Search Results - "Drugs in R & D (Online)"

A Guide to Medications Inducing Salivary Gland Dysfunction, Xerostomia, and Subjective Sialorrhea: A Systematic Review Sponsored by the World Workshop on Oral Medicine VI by Wolff, Andy, Joshi, Revan Kumar, Ekström, Jörgen, Aframian, Doron, Pedersen, Anne Marie Lynge, Proctor, Gordon, Narayana, Nagamani, Villa, Alessandro, Sia, Ying Wai, Aliko, Ardita, McGowan, Richard, Kerr, Alexander Ross, Jensen, Siri Beier, Vissink, Arjan, Dawes, Colin

“…Background Medication-induced salivary gland dysfunction (MISGD), xerostomia (sensation of oral dryness), and subjective sialorrhea cause significant morbidity…”
Get full text

An Updated Overview on Therapeutic Drug Monitoring of Recent Antiepileptic Drugs by Jacob, Shery, Nair, Anroop B.

“…Given the distinctive characteristics of both epilepsy and antiepileptic drugs (AEDs), therapeutic drug monitoring (TDM) can make a significant contribution to…”
Get full text

Salvia (Sage): A Review of its Potential Cognitive-Enhancing and Protective Effects by Lopresti, Adrian L.

“…Genus Salvia , commonly known as sage, is the largest genus in the Lamiaceae family. It comprises many species traditionally used as brain-enhancing tonics. In…”
Get full text

Second-Generation Antipsychotics and Neuroleptic Malignant Syndrome: Systematic Review and Case Report Analysis by Belvederi Murri, Martino, Guaglianone, Argentina, Bugliani, Michele, Calcagno, Pietro, Respino, Matteo, Serafini, Gianluca, Innamorati, Marco, Pompili, Maurizio, Amore, Mario

“…Background Neuroleptic malignant syndrome (NMS) is a rare, severe, idiosyncratic adverse reaction to antipsychotics. Second-generation antipsychotics (SGAs)…”
Get full text

Comparative Pharmacology of Risperidone and Paliperidone by Corena-McLeod, Maria

“…Antipsychotics, risperidone, and risperidone’s active metabolite, paliperidone (9-hydroxyrisperidone), are related molecules used for the treatment of…”
Get full text

Ketamine as a Potential Treatment for Suicidal Ideation: A Systematic Review of the Literature by Reinstatler, Lael, Youssef, Nagy A.

“…Objective To review the published literature on the efficacy of ketamine for the treatment of suicidal ideation (SI). Methods The PubMed and Cochrane databases…”
Get full text

Molecular Insight in the Multifunctional Effects of Oridonin by Owona, Brice Ayissi, Schluesener, Herman J.

“…Oridonin has attracted considerable attention in the last decade because of its anti-cancer pharmacological properties. This ent-kaurane diterpenoid, isolated…”
Get full text

Efficacy of Immunobiologic and Small Molecule Inhibitor Drugs for Psoriasis: A Systematic Review and Meta-Analysis of Randomized Clinical Trials by de Carvalho, André Vicente Esteves, Duquia, Rodrigo Pereira, Horta, Bernardo Lessa, Bonamigo, Renan Rangel

“…Background Psoriasis is an immune-mediated inflammatory disease for which treatment has evolved over the past few years due to the introduction of…”
Get full text

Lithium in Bipolar Disorder: Optimizing Therapy Using Prolonged-Release Formulations by Girardi, Paolo, Brugnoli, Roberto, Manfredi, Giovanni, Sani, Gabriele

“…Lithium has been a gold standard in the treatment of bipolar disorder (BD) for several decades. Despite a general reduction in the use of lithium over the past…”
Get full text

Imeglimin: A Potential New Multi-Target Drug for Type 2 Diabetes by Vuylsteke, Valerie, Chastain, Lisa M., Maggu, Geeta A., Brown, Crystal

“…Imeglimin is a novel agent currently in development to treat type 2 diabetes. Laboratory studies have demonstrated that it has the potential to impact the…”
Get full text

A Review of Clinical Outcomes Associated with Two Meropenem Dosing Strategies by Wilby, Kyle John, Nasr, Ziad Ghantous, Elazzazy, Shereen, Lau, Tim T. Y., Hamad, Anas

“…Meropenem is a carbapenem antibiotic that exhibits time-dependent bactericidal activity, traditionally dosed intravenously at 1 g every 8 h. In order to…”
Get full text