Search Results - "Drumm, Jeffrey"
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Adenylyl cyclase increases survival in cardiomyopathy
Published in Circulation (New York, N.Y.) (23-04-2002)“…To test the hypothesis that increased cardiac adenylyl cyclase type VI (AC(VI)) content, which results in increased cAMP generation, would increase survival in…”
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Myocardial gene transfer and long-term expression following intracoronary delivery of adeno-associated virus
Published in The journal of gene medicine (01-03-2005)“…Adeno‐associated viral vectors (AAV) can direct long‐term gene expression in post‐mitotic cells. Previous studies have established that long‐term cardiac gene…”
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3
Cardiac-directed expression of adenylyl cyclase and heart rate regulation
Published in Basic research in cardiology (01-11-2003)“…Mice with cardiac-directed overexpression of AC(VI) show increased cardiac responsiveness to beta-adrenergic receptor stimulation but regulation of heart rate…”
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Natriuretic peptide gene expression after beta-adrenergic stimulation in adult mouse cardiac myocytes
Published in DNA and cell biology (01-09-2004)“…The role of A- and B-type natriuretic peptides (ANP and BNP) in cardiac pathophysiology are of increasing interest. Isolated neonatal mouse cardiac myocytes…”
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Adenylyl cyclase type V deletion increases basal left ventricular function and reduces left ventricular contractile responsiveness to beta-adrenergic stimulation
Published in Basic research in cardiology (01-03-2006)“…We tested the hypothesis that deletion of adenylyl cyclase type V (AC(V)) would be associated with decreased left ventricular (LV) contractile function and…”
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6
Controlled expression of cardiac-directed adenylylcyclase type VI provides increased contractile function
Published in Cardiovascular research (01-11-2002)“…We have previously shown that cardiac-directed expression of adenylycyclase type VI (AC(VI)) increases heart function in transgenic mice, and improves heart…”
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