Search Results - "Droege, Molly E."
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Admission thrombelastography does not guide dose adjustment of enoxaparin in trauma patients
Published in Surgery open science (01-10-2020)“…Enoxaparin is used as chemoprophylaxis to reduce incidence of venous thromboembolism and its complications following trauma. Serum anti-Xa monitoring is used…”
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2
Efficacy and Safety of Anti-Xa Guided versus Fixed Dosing of Low Molecular Weight Heparin for Prevention of Venous Thromboembolism in Trauma Patients – A Systematic Review and Meta-Analysis
Published in Annals of surgery (01-05-2023)“…Trauma patients are at high risk of venous thromboembolism (VTE). We summarize the comparative efficacy and safety of anti-Xa-guided versus fixed dosing for…”
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Pharmacokinetics of Levetiracetam Seizure Prophylaxis in Severe Traumatic Brain Injury
Published in The Annals of pharmacotherapy (01-07-2024)“…Background: Drug pharmacokinetics (PK) are altered in neurocritically ill patients, and optimal levetiracetam dosing for seizure prophylaxis is unknown…”
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Cefepime Population Pharmacokinetics and Target Attainment in Critically Ill Patients on Continuous Renal Replacement Therapy
Published in Antimicrobial agents and chemotherapy (18-05-2021)“…Sepsis causes half of acute kidney injuries in the intensive care unit (ICU). ICU patients may need continuous renal replacement therapy (CRRT), which will…”
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Applying Cefepime Population Pharmacokinetics to Critically Ill Patients Receiving Continuous Renal Replacement Therapy
Published in Antimicrobial agents and chemotherapy (18-01-2022)“…Patients admitted to the intensive care unit (ICU) may need continuous renal replacement therapy (CRRT) due to acute kidney injury or worsening of underlying…”
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Intercostal liposomal bupivacaine injection for rib fractures: A prospective randomized controlled trial
Published in The journal of trauma and acute care surgery (01-02-2022)“…Blunt chest wall injury accounts for 15% of trauma admissions. Previous studies have shown that the number of rib fractures predicts inpatient opioid…”
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Impact of a Multimodal Analgesia Protocol on Inpatient and Outpatient Opioid Use in Acute Trauma
Published in The Journal of surgical research (01-12-2021)“…Multimodal analgesia protocols have been implemented after elective surgery to reduce opioid use, however there is limited data on utility after polytrauma…”
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Pharmacokinetics and Pharmacodynamics of Extended‐Infusion Cefepime in Critically Ill Patients Receiving Continuous Renal Replacement Therapy: A Prospective, Open‐Label Study
Published in Pharmacotherapy (01-11-2019)“…Study Objective To evaluate extended‐infusion (EI) cefepime pharmacokinetics (PK) and pharmacodynamic target attainment in critically ill patients receiving…”
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Clinical Experience, Characteristics, and Performance of an Acetaminophen Absorption Test in Critically Ill Patients
Published in American journal of therapeutics (01-03-2023)“…Altered drug and nutrient absorption presents a unique challenge in critically ill patients. Performing an acetaminophen absorption test (AAT) has been used as…”
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Retrospective Evaluation of Venous Thromboembolism Prophylaxis in Elderly, High-Risk Trauma Patients
Published in The Journal of surgical research (01-05-2020)“…Venous thromboembolism (VTE) risk increases with age. Scarce data exist for patients age ≥65 y. This study evaluated VTE incidence in elderly, high-risk trauma…”
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Ketamine versus hydromorphone patient-controlled analgesia for acute pain in trauma patients
Published in The Journal of surgical research (01-05-2018)“…It is unknown whether ketamine administered via patient-controlled analgesia (PCA) provides adequate analgesia while reducing opioid consumption in the…”
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Effect of a dalteparin prophylaxis protocol using anti-factor Xa concentrations on venous thromboembolism in high-risk trauma patients
Published in The journal of trauma and acute care surgery (01-02-2014)“…Low anti-factor Xa (anti-Xa) concentrations with twice-daily enoxaparin are associated with venous thromboembolism (VTE) in high-risk trauma patients. Concerns…”
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13
Application of Antibiotic Pharmacodynamics and Dosing Principles in Patients With Sepsis
Published in Critical care nurse (01-04-2016)“…Sepsis is associated with marked mortality, which may be reduced by prompt initiation of adequate, appropriate doses of antibiotic. Critically ill patients…”
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Major publications in the critical care pharmacotherapy literature: January–December 2014
Published in American journal of health-system pharmacy (15-11-2015)“…PURPOSENine recently published articles and one guideline with important implications for critical care pharmacy practice are summarized. SUMMARYThe Critical…”
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15
Intercostal Liposomal Bupivacaine Injection For Rib Fractures; A Prospective Randomized Controlled Trial
Published in The journal of trauma and acute care surgery (15-11-2021)Get full text
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16
Octreotide Dosing in the Medical Management of Chyle Leak Following Otolaryngologic, Thoracic, and Trauma Surgery: A 9-Year Evaluation
Published in Journal of pharmacy practice (01-02-2024)“…Background: Chyle leak is a rare complication following otolaryngologic, thoracic, and trauma surgery wherein the thoracic duct is transected. Case reports and…”
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Clinical Experience, Characteristics, and Performance of an Acetaminophen Absorption Test in Critically Ill Patients
Published in American journal of therapeutics (10-08-2021)Get full text
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