Search Results - "Drummond, J. C."
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The lower limit of autoregulation: time to revise our thinking?
Published in Anesthesiology (Philadelphia) (01-06-1997)Get full text
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Incompatible effects of p53 and HDAC inhibition on p21 expression and cell cycle progression
Published in Cell death & disease (01-03-2013)“…Nutlin-3 selectively activates p53 by inhibiting the interaction of this tumor suppressor with its negative regulator murine double minute 2 (mdm2), while…”
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Direct Force Measurements between Silica and Alumina
Published in Langmuir (02-04-1997)“…AFM force measurements were carried out between a silica colloid sphere and an alumina flat crystal over a wide pH range and in both 1 × 10-4 and 1 × 10-3 M…”
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Isoflurane delays but does not prevent cerebral infarction in rats subjected to focal ischemia
Published in Anesthesiology (Philadelphia) (01-05-2000)“…Several investigations have shown that volatile anesthetics can reduce ischemic cerebral injury. In these studies, however, neurologic injury was evaluated…”
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Transplantation of rat synapsin-EGFP-labeled embryonic neurons into the intact and ischemic CA1 hippocampal region: distribution, phenotype, and axodendritic sprouting
Published in Cell transplantation (01-01-2011)“…A major limitation of neural transplantation studies is assessing the degree of host-graft interaction. In the present study, rat hippocampal/cortical…”
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The effect of the reduction of colloid oncotic pressure, with and without reduction of osmolality, on post-traumatic cerebral edema
Published in Anesthesiology (Philadelphia) (01-04-1998)“…It has been asserted that reduction of colloid oncotic pressure (COP) can aggravate traumatic brain edema. To explore this issue, the authors measured the…”
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Isoflurane reduces N-methyl-D-aspartate toxicity in vivo in the rat cerebral cortex
Published in Anesthesia and analgesia (01-12-1999)“…Recent in vitro data indicate that isoflurane can reduce N-methyl-D-aspartate (NMDA) receptor-mediated responses and thereby might reduce excitotoxicity…”
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Effects of propofol, etomidate, midazolam, and fentanyl on motor evoked responses to transcranial electrical or magnetic stimulation in humans
Published in Anesthesiology (Philadelphia) (01-04-1992)“…The effects of propofol, etomidate, midazolam, and fentanyl on motor evoked responses to transcranial stimulation (tc-MERs) were studied in five healthy human…”
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Isoflurane and pentobarbital reduce AMPA toxicity in vivo in the rat cerebral cortex
Published in Anesthesiology (Philadelphia) (01-03-2000)“…Isoflurane and pentobarbital can reduce alpha-amino-d-hydroxy-5-methyl-4-isoxazole-propionate (AMPA) receptor-mediated toxicity in vitro. However, their effect…”
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Improved amplitude of myogenic motor evoked responses after paired transcranial electrical stimulation during sufentanil/nitrous oxide anesthesia
Published in Anesthesiology (Philadelphia) (01-08-1995)“…Measurement of motor evoked responses to transcranial stimulation (tc-MER) is a technique for intraoperative monitoring of motor pathways in the brain and…”
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Isoflurane reduces ischemia-induced glutamate release in rats subjected to forebrain ischemia
Published in Anesthesiology (Philadelphia) (01-04-1995)“…The release of excitatory neurotransmitters during ischemia is thought to contribute to ischemic neuronal injury. Volatile anesthetics have been shown to…”
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Fentanyl does not increase brain injury after focal cerebral ischemia in rats
Published in Anesthesia and analgesia (1999)“…Recent reports have indicated that large-dose opiate anesthesia can increase neuronal injury in rats subjected to forebrain ischemia. However, most episodes of…”
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Isoflurane and pentobarbital reduce the frequency of transient ischemic depolarizations during focal ischemia in rats
Published in Anesthesia and analgesia (01-04-1998)“…Repetitive transient ischemic depolarizations (IDs) during focal cerebral ischemia are thought to contribute to ischemic damage. Isoflurane and pentobarbital…”
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A comparison of median frequency, spectral edge frequency, a frequency band power ratio, total power, and dominance shift in the determination of depth of anesthesia
Published in Acta anaesthesiologica Scandinavica (01-11-1991)“…Five numerical descriptors were derived from the electroencephalogram (EEG), recorded, and processed (Tracor Nomad) during emergence from isoflurane-nitrous…”
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A comparison of the cerebral protective effects of isoflurane and mild hypothermia in a model of incomplete forebrain ischemia in the rat
Published in Anesthesiology (Philadelphia) (01-02-1992)“…The present study was undertaken to examine the cerebral protective properties attributed to isoflurane and at the same time to compare its protective effects…”
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MAC for halothane, enflurane, and isoflurane in the New Zealand white rabbit: and a test for the validity of MAC determinations
Published in Anesthesiology (Philadelphia) (01-01-1985)“…MAC determinations for halothane, enflurane, and isoflurane were performed in New Zealand white rabbits (n = 8, approximate age 6 months). The MAC values…”
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Temporary focal cerebral ischemia in spontaneously hypertensive rats: the effect of ibuprofen on infarct volume
Published in The Journal of pharmacology and experimental therapeutics (01-09-1993)“…Arachidonic acid metabolism results in the generation of oxygen radicals and production of prostanoids which are proposed to adversely influence cerebral…”
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Intraoperative monitoring of tibialis anterior muscle motor evoked responses to transcranial electrical stimulation during partial neuromuscular blockade
Published in Anesthesia and analgesia (01-10-1992)“…We studied the feasibility of recording motor evoked responses to transcranial electrical stimulation (tce-MERs) during partial neuromuscular blockade (NMB)…”
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Differential effects of nitrous oxide and propofol on myogenic transcranial motor evoked responses during sufentanil anaesthesia
Published in British Journal of Anaesthesia (01-11-1997)“…We have compared the effects of 50% nitrous oxide and propofol, each administered concurrently with sufentanil, on the amplitudes and latencies of the compound…”
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Journal Article Conference Proceeding