Search Results - "Druzak, Samuel"

Refrigeration-Induced Binding of von Willebrand Factor Facilitates Fast Clearance of Refrigerated Platelets by Chen, Wenchun, Druzak, Samuel A, Wang, Yingchun, Josephson, Cassandra D, Hoffmeister, Karin M, Ware, Jerry, Li, Renhao

“…OBJECTIVE—Apheresis platelets for transfusion treatment are currently stored at room temperature because after refrigeration platelets are rapidly cleared on…”
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Ligand dependent interaction between PC-TP and PPARδ mitigates diet-induced hepatic steatosis in male mice by Druzak, Samuel A., Tardelli, Matteo, Mays, Suzanne G., El Bejjani, Mireille, Mo, Xulie, Maner-Smith, Kristal M., Bowen, Thomas, Cato, Michael L., Tillman, Matthew C., Sugiyama, Akiko, Xie, Yang, Fu, Haian, Cohen, David E., Ortlund, Eric A.

“…Phosphatidylcholine transfer protein (PC-TP; synonym StarD2) is a soluble lipid-binding protein that transports phosphatidylcholine (PC) between cellular…”
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SAT-LB124 Phosphatidylcholine Transfer Protein Interacts With PPARδ to Modulate Activity by Druzak, Samuel Adam, Mays, Suzanne, Ortlund, Eric

“…Obesity is one of the largest public health crises in the USA. Obesity can be lethal due to the development of cardiovascular complications such as,…”
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Multiplatform analyses reveal distinct drivers of systemic pathogenesis in adult versus pediatric severe acute COVID-19 by Druzak, Samuel, Iffrig, Elizabeth, Roberts, Blaine R., Zhang, Tiantian, Fibben, Kirby S., Sakurai, Yumiko, Verkerke, Hans P., Rostad, Christina A., Chahroudi, Ann, Schneider, Frank, Wong, Andrew Kam Ho, Roberts, Anne M., Chandler, Joshua D., Kim, Susan O., Mosunjac, Mario, Mosunjac, Marina, Geller, Rachel, Albizua, Igor, Stowell, Sean R., Arthur, Connie M., Anderson, Evan J., Ivanova, Anna A., Ahn, Jun, Liu, Xueyun, Maner-Smith, Kristal, Bowen, Thomas, Paiardini, Mirko, Bosinger, Steve E., Roback, John D., Kulpa, Deanna A., Silvestri, Guido, Lam, Wilbur A., Ortlund, Eric A., Maier, Cheryl L.

“…The pathogenesis of multi-organ dysfunction associated with severe acute SARS-CoV-2 infection remains poorly understood. Endothelial damage and microvascular…”
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A discontinuous autoinhibitory module masks the A1 domain of von Willebrand factor by Deng, W., Wang, Y., Druzak, S. A., Healey, J. F., Syed, A. K., Lollar, P., Li, R.

“…Essentials The mechanism for the auto‐inhibition of von Willebrand factor (VWF) remains unclear. Hydrogen exchange of two VWF A1 fragments with disparate…”
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PMON184 Ligand-dependent interaction between phosphatidylcholine transfer protein and PPARδ: therapeutic implications for metabolic syndrome by Druzak, Samuel, Tardelli, Matteo, Mays, Suzanne, Bejjani, Mireille, Cato, Micheal, Tillman, Matthew, Cohen, David, Mo, Xiulei, Fu, Haian

“…Phosphatidylcholine transfer protein (PC-TP; synonym StarD2) is a soluble lipid binding protein that transports phosphatidylcholine (PC) between cellular…”
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Microbial metabolite delta-valerobetaine is a diet-dependent obesogen by Liu, Ken H., Owens, Joshua A., Saeedi, Bejan, Cohen, Catherine E., Bellissimo, Moriah P., Naudin, Crystal, Darby, Trevor, Druzak, Samuel, Maner-Smith, Kristal, Orr, Michael, Hu, Xin, Fernandes, Jolyn, Camacho, Mary Catherine, Hunter-Chang, Sarah, VanInsberghe, David, Ma, Chunyu, Ganesh, Thota, Yeligar, Samantha M., Uppal, Karan, Go, Young-Mi, Alvarez, Jessica A., Vos, Miriam B., Ziegler, Thomas R., Woodworth, Michael H., Kraft, Colleen S., Jones, Rheinallt M., Ortlund, Eric, Neish, Andrew S., Jones, Dean P.

“…Obesity and obesity-related metabolic disorders are linked to the intestinal microbiome. However, the causality of changes in the microbiome–host interaction…”
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