Search Results - "Drug safety"

Cardiac Complications Attributed to Chloroquine and Hydroxychloroquine: A Systematic Review of the Literature by Chatre, Clotilde, Roubille, François, Vernhet, Hélène, Jorgensen, Christian, Pers, Yves-Marie

“…Introduction Chloroquine and hydroxychloroquine are widely used in the long-term treatment of connective tissue disease and usually considered safe. However,…”
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COVID-19 Vaccination in Pregnancy, Paediatrics, Immunocompromised Patients, and Persons with History of Allergy or Prior SARS-CoV-2 Infection: Overview of Current Recommendations and Pre- and Post-Marketing Evidence for Vaccine Efficacy and Safety by Luxi, Nicoletta, Giovanazzi, Alexia, Capuano, Annalisa, Crisafulli, Salvatore, Cutroneo, Paola Maria, Fantini, Maria Pia, Ferrajolo, Carmen, Moretti, Ugo, Poluzzi, Elisabetta, Raschi, Emanuel, Ravaldi, Claudia, Reno, Chiara, Tuccori, Marco, Vannacci, Alfredo, Zanoni, Giovanna, Trifirò, Gianluca

“…To date, four vaccines have been authorised for emergency use and under conditional approval by the European Medicines Agency to prevent COVID-19: Comirnaty,…”
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Prevalence and Nature of Medication Errors and Medication-Related Harm Following Discharge from Hospital to Community Settings: A Systematic Review by Alqenae, Fatema A., Steinke, Douglas, Keers, Richard N.

“…Background Little is known about the epidemiology of medication errors and medication-related harm following transition from secondary to primary care. This…”
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Epidemiology of Adverse Drug Reactions in Europe: A Review of Recent Observational Studies by Bouvy, Jacoline C., De Bruin, Marie L., Koopmanschap, Marc A.

“…Adverse drug reactions (ADRs) cause considerable mortality and morbidity but no recent reviews are currently available for the European region. Therefore, we…”
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Azithromycin in COVID-19 Patients: Pharmacological Mechanism, Clinical Evidence and Prescribing Guidelines by Sultana, Janet, Cutroneo, Paola Maria, Crisafulli, Salvatore, Puglisi, Gabriele, Caramori, Gaetano, Trifirò, Gianluca

“…The global COVID-19 pandemic has led to a race to find medications that can improve the prognosis of the disease. Azithromycin, in association with…”
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Comparative Safety of Vaccine Adjuvants: A Summary of Current Evidence and Future Needs by Petrovsky, Nikolai

“…Use of highly pure antigens to improve vaccine safety has led to reduced vaccine immunogenicity and efficacy. This has led to the need to use adjuvants to…”
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Sirolimus and mTOR Inhibitors: A Review of Side Effects and Specific Management in Solid Organ Transplantation by Nguyen, Lee S., Vautier, Mathieu, Allenbach, Yves, Zahr, Noel, Benveniste, Olivier, Funck-Brentano, Christian, Salem, Joe-Elie

“…Inhibitors of mechanistic target of rapamycin (mTOR inhibitors) are used as antiproliferative immunosuppressive drugs and have many clinical applications in…”
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Clinical Trial and Postmarketing Safety of Onasemnogene Abeparvovec Therapy by Day, John W., Mendell, Jerry R., Mercuri, Eugenio, Finkel, Richard S., Strauss, Kevin A., Kleyn, Aaron, Tauscher-Wisniewski, Sitra, Tukov, Francis Fonyuy, Reyna, Sandra P., Chand, Deepa H.

“…Introduction This is the first description of safety data for intravenous onasemnogene abeparvovec, the only approved systemically administered…”
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Prevalence and Nature of Medication Errors and Preventable Adverse Drug Events in Paediatric and Neonatal Intensive Care Settings: A Systematic Review by Alghamdi, Anwar A., Keers, Richard N., Sutherland, Adam, Ashcroft, Darren M.

