Search Results - "Drobniewski, Francis A."

Whole-genome sequencing for prediction of Mycobacterium tuberculosis drug susceptibility and resistance: a retrospective cohort study by Walker, Timothy M, Dr, Kohl, Thomas A, PhD, Omar, Shaheed V, MSc, Hedge, Jessica, PhD, Del Ojo Elias, Carlos, MSc, Bradley, Phelim, MPhil, Iqbal, Zamin, DPhil, Feuerriegel, Silke, PhD, Niehaus, Katherine E, MS, Wilson, Daniel J, DPhil, Clifton, David A, DPhil, Kapatai, Georgia, PhD, Ip, Camilla L C, PhD, Bowden, Rory, PhD, Drobniewski, Francis A, PhD, Allix-Béguec, Caroline, PhD, Gaudin, Cyril, PhD, Parkhill, Julian, PhD, Diel, Roland, PhD, Supply, Philip, PhD, Crook, Derrick W, FRCPath, Smith, E Grace, FRCPath, Walker, A Sarah, PhD, Ismail, Nazir, FCPath, Niemann, Stefan, PhD, Peto, Tim E A, FRCP

“…Summary Background Diagnosing drug-resistance remains an obstacle to the elimination of tuberculosis. Phenotypic drug-susceptibility testing is slow and…”
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High-dose vitamin D3 during intensive-phase antimicrobial treatment of pulmonary tuberculosis: a double-blind randomised controlled trial by Martineau, Adrian R, Dr, Timms, Peter M, FRCPath, Bothamley, Graham H, FRCP, Hanifa, Yasmeen, MRCGP, Islam, Kamrul, BSc, Claxton, Alleyna P, FRCPath, Packe, Geoffrey E, FRCP, Moore-Gillon, John C, FRCP, Darmalingam, Mathina, FCPSA, Davidson, Robert N, MD, Milburn, Heather J, FRCP, Baker, Lucy V, FRCP, Barker, Richard D, MD, Woodward, Nicholas J, FRCR, Venton, Timothy R, FIBMS, Barnes, Korina E, FIBMS, Mullett, Christopher J, BSc, Coussens, Anna K, PhD, Rutterford, Clare M, MSc, Mein, Charles A, DPhil, Davies, Geraint R, MRCP, Wilkinson, Robert J, Prof, Nikolayevskyy, Vladyslav, PhD, Drobniewski, Francis A, Prof, Eldridge, Sandra M, Prof, Griffiths, Christopher J, Prof

“…Summary Background Vitamin D was used to treat tuberculosis in the pre-antibiotic era, and its metabolites induce antimycobacterial immunity in vitro. Clinical…”
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Vitamin D accelerates resolution of inflammatory responses during tuberculosis treatment by Coussens, Anna K., Wilkinson, Robert J., Hanifa, Yasmeen, Nikolayevskyy, Vladyslav, Elkington, Paul T., Islam, Kamrul, Timms, Peter M., Venton, Timothy R., Bothamley, Graham H., Packe, Geoffrey E., Darmalingam, Mathina, Davidson, Robert N., Milburn, Heather J., Baker, Lucy V., Barker, Richard D., Mein, Charles A., Bhaw-Rosun, Leena, Nuamah, Rosamond, Young, Douglas B., Drobniewski, Francis A., Griffiths, Christopher J., Martineau, Adrian R.

“…Calcidiol, the major circulating metabolite of vitamin D, supports induction of pleiotropic antimicrobial responses in vitro. Vitamin D supplementation…”
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Ethnic variation in inflammatory profile in tuberculosis by Coussens, Anna K, Wilkinson, Robert J, Nikolayevskyy, Vladyslav, Elkington, Paul T, Hanifa, Yasmeen, Islam, Kamrul, Timms, Peter M, Bothamley, Graham H, Claxton, Alleyna P, Packe, Geoffrey E, Darmalingam, Mathina, Davidson, Robert N, Milburn, Heather J, Baker, Lucy V, Barker, Richard D, Drobniewski, Francis A, Mein, Charles A, Bhaw-Rosun, Leena, Nuamah, Rosamond A, Griffiths, Christopher J, Martineau, Adrian R

“…Distinct phylogenetic lineages of Mycobacterium tuberculosis (MTB) cause disease in patients of particular genetic ancestry, and elicit different patterns of…”
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Evaluation of MGIT 960-Based Antimicrobial Testing and Determination of Critical Concentrations of First- and Second-Line Antimicrobial Drugs with Drug-Resistant Clinical Strains of Mycobacterium tuberculosis by Krüüner, Annika, Yates, Malcolm D, Drobniewski, Francis A

