Search Results - "Dru, Philippe"
-
1
RAS-independent ERK activation by constitutively active KSR3 in non-chordate metazoa
Published in Nature communications (05-07-2023)“…During early development of the sea urchin embryo, activation of ERK signalling in mesodermal precursors is not triggered by extracellular RTK ligands but by a…”
Get full text
Journal Article -
2
The genome of the jellyfish Clytia hemisphaerica and the evolution of the cnidarian life-cycle
Published in Nature ecology & evolution (01-05-2019)“…Jellyfish (medusae) are a distinctive life-cycle stage of medusozoan cnidarians. They are major marine predators, with integrated neurosensory, muscular and…”
Get full text
Journal Article -
3
A wnt2 ortholog in the sea urchin Paracentrotus lividus
Published in Genesis (New York, N.Y. : 2000) (01-11-2019)“…Summary Members of the wnt gene family encode secreted glycoproteins that mediate critical intercellular communications in metazoans. Large‐scale genome and…”
Get full text
Journal Article -
4
Differential responses to Wnt and PCP disruption predict expression and developmental function of conserved and novel genes in a cnidarian
Published in PLoS genetics (01-09-2014)“…We have used Digital Gene Expression analysis to identify, without bilaterian bias, regulators of cnidarian embryonic patterning. Transcriptome comparison…”
Get full text
Journal Article -
5
Cortical anchorages and cell type segregations of maternal postplasmic/PEM RNAs in ascidians
Published in Developmental biology (01-12-2009)“…Ascidian postplasmic/PEM RNAs constitute a large class of cortical maternal RNAs which include developmental determinants (macho-1 and pem-1). We have analyzed…”
Get full text
Journal Article -
6
The aPKC-PAR-6-PAR-3 cell polarity complex localizes to the centrosome attracting body, a macroscopic cortical structure responsible for asymmetric divisions in the early ascidian embryo
Published in Journal of cell science (15-04-2006)“…Posterior blastomeres of 8-cell stage ascidian embryos undergo a series of asymmetric divisions that generate cells of unequal sizes and segregate muscle from…”
Get full text
Journal Article -
7
Maternal determinants and mRNAs in the cortex of ascidian oocytes, zygotes and embryos
Published in Biology of the cell (01-01-2005)“…The peripheral region of ascidian oocytes and zygotes contains five determinants for morphogenesis and differentiation of the embryo. The determinant for the…”
Get full text
Journal Article -
8
Polarity of the ascidian egg cortex and relocalization of cER and mRNAs in the early embryo
Published in Journal of cell science (01-06-2005)“…The mature ascidian oocyte is a large cell containing cytoplasmic and cortical domains polarized along a primary animal-vegetal (a-v) axis. The oocyte cortex…”
Get full text
Journal Article -
9
The Mediterranean mussel Mytilus galloprovincialis: a novel model for developmental studies in mollusks
Published in Development (Cambridge) (15-02-2024)“…A model organism in developmental biology is defined by its experimental amenability and by resources created for the model system by the scientific community…”
Get full text
Journal Article -
10
Identification of differentially expressed genes from multipotent epithelia at the onset of an asexual development
Published in Scientific reports (06-06-2016)“…Organisms that have evolved alternative modes of reproduction, complementary to the sexual mode, are found across metazoans. The chordate Botryllus schlosseri…”
Get full text
Journal Article -
11
From oocyte to 16‐cell stage: Cytoplasmic and cortical reorganizations that pattern the ascidian embryo
Published in Developmental dynamics (01-07-2007)“…The dorsoventral and anteroposterior axes of the ascidian embryo are defined before first cleavage by means of a series of reorganizations that reposition…”
Get full text
Journal Article -
12
A minimal molecular toolkit for mineral deposition? Biochemistry and proteomics of the test matrix of adult specimens of the sea urchin Paracentrotus lividus
Published in Journal of proteomics (16-03-2016)“…The sea urchin endoskeleton consists of a magnesium-rich biocalcite comprising a small amount of occluded organic macromolecules. This structure constitutes a…”
Get full text
Journal Article -
13
Analysis of the P. lividus sea urchin genome highlights contrasting trends of genomic and regulatory evolution in deuterostomes
Published in Cell genomics (12-04-2023)“…Sea urchins are emblematic models in developmental biology and display several characteristics that set them apart from other deuterostomes. To uncover the…”
Get full text
Journal Article -
14
Differential Responses to Wnt and PCP Disruption Predict Expression and Developmental Function of Conserved and Novel Genes in a Cnidarian: e1004590
Published in PLoS genetics (01-09-2014)“…We have used Digital Gene Expression analysis to identify, without bilaterian bias, regulators of cnidarian embryonic patterning. Transcriptome comparison…”
Get full text
Journal Article -
15
Rapidly Building Global Health Security Capacity — Uganda Demonstration Project, 2013
Published in MMWR. Morbidity and mortality weekly report (31-01-2014)“…Increasingly, the need to strengthen global capacity to prevent, detect, and respond to public health threats around the globe is being recognized. CDC, in…”
Get full text
Journal Article Newsletter -
16
Localization of domains within the Drosophila Ref(2)P protein involved in the intracellular control of sigma rhabdovirus multiplication
Published in Journal of Virology (01-07-1995)“…The ref(2)P gene of Drosophila melanogaster interferes with sigma rhabdovirus multiplication. This gene is highly variable, and the different alleles are…”
Get full text
Journal Article -
17
Unusual variability of the Drosophila melanogaster ref(2)P protein which controls the multiplication of sigma rhabdovirus
Published in Genetics (Austin) (01-04-1993)“…The ref(2)P gene of Drosophila melanogaster was identified by the discovery of two alleles, P(o) and P(p), respectively, permissive and restrictive for sigma…”
Get full text
Journal Article -
18
Immunological cross-reactions and interactions between the Drosophila melanogaster ref(2)P protein and sigma rhabdovirus proteins
Published in Journal of Virology (01-06-1993)“…The ref(2)P gene is one of the Drosophila melanogaster genes involved in the inhibition of sigma rhabdovirus multiplication. The partial restriction of viral…”
Get full text
Journal Article