“…Introduction Children admitted to paediatric and neonatal intensive care units may be at high risk from medication errors and preventable adverse drug events…”
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Overview of the First Natural Language Processing Challenge for Extracting Medication, Indication, and Adverse Drug Events from Electronic Health Record Notes (MADE 1.0) by Jagannatha, Abhyuday, Liu, Feifan, Liu, Weisong, Yu, Hong

“…Introduction This work describes the Medication and Adverse Drug Events from Electronic Health Records (MADE 1.0) corpus and provides an overview of the MADE…”
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Long-Term Safety and Efficacy of Fecal Microbiota Transplant in Active Ulcerative Colitis by Ding, Xiao, Li, Qianqian, Li, Pan, Zhang, Ting, Cui, Bota, Ji, Guozhong, Lu, Xiang, Zhang, Faming

“…Introduction and objective The therapeutic role of fecal microbiota transplantation in ulcerative colitis varies across different reports. This study aims to…”
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Causes of Medication Administration Errors in Hospitals: a Systematic Review of Quantitative and Qualitative Evidence by Keers, Richard N., Williams, Steven D., Cooke, Jonathan, Ashcroft, Darren M.

“…Background Underlying systems factors have been seen to be crucial contributors to the occurrence of medication errors. By understanding the causes of these…”
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Thromboembolism with Janus Kinase (JAK) Inhibitors for Rheumatoid Arthritis: How Real is the Risk? by Scott, Ian C., Hider, Samantha L., Scott, David L.

“…Two different Janus kinase (JAK) inhibitors—baricitinib and tofacitinib—are effective and licensed in active rheumatoid arthritis (RA). There have been recent…”
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Drug-Induced Liver Injury and COVID-19 Infection: The Rules Remain the Same by Olry, Alexandre, Meunier, Lucy, Délire, Bénédicte, Larrey, Dominique, Horsmans, Yves, Le Louët, Hervé

“…Olry et al examine the association of COVID-19 infection with liver abnormalities. Studies from China showed an increase of transaminases and other liver…”
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Second-Generation Antipsychotics and Metabolic Side Effects: A Systematic Review of Population-Based Studies by Hirsch, Lauren, Yang, Jaeun, Bresee, Lauren, Jette, Nathalie, Patten, Scott, Pringsheim, Tamara

“…Introduction There is strong evidence from randomized controlled trials (RCTs) that second-generation antipsychotic (SGA) medications are associated with…”
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Safety and Tolerability of Histone Deacetylase (HDAC) Inhibitors in Oncology by Shah, Rashmi R.

“…Histone deacetylases (HDACs) are expressed at increased levels in cells of various malignancies, and the use of HDAC inhibitors has improved outcomes in…”
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Natural Language Processing for EHR-Based Pharmacovigilance: A Structured Review by Luo, Yuan, Thompson, William K., Herr, Timothy M., Zeng, Zexian, Berendsen, Mark A., Jonnalagadda, Siddhartha R., Carson, Matthew B., Starren, Justin

“…The goal of pharmacovigilance is to detect, monitor, characterize and prevent adverse drug events (ADEs) with pharmaceutical products. This article is a…”
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Appropriate Polypharmacy and Medicine Safety: When Many is not Too Many by Cadogan, Cathal A., Ryan, Cristín, Hughes, Carmel M.

“…The use of multiple medicines (polypharmacy) is increasingly common in middle-aged and older populations. Ensuring the correct balance between the prescribing…”
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Disproportionality Analysis for Pharmacovigilance Signal Detection in Small Databases or Subsets: Recommendations for Limiting False-Positive Associations by Caster, Ola, Aoki, Yasunori, Gattepaille, Lucie M., Grundmark, Birgitta

“…Introduction Uncovering safety signals through the collection and assessment of individual case reports remains a core pharmacovigilance activity. Despite the…”
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Safety Surveillance of Traditional Chinese Medicine: Current and Future by Liu, Shwu-Huey, Chuang, Wu-Chang, Lam, Wing, Jiang, Zaoli, Cheng, Yung-Chi

“…Herbal medicine, including traditional Chinese medicine, has been used for the prevention, treatment, and cure of disorders or diseases for centuries. In…”
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