Search Results - "Druzhilovskiy, D S"

Computer-aided prediction of biological activity spectra for organic compounds: the possibilities and limitations by Poroikov, V. V., Filimonov, D. A., Gloriozova, T. A., Lagunin, A. A., Druzhilovskiy, D. S., Rudik, A. V., Stolbov, L. A., Dmitriev, A. V., Tarasova, O. A., Ivanov, S. M., Pogodin, P. V.

“…We describe the current version of the PASS program for prediction of biological activity spectra of organic compounds based on analysis of structure—activity…”
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How good are publicly available web services that predict bioactivity profiles for drug repurposing? by Murtazalieva, K. A., Druzhilovskiy, D. S., Goel, R. K., Sastry, G. N., Poroikov, V. V.

“…Drug repurposing provides a non-laborious and less expensive way for finding new human medicines. Computational assessment of bioactivity profiles shed light…”
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Ligand-based virtual screening and biological evaluation of inhibitors of Mycobacterium tuberculosis H37Rv by Pogodin, P.V., Salina, E.G., Semenov, V.V., Raihstat, M.M., Druzhilovskiy, D.S., Filimonov, D.A., Poroikov, V.V.

“…Novel antimycobacterial compounds are needed to expand the existing toolbox of therapeutic agents, which sometimes fail to be effective. In our study we…”
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Anti-inflammatory action of new hybrid N-acyl-[1,2]dithiolo-[3,4-c]quinoline-1-thione by Medvedeva, S.M., Petrou, A., Fesatidou, M., Gavalas, A., Geronikaki, A.A., Savosina, P.I., Druzhilovskiy, D.S., Poroikov, V.V., Shikhaliev, K.S., Kartsev, V.G.

“…Most of pharmaceutical agents display a number of biological activities. It is obvious that testing even one compound for thousands of biological activities is…”
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Computer-aided discovery of pleiotropic effects: Anti-inflammatory action of dithioloquinolinethiones as a case study by Medvedeva, S.M., Shikhaliev, K.S., Geronikaki, A.A., Savosina, P.I., Druzhilovskiy, D.S., Poroikov, V.V.

“…Most of pharmaceutical agents exhibit several or even many biological activities. It is clear that testing even one compound for thousands of biological…”
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Computational platform Way2Drug: from the prediction of biological activity to drug repurposing by Druzhilovskiy, D. S., Rudik, A. V., Filimonov, D. A., Gloriozova, T. A., Lagunin, A. A., Dmitriev, A. V., Pogodin, P. V., Dubovskaya, V. I., Ivanov, S. M., Tarasova, O. A., Bezhentsev, V. M., Murtazalieva, K. A., Semin, M. I., Maiorov, I. S., Gaur, A. S., Sastry, G. N., Poroikov, V. V.

“…The Way2Drug informational-computational platform (www.way2drug.com/dr) provides access to the data on drugs approved for medicinal use in the USA and Russian…”
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In Silico Estimation of the Safety of Pharmacologically Active Substances Using Machine Learning Methods: A Review by Poroikov, V. V., Dmitriev, A. V., Druzhilovskiy, D. S., Ivanov, S. M., Lagunin, A. A., Pogodin, P. V., Rudik, A. V., Savosina, P. I., Tarasova, O.  A., Filimonov, D. A.

“…Scientific relevance. Currently, machine learning (ML) methods are widely used in the research and development of new pharmaceuticals. ML methods are…”
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Online resources for the prediction of biological activity of organic compounds by Druzhilovskiy, D. S., Rudik, A. V., Filimonov, D. A., Lagunin, A. A., Gloriozova, T. A., Poroikov, V. V.

“…Online resources (PASS Online, SuperPred, SwissTargetPrediction and DRAR-CPI) for the prediction of biological activity of organic compounds from their…”
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Discovering new antiretroviral compounds in "Big Data" chemical space of the SAVI library by Savosina, P I, Stolbov, L A, Druzhilovskiy, D S, Filimonov, D A, Nicklaus, M C, Poroikov, V V

“…Despite significant advances in the application of highly active antiretroviral therapy, the development of new drugs for the treatment of HIV infection…”
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Quality control study of engineered skin tissue by Nakhod, K V, Rusanov, A L, Luzgina, E D, Druzhilovskiy, D S, Luzgina, N G, Lisitsa, A V

“…OMERO service was used to annotate the cell line HaCaT microscope images by two independent expert groups. The images were obtained in the course of developing…”
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