Search Results - "Driver, Kristy E."

Telomere length in prospective and retrospective cancer case-control studies by Pooley, Karen A, Sandhu, Manjinder S, Tyrer, Jonathan, Shah, Mitul, Driver, Kristy E, Luben, Robert N, Bingham, Sheila A, Ponder, Bruce A J, Pharoah, Paul D P, Khaw, Kay-Tee, Easton, Douglas F, Dunning, Alison M

“…Previous studies have reported that shorter mean telomere length in lymphocytes was associated with increased susceptibility to common diseases of aging, and…”
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Common Polymorphisms in the Prostaglandin Pathway Genes and Their Association with Breast Cancer Susceptibility and Survival by ABRAHAM, Jean E, HARRINGTON, Patricia, DRIVER, Kristy E, TYRER, Jonathan, EASTON, Douglas F, DUNNING, Alison M, PHAROAH, Paul D. P

“…Purpose: There is evidence that genetic variation in the prostaglandin pathway affects cancer susceptibility and progression. Conflicting data from several…”
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Common Single-Nucleotide Polymorphisms in DNA Double-Strand Break Repair Genes and Breast Cancer Risk by Pooley, Karen A, Baynes, Caroline, Driver, Kristy E, Tyrer, Jonathan, Azzato, Elizabeth M, Pharoah, Paul D P, Easton, Douglas F, Ponder, Bruce A J, Dunning, Alison M

“…The proteins involved in homologous recombination are instrumental in the error-free repair of dsDNA breakages, and common germ-line variations in these genes…”
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Subtyping of breast cancer by immunohistochemistry to investigate a relationship between subtype and short and long term survival: a collaborative analysis of data for 10,159 cases from 12 studies by Blows, Fiona M, Driver, Kristy E, Schmidt, Marjanka K, Broeks, Annegien, van Leeuwen, Flora E, Wesseling, Jelle, Cheang, Maggie C, Gelmon, Karen, Nielsen, Torsten O, Blomqvist, Carl, Heikkilä, Päivi, Heikkinen, Tuomas, Nevanlinna, Heli, Akslen, Lars A, Bégin, Louis R, Foulkes, William D, Couch, Fergus J, Wang, Xianshu, Cafourek, Vicky, Olson, Janet E, Baglietto, Laura, Giles, Graham G, Severi, Gianluca, McLean, Catriona A, Southey, Melissa C, Rakha, Emad, Green, Andrew R, Ellis, Ian O, Sherman, Mark E, Lissowska, Jolanta, Anderson, William F, Cox, Angela, Cross, Simon S, Reed, Malcolm W R, Provenzano, Elena, Dawson, Sarah-Jane, Dunning, Alison M, Humphreys, Manjeet, Easton, Douglas F, García-Closas, Montserrat, Caldas, Carlos, Pharoah, Paul D, Huntsman, David

“…Immunohistochemical markers are often used to classify breast cancer into subtypes that are biologically distinct and behave differently. The aim of this study…”
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Multiple Loci With Different Cancer Specificities Within the 8q24 Gene Desert by Ghoussaini, Maya, Song, Honglin, Koessler, Thibaud, Al Olama, Ali Amin, Kote-Jarai, Zsofia, Driver, Kristy E., Pooley, Karen A., Ramus, Susan J., Kjaer, Susanne Krüger, Hogdall, Estrid, DiCioccio, Richard A., Whittemore, Alice S., Gayther, Simon A., Giles, Graham G., Guy, Michelle, Edwards, Stephen M., Morrison, Jonathan, Donovan, Jenny L., Hamdy, Freddie C., Dearnaley, David P., Ardern-Jones, Audrey T., Hall, Amanda L., O'Brien, Lynne T., Gehr-Swain, Beatrice N., Wilkinson, Rosemary A., Brown, Paul M., Hopper, John L., Neal, David E., Pharoah, Paul D. P., Ponder, Bruce A. J., Eeles, Rosalind A., Easton, Douglas F., Dunning, Alison M.

“…Recent studies based on genome-wide association, linkage, and admixture scan analysis have reported associations of various genetic variants in 8q24 with…”
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CYP2D6 gene variants: association with breast cancer specific survival in a cohort of breast cancer patients from the United Kingdom treated with adjuvant tamoxifen by Abraham, Jean E, Maranian, Mel J, Driver, Kristy E, Platte, Radka, Kalmyrzaev, Bolot, Baynes, Caroline, Luccarini, Craig, Shah, Mitul, Ingle, Susan, Greenberg, David, Earl, Helena M, Dunning, Alison M, Pharoah, Paul D P, Caldas, Carlos

