Search Results - "Druart, Celine"

A purified membrane protein from Akkermansia muciniphila or the pasteurized bacterium improves metabolism in obese and diabetic mice by Plovier, Hubert, Everard, Amandine, Druart, Céline, Depommier, Clara, Van Hul, Matthias, Geurts, Lucie, Chilloux, Julien, Ottman, Noora, Duparc, Thibaut, Lichtenstein, Laeticia, Myridakis, Antonis, Delzenne, Nathalie M, Klievink, Judith, Bhattacharjee, Arnab, van der Ark, Kees C H, Aalvink, Steven, Martinez, Laurent O, Dumas, Marc-Emmanuel, Maiter, Dominique, Loumaye, Audrey, Hermans, Michel P, Thissen, Jean-Paul, Belzer, Clara, de Vos, Willem M, Cani, Patrice D

“…Akkermansia muciniphila , a member of the gut microbiome, has been shown to improve metabolism in mice. Here it is reported that its pasteurization further…”
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Intestinal epithelial N-acylphosphatidylethanolamine phospholipase D links dietary fat to metabolic adaptations in obesity and steatosis by Everard, Amandine, Plovier, Hubert, Rastelli, Marialetizia, Van Hul, Matthias, de Wouters d’Oplinter, Alice, Geurts, Lucie, Druart, Céline, Robine, Sylvie, Delzenne, Nathalie M., Muccioli, Giulio G., de Vos, Willem M., Luquet, Serge, Flamand, Nicolas, Di Marzo, Vincenzo, Cani, Patrice D.

“…Variations in N -acylethanolamines (NAE) levels are associated with obesity and metabolic comorbidities. Their role in the gut remains unclear. Therefore, we…”
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Supplementation with Akkermansia muciniphila in overweight and obese human volunteers: a proof-of-concept exploratory study by Depommier, Clara, Everard, Amandine, Druart, Céline, Plovier, Hubert, Van Hul, Matthias, Vieira-Silva, Sara, Falony, Gwen, Raes, Jeroen, Maiter, Dominique, Delzenne, Nathalie M., de Barsy, Marie, Loumaye, Audrey, Hermans, Michel P., Thissen, Jean-Paul, de Vos, Willem M., Cani, Patrice D.

“…Metabolic syndrome is characterized by a constellation of comorbidities that predispose individuals to an increased risk of developing cardiovascular…”
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Dysosmobacter welbionis is a newly isolated human commensal bacterium preventing diet-induced obesity and metabolic disorders in mice by Le Roy, Tiphaine, Moens de Hase, Emilie, Van Hul, Matthias, Paquot, Adrien, Pelicaen, Rudy, Régnier, Marion, Depommier, Clara, Druart, Céline, Everard, Amandine, Maiter, Dominique, Delzenne, Nathalie M, Bindels, Laure B, de Barsy, Marie, Loumaye, Audrey, Hermans, Michel P, Thissen, Jean-Paul, Vieira-Silva, Sara, Falony, Gwen, Raes, Jeroen, Muccioli, Giulio G, Cani, Patrice D

“…To investigate the abundance and the prevalence of J115 , a novel butyrate-producing bacterium isolated from the human gut both in the general population and…”
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Hepatocyte MyD88 affects bile acids, gut microbiota and metabolome contributing to regulate glucose and lipid metabolism by Duparc, Thibaut, Plovier, Hubert, Marrachelli, Vannina G, Van Hul, Matthias, Essaghir, Ahmed, Ståhlman, Marcus, Matamoros, Sébastien, Geurts, Lucie, Pardo-Tendero, Mercedes M, Druart, Céline, Delzenne, Nathalie M, Demoulin, Jean-Baptiste, van der Merwe, Schalk W, van Pelt, Jos, Bäckhed, Fredrik, Monleon, Daniel, Everard, Amandine, Cani, Patrice D

