Search Results - "Drynda, Robert"
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The Placental Secretome: Identifying Potential Cross-Talk Between Placenta and Islet β-Cells
Published in Cellular physiology and biochemistry (01-01-2018)“…Background/Aims: Insulin-secreting islet β-cells adapt to the insulin resistance associated with pregnancy by increasing functional β-cell mass, but the…”
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Journal Article -
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Nupr1 deletion protects against glucose intolerance by increasing beta cell mass
Published in Diabetologia (01-11-2013)“…Aims/hypothesis The stress-activated nuclear protein transcription regulator 1 (NUPR1) is induced in response to glucose and TNF-α, both of which are elevated…”
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Journal Article -
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Polycystic Kidney Disease with Hyperinsulinemic Hypoglycemia Caused by a Promoter Mutation in Phosphomannomutase 2
Published in Journal of the American Society of Nephrology (01-08-2017)“…Hyperinsulinemic hypoglycemia (HI) and congenital polycystic kidney disease (PKD) are rare, genetically heterogeneous disorders. The co-occurrence of these…”
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Journal Article -
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Strategies to increase β-cell mass expansion
Published 01-01-2017“…Aim: Failure of the functional β-cell mass to adapt to compensate for peripheral insulin resistance leads to the development of type 2 diabetes and gestational…”
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Dissertation