“…Tamoxifen is one of the most effective adjuvant breast cancer therapies available. Its metabolism involves the phase I enzyme, cytochrome P4502D6 (CYP2D6),…”
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No Association between TERT CLPTM1L Single Nucleotide Polymorphism rs401681 and Mean Telomere Length or Cancer Risk by POOLEY, Karen A, TYRER, Jonathan, EASTON, Douglas F, DUNNING, Alison M, SHAH, Mitul, DRIVER, Kristy E, LEYLAND, Jean, BROWN, Judith, AUDLEY, Tina, MCGUFFOG, Lesley, PONDER, Bruce A. J, PHAROAH, Paul D. P

“…A recent study reported genetic variants in the TERT-CLPTM1L locus that were associated with mean telomere length, and with risk of multiple cancers. We…”
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Familial relative risks for breast cancer by pathological subtype: a population-based cohort study by Mavaddat, Nasim, Pharoah, Paul D, Blows, Fiona, Driver, Kristy E, Provenzano, Elena, Thompson, Deborah, Macinnis, Robert J, Shah, Mitul, Easton, Douglas F, Antoniou, Antonis C

“…The risk of breast cancer to first degree relatives of breast cancer patients is approximately twice that of the general population. Breast cancer, however, is…”
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Association of single-nucleotide polymorphisms in the cell cycle genes with breast cancer in the British population by Driver, Kristy E., Song, Honglin, Lesueur, Fabienne, Ahmed, Shahana, Barbosa-Morais, Nuno L., Tyrer, Jonathan P., Ponder, Bruce A.J., Easton, Douglas F., Pharoah, Paul D.P., Dunning, Alison M.

“…Using a large-scale case–control study, we examined whether common single-nucleotide polymorphisms (SNPs) within 13 genes involved in the cell cycle pathway…”
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CYP2D6 Gene Variants and Their Association with Breast Cancer Susceptibility by ABRAHAM, Jean E, MARANIAN, Mel J, CALDAS, Carlos, DRIVER, Kristy E, PLATTE, Radka, KALMYRZAEV, Bolot, BAYNES, Caroline, LUCCARINI, Craig, EARL, Helena M, DUNNING, Alison M, PHAROAH, Paul D. P

“…The gene encoding the phase I enzyme cytochrome P4502D6 (CYP2D6) has been previously investigated for its potential predictive role in the efficacy of breast…”
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Effects of common germline genetic variation in cell cycle control genes on breast cancer survival: results from a population-based cohort by Azzato, Elizabeth M, Driver, Kristy E, Lesueur, Fabienne, Shah, Mitul, Greenberg, David, Easton, Douglas F, Teschendorff, Andrew E, Caldas, Carlos, Caporaso, Neil E, Pharoah, Paul D P

“…Somatic alterations have been shown to correlate with breast cancer prognosis and survival, but less is known about the effects of common inherited genetic…”
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No association between TERT-CLPTM1L SNP rs401681 and mean telomere length or cancer risk by Pooley, Karen A., Tyrer, Jonathan, Shah, Mitul, Driver, Kristy E., Leyland, Jean, Brown, Judith, Audley, Tina, McGuffog, Lesley, Ponder, Bruce A.J., Pharoah, Paul D.P., Easton, Douglas F., Dunning, Alison M.

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Subtyping of Breast Cancer by Immunohistochemistry to Investigate a Relationship between Subtype and Short and Long Term Survival: A Collaborative Analysis of Data for 10,159 Cases from 12 Studies: e1000279 by Blows, Fiona M, Driver, Kristy E, Schmidt, Marjanka K, Broeks, Annegien, Leeuwen, Flora Evan, Wesseling, Jelle, Cheang, Maggie C, Gelmon, Karen, Nielsen, Torsten O, Blomqvist, Carl, Heikkilä, Päivi, Heikkinen, Tuomas, Nevanlinna, Heli, Akslen, Lars A, Bégin, Louis R, Foulkes, William D, Couch, Fergus J, Wang, Xianshu, Cafourek, Vicky, Olson, Janet E, Baglietto, Laura, Giles, Graham G, Severi, Gianluca, McLean, Catriona A, Southey, Melissa C, Rakha, Emad, Green, Andrew R, Ellis, Ian O, Sherman, Mark E, Lissowska, Jolanta, Anderson, William F, Cox, Angela, Cross, Simon S, Reed, Malcolm WR, Provenzano, Elena, Dawson, Sarah-Jane, Dunning, Alison M, Humphreys, Manjeet, Easton, Douglas F, García-Closas, Montserrat, Caldas, Carlos, Pharoah, Paul D, Huntsman, David

“…Background Immunohistochemical markers are often used to classify breast cancer into subtypes that are biologically distinct and behave differently. The aim of…”
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