“…The objectives of this study were to (i) compare agreement of the MGIT 960 system for first-line drugs with a methodology (the resistance ratio method [RRM])…”
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Survival of civilian and prisoner drug-sensitive, multi- and extensive drug- resistant tuberculosis cohorts prospectively followed in Russia by Balabanova, Yanina, Nikolayevskyy, Vladyslav, Ignatyeva, Olga, Kontsevaya, Irina, Rutterford, Clare M, Shakhmistova, Anastasiya, Malomanova, Nadezhda, Chinkova, Yulia, Mironova, Svetlana, Fedorin, Ivan, Drobniewski, Francis A

“…A long-term observational study was conducted in Samara, Russia to assess the survival and risk factors for death of a cohort of non-multidrug resistant…”
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Prediction of Susceptibility to First-Line Tuberculosis Drugs by DNA Sequencing by Allix-Béguec, Caroline, Arandjelovic, Irena, Bi, Lijun, Beckert, Patrick, Bonnet, Maryline, Bradley, Phelim, Cabibbe, Andrea M, Cancino-Muñoz, Irving, Caulfield, Mark J, Chaiprasert, Angkana, Cirillo, Daniela M, Clifton, David A, Comas, Iñaki, Crook, Derrick W, De Filippo, Maria R, de Neeling, Han, Diel, Roland, Drobniewski, Francis A, Faksri, Kiatichai, Farhat, Maha R, Fleming, Joy, Fowler, Philip, Fowler, Tom A, Gao, Qian, Gardy, Jennifer, Gascoyne-Binzi, Deborah, Gibertoni-Cruz, Ana-Luiza, Gil-Brusola, Ana, Golubchik, Tanya, Gonzalo, Ximena, Grandjean, Louis, He, Guangxue, Guthrie, Jennifer L, Hoosdally, Sarah, Hunt, Martin, Iqbal, Zamin, Ismail, Nazir, Johnston, James, Khanzada, Faisal M, Khor, Chiea C, Kohl, Thomas A, Kong, Clare, Lipworth, Sam, Liu, Qingyun, Maphalala, Gugu, Martinez, Elena, Mathys, Vanessa, Merker, Matthias, Miotto, Paolo, Mistry, Nerges, Moore, David A J, Murray, Megan, Niemann, Stefan, Omar, Shaheed V, Ong, Rick T-H, Peto, Tim E A, Posey, James E, Prammananan, Therdsak, Pym, Alexander, Rodrigues, Camilla, Rodrigues, Mabel, Rodwell, Timothy, Rossolini, Gian M, Sánchez Padilla, Elisabeth, Schito, Marco, Shen, Xin, Shendure, Jay, Sintchenko, Vitali, Sloutsky, Alex, Smith, E Grace, Snyder, Matthew, Soetaert, Karine, Starks, Angela M, Supply, Philip, Suriyapol, Prapat, Tahseen, Sabira, Tang, Patrick, Teo, Yik-Ying, Thuong, Thuong N T, Thwaites, Guy, Tortoli, Enrico, van Soolingen, Dick, Walker, A Sarah, Walker, Timothy M, Wilcox, Mark, Wilson, Daniel J, Wyllie, David, Yang, Yang, Zhang, Hongtai, Zhao, Yanlin, Zhu, Baoli

“…Proper treatment of tuberculosis requires a combination of drugs to which the causative organism is susceptible. In this report, genotypic assessment of…”
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Molecular Epidemiology of Disease Due to Mycobacterium bovis in Humans in the United Kingdom by GIBSON, Andrea L, HEWINSON, Glyn, GOODCHILD, Tony, WATT, Brian, STORY, Alistair, INWALD, Jacqueline, DROBNIEWSKI, Francis A

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High-dose vitamin D 3 during intensive-phase antimicrobial treatment of pulmonary tuberculosis: a double-blind randomised controlled trial by Martineau, Adrian R, Timms, Peter M, Bothamley, Graham H, Hanifa, Yasmeen, Islam, Kamrul, Claxton, Alleyna P, Packe, Geoffrey E, Moore-Gillon, John C, Darmalingam, Mathina, Davidson, Robert N, Milburn, Heather J, Baker, Lucy V, Barker, Richard D, Woodward, Nicholas J, Venton, Timothy R, Barnes, Korina E, Mullett, Christopher J, Coussens, Anna K, Rutterford, Clare M, Mein, Charles A, Davies, Geraint R, Wilkinson, Robert J, Nikolayevskyy, Vladyslav, Drobniewski, Francis A, Eldridge, Sandra M, Griffiths, Christopher J

