Search Results - "Driscoll, Timothy A."

Unrelated donor umbilical cord blood transplantation for inherited metabolic disorders in 159 pediatric patients from a single center: influence of cellular composition of the graft on transplantation outcomes by Prasad, Vinod K., Mendizabal, Adam, Parikh, Suhag H., Szabolcs, Paul, Driscoll, Timothy A., Page, Kristin, Lakshminarayanan, Sonali, Allison, June, Wood, Susan, Semmel, Deborah, Escolar, Maria L., Martin, Paul L., Carter, Shelly, Kurtzberg, Joanne

“…Outcomes of 159 young patients with inherited metabolic disorders (IMDs) undergoing transplantation with partially HLA-mismatched unrelated donor umbilical…”
Get full text

Comparison of Pharmacokinetics and Safety of Voriconazole Intravenous-to-Oral Switch in Immunocompromised Children and Healthy Adults by DRISCOLL, Timothy A, YU, Lolie C, PING LIU, FRANGOUL, Haydar, KRANCE, Robert A, NEMECEK, Eneida, BLUMER, Jeffrey, ARRIETA, Antonio, GRAHAM, Michael L, BRADFIELD, Scott M, BARUCH, Alice

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

Pooled safety analysis of tisagenlecleucel in children and young adults with B cell acute lymphoblastic leukemia by Levine, John E, Grupp, Stephan A, Pulsipher, Michael A, Dietz, Andrew C, Rives, Susana, Myers, G Douglas, August, Keith J, Verneris, Michael R, Buechner, Jochen, Laetsch, Theodore W, Bittencourt, Henrique, Baruchel, Andre, Boyer, Michael W, De Moerloose, Barbara, Qayed, Muna, Davies, Stella M, Phillips, Christine L, Driscoll, Timothy A, Bader, Peter, Schlis, Krysta, Wood, Patricia A, Mody, Rajen, Yi, Lan, Leung, Mimi, Eldjerou, Lamis K, June, Carl H, Maude, Shannon L

“…BackgroundTisagenlecleucel, an anti-CD19 chimeric antigen receptor T cell therapy, has demonstrated efficacy in children and young adults with…”
Get full text

Comparison of Pharmacokinetics and Safety of Voriconazole Intravenous-to-Oral Switch in Immunocompromised Adolescents and Healthy Adults by DRISCOLL, Timothy A, FRANGOUL, Haydar, NEMECEK, Eneida R, MURPHEY, Donald K, YU, Lolie C, BLUMER, Jeffrey, KRANCE, Robert A, BARUCH, Alice, PING LIU

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

Correction of chronic granulomatous disease after second unrelated-donor umbilical cord blood transplantation by Parikh, Suhag H., Szabolcs, Paul, Prasad, Vinod K., Lakshminarayanan, Sonali, Martin, Paul L., Driscoll, Timothy A., Kurtzberg, Joanne

“…Allogeneic hematopoietic stem cell transplantation (HSCT) is curative for chronic granulomatous disease (CGD), but many patients lack a suitably matched…”
Get full text

Reduction in Mortality after Umbilical Cord Blood Transplantation in Children Over a 20-Year Period (1995-2014) by Spees, Lisa P., Martin, Paul L., Kurtzberg, Joanne, Stokhuyzen, Andre, McGill, Lauren, Prasad, Vinod K., Driscoll, Timothy A., Parikh, Suhag H., Page, Kristin M., Vinesett, Richard, Severyn, Christopher, Sung, Anthony D., Proia, Alan D., Jenkins, Kirsten, Arshad, Mehreen, Steinbach, William J., Seed, Patrick C., Kelly, Matthew S.

“…•Survival among children after UCBT has improved substantially over the past 20years.•Nearly half of the improved survival was related to a decline in…”
Get full text

Ruxolitinib for the treatment of steroid refractory pediatric chronic graft‐versus‐host disease by Belina, Morgan E., Driscoll, Timothy A., Blanchard, Sarah K., Cardones, Adela R.

