Clinical characteristics and outcomes of in-hospital cardiac arrest among patients with and without COVID-19

To define outcomes of patients with COVID-19 compared to patients without COVID-19 suffering in-hospital cardiac arrest (IHCA). We performed a single-center retrospective study of IHCA cases. Patients with COVID-19 were compared to consecutive patients without COVID-19 from the prior year. Return of...

Full description

Saved in:

Bibliographic Details
Published in:	Resuscitation plus Vol. 4; p. 100054
Main Authors:	Yuriditsky, Eugene, Mitchell, Oscar J.L., Brosnahan, Shari B., Smilowitz, Nathaniel R., Drus, Karsten W., Gonzales, Anelly M., Xia, Yuhe, Parnia, Sam, Horowitz, James M.
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier B.V 01-12-2020 Elsevier
Subjects:	Cardiac arrest Cardiopulmonary resuscitation Clinical Paper COVID-19 ROSC HLD HTN CAD Cardiac arrest DNR ROSC PEA COVID-19 VF OHCA Cardiopulmonary resuscitation CPC AHA CKD VT IHCA PEA, Pulseless electrical activity CKD, Chronic kidney disease CPC, Cerebral performance category VT, Ventricular tachycardia AHA, American Heart Association COVID-19, Coronavirus disease 2019 OHCA, Out-of-hospital cardiac arrest VF, Ventricular fibrillation HLD, Hyperlipidemia IHCA, In-hospital cardiac arrest ROSC, Return of spontaneous circulation CAD, Coronary artery disease DNR, Do not resuscitate HTN, Hypertension
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	To define outcomes of patients with COVID-19 compared to patients without COVID-19 suffering in-hospital cardiac arrest (IHCA). We performed a single-center retrospective study of IHCA cases. Patients with COVID-19 were compared to consecutive patients without COVID-19 from the prior year. Return of spontaneous circulation (ROSC), 30-day survival, and cerebral performance category (CPC) at 30-days were assessed. Fifty-five patients with COVID-19 suffering IHCA were identified and compared to 55 consecutive IHCA patients in 2019. The COVID-19 cohort was more likely to require vasoactive agents (67.3% v 32.7%, p=0.001), invasive mechanical ventilation (76.4% v 23.6%, p<0.001), renal replacement therapy (18.2% v 3.6%, p=0.029) and intensive care unit care (83.6% v 50.9%, p=0.001) prior to IHCA. Patients with COVID-19 had shorter CPR duration (10min v 22min, p=0.002). ROSC (38.2% v 49.1%, p=0.336) and 30-day survival (20% v 32.7%, p=0.194) did not differ. A 30-day cerebral performance category of 1 or 2 was more common among non-COVID patients (27.3% v 9.1%, p=0.048). Return of spontaneous circulation and 30-day survival were similar between IHCA patients with and without COVID-19. Compared to previously published data, we report greater ROSC and 30-day survival after IHCA in COVID-19.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	2666-5204 2666-5204
DOI:	10.1016/j.resplu.2020.100054