“…To examine the role of hepatocyte myeloid differentiation primary-response gene 88 (MyD88) on glucose and lipid metabolism. To study the impact of the innate…”
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Reduced obesity, diabetes, and steatosis upon cinnamon and grape pomace are associated with changes in gut microbiota and markers of gut barrier by Van Hul, Matthias, Geurts, Lucie, Plovier, Hubert, Druart, Céline, Everard, Amandine, Ståhlman, Marcus, Rhimi, Moez, Chira, Kleopatra, Teissedre, Pierre-Louis, Delzenne, Nathalie M, Maguin, Emmanuelle, Guilbot, Angèle, Brochot, Amandine, Gérard, Philippe, Bäckhed, Fredrik, Cani, Patrice D

“…Increasing evidence suggests that polyphenols have a significant potential in the prevention and treatment of risk factors associated with metabolic syndrome…”
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Modulation of the Gut Microbiota by Nutrients with Prebiotic and Probiotic Properties by Druart, Céline, Alligier, Maud, Salazar, Nuria, Neyrinck, Audrey M., Delzenne, Nathalie M.

“…Experimental data in animals, but also observational studies in humans, suggest that the composition of the gut microbiota differs in obese vs. lean…”
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Gut Microbiome Integration in Drug Discovery and Development of Small Molecules by Jimonet, Patrick, Druart, Céline, Blanquet-Diot, Stéphanie, Boucinha, Lilia, Kourula, Stephanie, Le Vacon, Françoise, Maubant, Sylvie, Rabot, Sylvie, Van de Wiele, Tom, Schuren, Frank, Thomas, Vincent, Walther, Bernard, Zimmermann, Michael

“…Human microbiomes, particularly in the gut, could have a major impact on the efficacy and toxicity of drugs. However, gut microbial metabolism is often…”
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Ability of the gut microbiota to produce PUFA‐derived bacterial metabolites: Proof of concept in germ‐free versus conventionalized mice by Druart, Céline, Bindels, Laure B, Schmaltz, Robert, Neyrinck, Audrey M, Cani, Patrice D, Walter, Jens, Ramer‐Tait, Amanda E, Delzenne, Nathalie M

“…SCOPE: The gut microbiota is able to modulate host physiology through the production of bioactive metabolites. Our recent studies suggest that changes in gut…”
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Gut Microbial Metabolites of Polyunsaturated Fatty Acids Correlate with Specific Fecal Bacteria and Serum Markers of Metabolic Syndrome in Obese Women by Druart, Céline, Dewulf, Evelyne M., Cani, Patrice D., Neyrinck, Audrey M., Thissen, Jean-Paul, Delzenne, Nathalie M.

“…The aim of this human study was to assess the influence of prebiotic-induced gut microbiota modulation on PUFA-derived bacterial metabolites production…”
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Adipose tissue adaptive response to trans‐10, cis‐12‐conjugated linoleic acid engages alternatively activated M2 macrophages by Pini, Maria, Touch, Sothea, Poirier, Helene, Dalmas, Elise, Niot, Isabelle, Rouault, Christine, Druart, Celine, Delzenne, Nathalie, Clément, Karine, André, Sebastien, Guerre‐Millo, Michele

“…ABSTRACT In mice, nutritional supplementation with the trans‐10,cis‐12 isomer of linoleic acid (t10,c12‐CLA) promotes lipoatrophy, hyperinsulinemia, and…”
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Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity by Everard, Amandine, Belzer, Clara, Geurts, Lucie, Ouwerkerk, Janneke P., Druart, Céline, Bindels, Laure B., Guiot, Yves, Derrien, Muriel, Muccioli, Giulio G., Delzenne, Nathalie M., de Vos, Willem M., Cani, Patrice D.