“…Chronic graft‐versus‐host disease (cGVHD) of the skin is a serious cause of long‐term morbidity and mortality among patients who receive hematopoietic stem…”
Get full text

Value of surgical resection in children with high-risk neuroblastoma by Englum, Brian R., Rialon, Kristy L., Speicher, Paul J., Gulack, Brian, Driscoll, Timothy A., Kreissman, Susan G., Rice, Henry E.

“…Background The value of gross total resection (GTR) for children with high‐risk neuroblastoma (NB) is controversial. We hypothesized that patients undergoing…”
Get full text

No impact of CD34+ cell dose on outcome among children undergoing autologous hematopoietic stem cell transplant for high-risk neuroblastoma by Knight, Tristan E., Ahn, Kwang Woo, Hebert, Kyle M., Atshan, Rasha, Wall, Donna A., Chiengthong, Kanhatai, Lund, Troy C., Prestidge, Tim, Rangarajan, Hemalatha G., Dvorak, Christopher C., Auletta, Jeffery J., Kent, Michael, Hashem, Hasan, Talano, Julie-An, Rotz, Seth J., Fraint, Ellen, Myers, Kasiani C., Leung, Wing, Sharma, Akshay, Bhatt, Neel S., Driscoll, Timothy A., Yu, Lolie C., Schultz, Kirk R., Qayed, Muna, Broglie, Larisa, Eapen, Mary, Yanik, Gregory A.

Get full text

Safety and feasibility of umbilical cord blood transplantation in children with neuronal ceroid lipofuscinosis: a retrospective study by Bauchat, Andrea, Polishchuk, Veronika, Fabrizio, Vanessa A, Brondon, Jennifer E, Page, Kristin M, Driscoll, Timothy A, Martin, Paul L, Mahadeo, Kris M, Kurtzberg, Joanne, Prasad, Vinod K

“…Ceroid lipofuscinosis neuronal (CLN) encompasses rare inherited neurodegenerative disorders that present in childhood with clinical features including…”
Get full text

Ethical considerations of using a single minor donor for three bone marrow harvests for three HLA‐matched siblings with primary immunodeficiency by Parikh, Suhag H., Pentz, Rebecca D., Haight, Ann, Adeli, Mehdi, Martin, Paul L., Driscoll, Timothy A., Page, Kristin, Kurtzberg, Joanne, Prasad, Vinod K., Barfield, Raymond C.

“…Allogeneic hematopoietic stem cell transplantation is curative for primary immunodeficiencies. Bone marrow from an unaffected human leukocyte antigen…”
Get full text

Myeloablative Transplantation using either Cord Blood or Bone Marrow leads to Immune Recovery, High Long-Term Donor Chimerism and Excellent Survival in Chronic Granulomatous Disease by Tewari, Priti, Martin, Paul L, Mendizabal, Adam, Parikh, Suhag H, Page, Kristin M, Driscoll, Timothy A, Malech, Harry L, Kurtzberg, Joanne, Prasad, Vinod K

“…The curative potential of hematopoietic stem cell transplantation in patients with chronic granulomatous disease depends on availability of a suitable donor,…”
Get full text

Augmentation of umbilical cord blood (UCB) transplantation with ex vivo–expanded UCB cells: results of a phase 1 trial using the AastromReplicell System by Jaroscak, Jennifer, Goltry, Kristin, Smith, Alan, Waters-Pick, Barbara, Martin, Paul L., Driscoll, Timothy A., Howrey, Richard, Chao, Nelson, Douville, Judy, Burhop, Sue, Fu, Pingfu, Kurtzberg, Joanne

“…Allogeneic stem cell transplantation with umbilical cord blood (UCB) cells is limited by the cell dose a single unit provides recipients. Ex vivo expansion is…”
Get full text

