotropic and arrhythmogenic effects. The underlying mechanisms, however, are largely unknown. Sarcoplasmic reticulum Ca -leak is an…”
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Journal Article -
10
Generation of Highly Purified Human Cardiomyocytes from Peripheral Blood Mononuclear Cell-Derived Induced Pluripotent Stem Cells: e0126596
Published in PloS one (01-05-2015)“…Induced pluripotent stem (iPS) cells have an enormous potential for physiological studies. A novel protocol was developed combining the derivation of iPS from…”
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11
Abstract 15705: Disordered Excitation Contraction Coupling as the Basis for Arrhythmogenic and Negative Inotropic Effects of Acute Ethanol Exposure
Published in Circulation (New York, N.Y.) (11-11-2016)“…RationaleEthanol (EtOH) acutely has negative inotropic and arrhythmogenic effects, but the mechanisms for this are largely unknown. We speculated that EtOH…”
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