Search Results - "Dropmann, Anne"

Precision-cut liver slices as an alternative method for long-term hepatotoxicity studies by Othman, Amnah, Ehnert, Sabrina, Dropmann, Anne, Ruoß, Marc, Nüssler, Andreas K., Hammad, Seddik

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TGF beta 2 fuels inflammation and fibrosis in cholestatic liver disease through macrophage and myofibroblast recruitment and activation by Albin, Jan, Meindl-Beinker, Nadja, Ebert, Matthias, Teufel, Andreas, Dooley, Steven, Dropmann, Anne

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Liver Sinusoidal Endothelial Cells Suppress Bone Morphogenetic Protein 2 Production in Response to TGFβ Pathway Activation by Colucci, Silvia, Altamura, Sandro, Marques, Oriana, Dropmann, Anne, Horvat, Natalie K., Müdder, Katja, Hammad, Seddik, Dooley, Steven, Muckenthaler, Martina U.

“…Background and Aims TGFβ/bone morphogenetic protein (BMP) signaling in the liver plays a critical role in liver disease. Growth factors, such as BMP2, BMP6,…”
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Non-canonical TGF-β signalling contributes to pro tumorigenic Smad3 linker phosphorylation in cholangiocarcinoma by Alex, Sophie, Albin, Jan, Calvisi, Diego F., Munker, Stefan, Weng, Honglei, Rahbari, Nuh N., Ebert, Matthias, Dropmann, Anne, Dooley, Steven

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Galunisertib modifies the liver fibrotic composition in the Abcb4Ko mouse model by Hammad, Seddik, Cavalcanti, Elisabetta, Werle, Julia, Caruso, Maria Lucia, Dropmann, Anne, Ignazzi, Antonia, Ebert, Matthias Philip, Dooley, Steven, Giannelli, Gianluigi

“…Transforming growth factor (TGF)-β stimulates extracellular matrix (ECM) deposition during development of liver fibrosis and cirrhosis, the most important risk…”
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TGF-β2 silencing to target biliary-derived liver diseases by Dropmann, Anne, Dooley, Steven, Dewidar, Bedair, Hammad, Seddik, Dediulia, Tatjana, Werle, Julia, Hartwig, Vanessa, Ghafoory, Shahrouz, Woelfl, Stefan, Korhonen, Hanna, Janicot, Michel, Wosikowski, Katja, Itzel, Timo, Teufel, Andreas, Schuppan, Detlef, Stojanovic, Ana, Cerwenka, Adelheid, Nittka, Stefanie, Piiper, Albrecht, Gaiser, Timo, Beraza, Naiara, Milkiewicz, Malgorzata, Milkiewicz, Piotr, Brain, John G, Jones, David E J, Weiss, Thomas S, Zanger, Ulrich M, Ebert, Matthias, Meindl-Beinker, Nadja M

“…TGF-β2 (TGF-β, transforming growth factor beta), the less-investigated sibling of TGF-β1, is deregulated in rodent and human liver diseases. Former data from…”
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Dynamic YAP expression in the non-parenchymal liver cell compartment controls heterologous cell communication by Liu, Kaijing, Wehling, Lilija, Wan, Shan, Weiler, Sofia M. E., Tóth, Marcell, Ibberson, David, Marhenke, Silke, Ali, Adnan, Lam, Macrina, Guo, Te, Pinna, Federico, Pedrini, Fabiola, Damle-Vartak, Amruta, Dropmann, Anne, Rose, Fabian, Colucci, Silvia, Cheng, Wenxiang, Bissinger, Michaela, Schmitt, Jennifer, Birner, Patrizia, Poth, Tanja, Angel, Peter, Dooley, Steven, Muckenthaler, Martina U., Longerich, Thomas, Vogel, Arndt, Heikenwälder, Mathias, Schirmacher, Peter, Breuhahn, Kai

“…Introduction The Hippo pathway and its transcriptional effectors yes-associated protein (YAP) and transcriptional coactivator with PDZ-binding motif (TAZ) are…”
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The TGF-β1 target WISP1 is highly expressed in liver cirrhosis and cirrhotic HCC microenvironment and involved in pro- and anti-tumorigenic effects by Dropmann, Anne, Alex, Sophie, Schorn, Katharina, Tong, Chenhao, Caccamo, Tiziana, Godoy, Patricio, Ilkavets, Iryna, Liebe, Roman, Gonzalez, Daniela, Hengstler, Jan G., Piiper, Albrecht, Quagliata, Luca, Matter, Matthias S., Waidmann, Oliver, Finkelmeier, Fabian, Feng, Teng, Weiss, Thomas S., Rahbari, Nuh, Birgin, Emrullah, Rasbach, Erik, Roessler, Stephanie, Breuhahn, Kai, Tóth, Marcell, Ebert, Matthias P., Dooley, Steven, Hammad, Seddik, Meindl-Beinker, Nadja M.