Therapeutic Monitoring of Voriconazole in Children Less Than Three Years of Age: A Case Report and Summary of Voriconazole Concentrations for Ten Children by Doby, Elizabeth H, Benjamin, Daniel K, Blaschke, Anne J, Ward, Robert M, Pavia, Andrew T, Martin, Paul L, Driscoll, Timothy A, Cohen-Wolkowiez, Michael, Moran, Cassandra

“…Voriconazole is the treatment of choice for invasive aspergillosis and its use is increasing in pediatrics. Minimal pharmacokinetic data exist in young…”
Get full text

Children Receiving Hematopoietic Stem Cell Transplantation are at Increased Risk of Onychocryptosis Requiring Surgical Management by Ezekian, Brian, Englum, Brian R, Gilmore, Brian F, Kim, Jina, Leraas, Harold J, Driscoll, Timothy A, Tracy, Elisabeth T, Rice, Henry E

“…At our institution, a high proportion of children with onychocryptosis (ingrown toenail) requiring surgical intervention were noted to have a history of…”
Get full text

Durable engraftment and correction of hematological abnormalities in children with congenital amegakaryocytic thrombocytopenia following myeloablative umbilical cord blood transplantation by Mahadeo, Kris M., Tewari, Priti, Parikh, Suhag H., Driscoll, Timothy A., Page, Kristin, Martin, Paul L., Kurtzberg, Joanne, Prasad, Vinod K.

“…The use of HSCT is the only potentially curative treatment for CAMT, but access is limited by the availability of suitable donors. We report five consecutive…”
Get full text

BACPTDP: a water-soluble camptothecin pro-drug with enhanced activity in hypoxic/acidic tumors by Adams, David J., Waud, William R., Wani, Mansukh C., Manikumar, Govindarajan, Flowers, James L., Driscoll, Timothy A., Morgan, Lee Roy

“…Hypoxia is a common feature of solid tumors. Up-regulation of hypoxia-inducing factor-1 (HIF-1) occurs in the majority of primary malignant tumors and in…”
Get full text

Ceramide generation by two distinct pathways in tumor necrosis factor α‐induced cell death by Dbaibo, Ghassan S, El-Assaad, Wissal, Krikorian, Armand, Liu, Bin, Diab, Karim, Idriss, Nadine Z, El-Sabban, Marwan, Driscoll, Timothy A, Perry, David K, Hannun, Yusuf A

“…Ceramide accumulation in the cell can occur from either hydrolysis of sphingomyelin or by de novo synthesis. In this study, we found that blocking de novo…”
Get full text

Durable Chimerism and Long-Term Survival after Unrelated Umbilical Cord Blood Transplantation for Pediatric Hemophagocytic Lymphohistiocytosis: A Single-Center Experience by Patel, Sachit A., Allewelt, Heather A., Troy, Jesse D., Martin, Paul L., Driscoll, Timothy A., Prasad, Vinod K., Kurtzberg, Joanne, Page, Kristin M., Parikh, Suhag H.

“…•Umbilical cord blood transplantation can provide durable engraftment in pediatric patients with hemophagocytic lymphohistiocytosis•Umbilical cord blood…”
Get full text

A Novel Reduced-Intensity Conditioning Regimen for Unrelated Umbilical Cord Blood Transplantation in Children with Nonmalignant Diseases by Parikh, Suhag H, Mendizabal, Adam, Benjamin, Cara L, Komanduri, Krishna V, Antony, Jeyaraj, Petrovic, Aleksandra, Hale, Gregory, Driscoll, Timothy A, Martin, Paul L, Page, Kristin M, Flickinger, Ketti, Moffet, Jerelyn, Niedzwiecki, Donna, Kurtzberg, Joanne, Szabolcs, Paul

“…Abstract Reduced-intensity conditioning (RIC) regimens have the potential to decrease transplantation-related morbidity and mortality. However, engraftment…”
Get full text