“…Obesity and type 2 diabetes are characterized by altered gut microbiota, inflammation, and gut barrier disruption. Microbial composition and the mechanisms of…”
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Endocannabinoids — at the crossroads between the gut microbiota and host metabolism by Cani, Patrice D., Plovier, Hubert, Van Hul, Matthias, Geurts, Lucie, Delzenne, Nathalie M., Druart, Céline, Everard, Amandine

“…Key Points As gut microorganisms interact with host cells via several mechanisms, targeting the microbiota to treat metabolic disorders is an attractive…”
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Prebiotic effects of wheat arabinoxylan related to the increase in bifidobacteria, Roseburia and Bacteroides/Prevotella in diet-induced obese mice by Neyrinck, Audrey M, Possemiers, Sam, Druart, Céline, Van de Wiele, Tom, De Backer, Fabienne, Cani, Patrice D, Larondelle, Yvan, Delzenne, Nathalie M

“…Alterations in the composition of gut microbiota--known as dysbiosis--has been proposed to contribute to the development of obesity, thereby supporting the…”
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Adipose tissue NAPE-PLD controls fat mass development by altering the browning process and gut microbiota by Geurts, Lucie, Everard, Amandine, Van Hul, Matthias, Essaghir, Ahmed, Duparc, Thibaut, Matamoros, Sébastien, Plovier, Hubert, Castel, Julien, Denis, Raphael G. P., Bergiers, Marie, Druart, Céline, Alhouayek, Mireille, Delzenne, Nathalie M., Muccioli, Giulio G., Demoulin, Jean-Baptiste, Luquet, Serge, Cani, Patrice D.

“…Obesity is a pandemic disease associated with many metabolic alterations and involves several organs and systems. The endocannabinoid system (ECS) appears to…”
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Non Digestible Oligosaccharides Modulate the Gut Microbiota to Control the Development of Leukemia and Associated Cachexia in Mice by Bindels, Laure B, Neyrinck, Audrey M, Salazar, Nuria, Taminiau, Bernard, Druart, Céline, Muccioli, Giulio G, François, Emmanuelle, Blecker, Christophe, Richel, Aurore, Daube, Georges, Mahillon, Jacques, de los Reyes-Gavilán, Clara G, Cani, Patrice D, Delzenne, Nathalie M

“…We tested the hypothesis that changing the gut microbiota using pectic oligosaccharides (POS) or inulin (INU) differently modulates the progression of leukemia…”
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Postbiotics in the medical field under the perspective of the ISAPP definition: scientific, regulatory, and marketing considerations by Vinderola, Gabriel, Druart, Céline, Gosálbez, Luis, Salminen, Seppo, Vinot, Nina, Lebeer, Sarah

“…Diverse terms have been used in the literature to refer to the health benefits obtained from the administration of non-viable microorganisms or their cell…”
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Gut–Kidney Axis Investigations in Animal Models of Chronic Kidney Disease by Bartochowski, Piotr, Gayrard, Nathalie, Bornes, Stéphanie, Druart, Céline, Argilés, Angel, Cordaillat-Simmons, Magali, Duranton, Flore

“…Chronic kidney disease (CKD) is an incurable disease in which renal function gradually declines, resulting in no noticeable symptoms during the early stages…”
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Role of the lower and upper intestine in the production and absorption of gut microbiota-derived PUFA metabolites by Druart, Céline, Neyrinck, Audrey M, Vlaeminck, Bruno, Fievez, Veerle, Cani, Patrice D, Delzenne, Nathalie M

“…In vitro studies have suggested that isolated gut bacteria are able to metabolize PUFA into CLA (conjugated linoleic acids) and CLnA (conjugated linolenic…”
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Serum metabolite profiling yields insights into health promoting effect of A. muciniphila in human volunteers with a metabolic syndrome by Depommier, Clara, Everard, Amandine, Druart, Céline, Maiter, Dominique, Thissen, Jean-Paul, Loumaye, Audrey, Hermans, Michel P., Delzenne, Nathalie M., de Vos, Willem M., Cani, Patrice D.

“…Reduction of A. muciniphila relative abundance in the gut microbiota is a widely accepted signature associated with obesity-related metabolic disorders. Using…”
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