“…WNT1-inducible signalling pathway protein 1 (WISP1) promotes progression of several tumor entities often correlating with worse prognosis. Here its expression…”
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Digital Gastroenterology by Kusnik, Alexander, Itzel, Timo, Dooley, Steven, Dropmann, Anne, Stallkamp, Jan, Ganslandt, Thomas, Ebert, Matthias, Teufel, Andreas

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Direct Ingestion of Oxidized Red Blood Cells by Dooley, Steven, Dropmann, Anne, Hammad, Seddik, Zheng, Chaowen, Mueller, Johannes, He, Songqing, Mueller, Sebastian, Li, Siyuan, Chen, Cheng, Lyu, Huanran

“…Purpose: Both hepatic iron accumulation and hemolysis have been identified as independent prognostic factor in alcohol- related liver disease (ALD); however,…”
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Direct Ingestion of Oxidized Red Blood Cells by Hepatocytes by Zheng, Chaowen, Li, Siyuan, Lyu, Huanran, Chen, Cheng, Mueller, Johannes, Dropmann, Anne, Hammad, Seddik, Dooley, Steven, He, Songqing, Mueller, Sebastian

“…Purpose: Both hepatic iron accumulation and hemolysis have been identified as independent prognostic factor in alcohol- related liver disease (ALD); however,…”
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TGF-β1 and TGF-β2 abundance in liver diseases of mice and men by Dropmann, Anne, Dediulia, Tatjana, Breitkopf-Heinlein, Katja, Korhonen, Hanna, Janicot, Michel, Weber, Susanne N, Thomas, Maria, Piiper, Albrecht, Bertran, Esther, Fabregat, Isabel, Abshagen, Kerstin, Hess, Jochen, Angel, Peter, Coulouarn, Cédric, Dooley, Steven, Meindl-Beinker, Nadja M

“…TGF-β1 is a major player in chronic liver diseases promoting fibrogenesis and tumorigenesis through various mechanisms. The expression and function of TGF-β2…”
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Human skin-derived ABCB5+ stem cell injection improves liver disease parameters in Mdr2KO mice by Hartwig, Vanessa, Dewidar, Bedair, Lin, Tao, Dropmann, Anne, Ganss, Christoph, Kluth, Mark Andreas, Tappenbeck, Nils, Tietze, Lysann, Christ, Bruno, Frank, Markus, Vogelmann, Roger, Ebert, Matthias Philip Alexander, Dooley, Steven

“…Although liver transplantation is a potential effective cure for patients with end-stage liver diseases, this strategy has several drawbacks including high…”
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Tumour-specific activation of a tumour-blood transport improves the diagnostic accuracy of blood tumour markers in mice by Schmithals, Christian, Kakoschky, Bianca, Denk, Dominic, von Harten, Maike, Klug, Jan Henrik, Hintermann, Edith, Dropmann, Anne, Hamza, Eman, Jacomin, Anne Claire, Marquardt, Jens U., Zeuzem, Stefan, Schirmacher, Peter, Herrmann, Eva, Christen, Urs, Vogl, Thomas J., Waidmann, Oliver, Dooley, Steven, Finkelmeier, Fabian, Piiper, Albrecht

“…The accuracy of blood-based early tumour recognition is compromised by signal production at non-tumoral sites, low amount of signal produced by small tumours,…”
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Correction to: Human skin-derived ABCB5+ stem cell injection improves liver disease parameters in Mdr2KO mice by Hartwig, Vanessa, Dewidar, Bedair, Lin, Tao, Dropmann, Anne, Ganss, Christoph, Kluth, Mark Andreas, Tappenbeck, Nils, Tietze, Lysann, Christ, Bruno, Frank, Markus Hermann, Vogelmann, Roger, Ebert, Matthias Philip Alexander, Dooley, Steven

“…We wish to submit a corrigendum to the above-mentioned article. Thank you very much for consideration and publication…”
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Direct Ingestion of Oxidized Red Blood Cells (Efferocytosis) by Hepatocytes by Zheng, Chaowen, Li, Siyuan, Lyu, Huanran, Chen, Cheng, Mueller, Johannes, Dropmann, Anne, Hammad, Seddik, Dooley, Steven, He, Songqing, Mueller, Sebastian

“…Both hepatic iron accumulation and hemolysis have been identified as independent prognostic factor in alcohol-related liver disease (ALD); however, the…”
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The Interplay of TGF-β1 and Cholesterol Orchestrating Hepatocyte Cell Fate, EMT, and Signals for HSC ActivationSummary by Sai Wang, Frederik Link, Mei Han, Roohi Chaudhary, Anastasia Asimakopoulos, Roman Liebe, Ye Yao, Seddik Hammad, Anne Dropmann, Marinela Krizanac, Claudia Rubie, Laura Kim Feiner, Matthias Glanemann, Matthias P.A. Ebert, Ralf Weiskirchen, Yoav I. Henis, Marcelo Ehrlich, Steven Dooley

“…Background & Aims: Transforming growth factor-β1 (TGF-β1) plays important roles in chronic liver diseases, including metabolic dysfunction–associated steatotic…”
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The Interplay of TGF-β1 and Cholesterol Orchestrating Hepatocyte Cell Fate, EMT, and Signals for HSC Activation by Wang, Sai, Link, Frederik, Han, Mei, Chaudhary, Roohi, Asimakopoulos, Anastasia, Liebe, Roman, Yao, Ye, Hammad, Seddik, Dropmann, Anne, Krizanac, Marinela, Rubie, Claudia, Feiner, Laura Kim, Glanemann, Matthias, Ebert, Matthias P.A., Weiskirchen, Ralf, Henis, Yoav I., Ehrlich, Marcelo, Dooley, Steven

“…Transforming growth factor-β1 (TGF-β1) plays important roles in chronic liver diseases, including metabolic dysfunction–associated steatotic liver disease…”
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Tumour-specific activation of a tumour-blood transport improves the diagnostic accuracy of blood tumour markers in miceResearch in context by Christian Schmithals, Bianca Kakoschky, Dominic Denk, Maike von Harten, Jan Henrik Klug, Edith Hintermann, Anne Dropmann, Eman Hamza, Anne Claire Jacomin, Jens U. Marquardt, Stefan Zeuzem, Peter Schirmacher, Eva Herrmann, Urs Christen, Thomas J. Vogl, Oliver Waidmann, Steven Dooley, Fabian Finkelmeier, Albrecht Piiper

“…Background: The accuracy of blood-based early tumour recognition is compromised by signal production at non-tumoral sites, low amount of signal produced by…”
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