“…Vitamin D was used to treat tuberculosis in the pre-antibiotic era, and its metabolites induce antimycobacterial immunity in vitro. Clinical trials…”
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Progression Toward an Improved DNA Amplification-Based Typing Technique in the Study of Mycobacterium tuberculosis Epidemiology by Gopaul, Krishna K, Brown, Timothy J, Gibson, Andrea L, Yates, Malcolm D, Drobniewski, Francis A

“…While high-copy-number IS6110-based restriction fragment length polymorphism (HCN-RFLP) is the gold standard for typing most Mycobacterium tuberculosis…”
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DNA Fingerprint Changes in Tuberculosis: Reinfection, Evolution, or Laboratory Error? by Glynn, Judith R., Crampin, Amelia C., Ngwira, Bagrey M., Mwaungulu, Frank D., Black, Gillian F., Chaguluka, Steven D., Mwafulirwa, Donex T., Floyd, Sian, Murphy, Caroline, Drobniewski, Francis A., Fine, Paul E. M.

“…Background. DNA fingerprint patterns of Mycobacterium tuberculosis strains vary within individuals and between epidemiologically linked individuals because of…”
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Mycobacterium tuberculosis Beijing genotype, northern Malawi by Glynn, Judith R, Crampin, Amelia C, Traore, Hamidou, Yates, Malcolm D, Mwaungulu, Frank D, Ngwira, Bagrey M, Chaguluka, Steven D, Mwafulirwa, Donex T, Floyd, Sian, Murphy, Caroline, Drobniewski, Francis A, Fine, Paul E M

“…In a 7-year population-based study in Malawi, we showed that Beijing genotype tuberculosis (TB) increased as a proportion of TB cases. All the Beijing genotype…”
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Resistance profile and risk factors of drug resistant tuberculosis in the Baltic countries by Ignatyeva, Olga, Balabanova, Yanina, Nikolayevskyy, Vladyslav, Koshkarova, Ekaterina, Radiulyte, Birute, Davidaviciene, Edita, Riekstina, Vija, Jaama, Kadri, Danilovits, Manfred, Popa, Cristina M, Drobniewski, Francis A

“…Summary The rates of multi- and extensively drug-resistant tuberculosis (X/MDRTB) in the Baltic countries are the highest within the European Union hampering…”
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Evaluation of a Rapid PCR-Based Epidemiological Typing Method for Routine Studies of Mycobacterium tuberculosis by YATES, Malcolm D, DROBNIEWSKI, Francis A, WILSON, Stuart M

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Risk factors for drug-resistant tuberculosis patients in Lithuania, 2002-2008 by Balabanova, Yanina, Radiulyte, Birute, Davidaviciene, Edita, Hooper, Richard, Ignatyeva, Olga, Nikolayevskyy, Vladyslav, Drobniewski, Francis A

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Survival of drug resistant tuberculosis patients in Lithuania: retrospective national cohort study by Balabanova, Yanina, Radiulyte, Birute, Davidaviciene, Edita, Hooper, Richard, Ignatyeva, Olga, Nikolayevskyy, Vladyslav, Drobniewski, Francis A

“…ObjectiveTo establish risk factors influencing survival of patients with multidrug-resistant and extensively drug-resistant tuberculosis (MDR/XDRTB).DesignAll…”
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Comparison of Three Molecular Assays for Rapid Detection of Rifampin Resistance in Mycobacterium tuberculosis by WATTERSON, S. A, WILSON, S. M, YATES, M. D, DROBNIEWSKI, F. A

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Non-pulmonary tuberculosis and mycobacterial infection by Drobniewski, Francis A, Amin, Amit K, Balabanova, Yanina

“…Abstract Tuberculosis (TB) can affect any part of the body, and non-pulmonary TB accounted for 43% of notifications in England and Wales in 2007…”
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Diagnosis of tuberculosis and drug resistance: what can new tools bring us? [State of the art series. New tools. Number 1 in the series] by Drobniewski, F., Nikolayevskyy, V., Balabanova, Y., Bang, D., Papaventsis, D.

“…This is an exciting time for tuberculosis (TB) diagnostics. The technology for rapid diagnosis of TB and rifampicin (RMP) resistance in pulmonary sputum…”
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Specificity of IS6110-Based DNA Fingerprinting and Diagnostic Techniques for Mycobacterium tuberculosis Complex by GITHUI, W. A, WILSON, S. M, DROBNIEWSKII, F. A

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