Search Results - "Driscoll, Mark D"

High-resolution microbiome analysis reveals exclusionary Klebsiella species competition in preterm infants at risk for necrotizing enterocolitis by Coleman, Spencer, Unterhauser, Katrin, Rezaul, Karim, Ledala, Nagender, Lesmes, Stephanie, Caimano, Melissa J., Zhou, Yanjiao, Jackson, Eric, Gratalo, Dawn, Driscoll, Mark D., Matson, Adam P.

“…Intestinal colonization with Klebsiella has been linked to necrotizing enterocolitis (NEC), but methods of analysis usually failed to discriminate Klebsiella…”
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Finding the right fit: evaluation of short-read and long-read sequencing approaches to maximize the utility of clinical microbiome data by Gehrig, Jeanette L, Portik, Daniel M, Driscoll, Mark D, Jackson, Eric, Chakraborty, Shreyasee, Gratalo, Dawn, Ashby, Meredith, Valladares, Ricardo

“…A long-standing challenge in human microbiome research is achieving the taxonomic and functional resolution needed to generate testable hypotheses about the…”
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High-throughput genotyping of single nucleotide polymorphisms with rolling circle amplification by Faruqi, A F, Hosono, S, Driscoll, M D, Dean, F B, Alsmadi, O, Bandaru, R, Kumar, G, Grimwade, B, Zong, Q, Sun, Z, Du, Y, Kingsmore, S, Knott, T, Lasken, R S

“…Single nucleotide polymorphisms (SNPs) are the foundation of powerful complex trait and pharmacogenomic analyses. The availability of large SNP databases,…”
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High accuracy genotyping directly from genomic DNA using a rolling circle amplification based assay by Alsmadi, Osama A, Bornarth, Carole J, Song, Wanmin, Wisniewski, Michele, Du, Jing, Brockman, Joel P, Faruqi, A Fawad, Hosono, Seiyu, Sun, Zhenyu, Du, Yuefen, Wu, Xiaohong, Egholm, Michael, Abarzúa, Patricio, Lasken, Roger S, Driscoll, Mark D

“…Rolling circle amplification of ligated probes is a simple and sensitive means for genotyping directly from genomic DNA. SNPs and mutations are interrogated…”
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Human Immunodeficiency Virus Type 1 Nucleocapsid Protein Can Prevent Self-Priming of Minus-Strand Strong Stop DNA by Promoting the Annealing of Short Oligonucleotides to Hairpin Sequences by Driscoll, M D, Hughes, S H

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Chicken Ovalbumin Upstream Promoter-Transcription Factor Interacts with Estrogen Receptor, Binds to Estrogen Response Elements and Half-Sites, and Inhibits Estrogen-induced Gene Expression by Klinge, Carolyn M., Silver, Bethany F., Driscoll, Mark D., Sathya, Ganesan, Bambara, Robert A., Hilf, Russell

“…Chicken ovalbumin upstream promoter-transcription factor (COUP-TF) was identified as a low abundance protein in bovine uterus that co-purified with estrogen…”
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Sequence Requirements for Estrogen Receptor Binding to Estrogen Response Elements by Driscoll, Mark D., Sathya, G., Muyan, Mesut, Klinge, Carolyn M., Hilf, Russell, Bambara, Robert A.

“…The estrogen receptor (ER) is a transcription factor that binds to a specific DNA sequence found in the regulatory regions of estrogen-responsive genes, called…”
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In Vitro Analysis of Human Immunodeficiency Virus Type 1 Minus-Strand Strong-Stop DNA Synthesis and Genomic RNA Processing by Driscoll, M D, Golinelli, M P, Hughes, S H

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The Effects of Estrogen-Responsive Element- and Ligand-Induced Structural Changes on the Recruitment of Cofactors and Transcriptional Responses by ERα and ERβ by Yi, Ping, Driscoll, Mark D, Huang, Jing, Bhagat, Sumedha, Hilf, Russell, Bambara, Robert A, Muyan, Mesut

“…Estrogen signaling is mediated by ERα and -β. ERs are converted from an inactive form to a transcriptionally active state through conformational changes…”
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An Explanation for Observed Estrogen Receptor Binding to Single-Stranded Estrogen-Responsive Element DNA by Driscoll, Mark D, Sathya, Ganesan, Saidi, Layla F, DeMott, Michael S, Hilf, Russell, Bambara, Robert A

“…Estrogen-inducible genes contain an enhancer called the estrogen response element (ERE), a double-stranded inverted repeat. The estrogen receptor (ER) is…”
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Fusion estrogen receptor proteins: toward the development of receptor-based agonists and antagonists by Muyan, Mesut, Yi, Ping, Sathya, Ganesan, Willmert, Leslie J., Driscoll, Mark D., Hilf, Russell, Bambara, Robert A.

“…Estrogen-induced signaling mediated by estrogen receptors (ERs) is also affected by aberrant ERs that act as constitutively active or dominant negative…”
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Footprint analysis of estrogen receptor binding to adjacent estrogen response elements by Driscoll, Mark D., Klinge, Carolyn M., Hilf, Russell, Bambara, Robert A.

“…Quantitative DNase I footprinting assays were employed to simultaneously measure the amount of estrogen receptor (ER) bound to each site in constructs…”
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Site-directed estrogen receptor antibodies stabilize 4-hydroxytamoxifen ligand, but not estradiol, and indicate ligand-specific differences in the recognition of estrogen response element DNA in vitro by Klinge, Carolyn M., Traish, Abdulmaged M., Driscoll, Mark D., Hilf, Russell, Bambara, Robert A.

“…Conformational differences between type I antiestrogen-liganded estrogen receptor and estradiol (E 2)-liganded estrogen receptor (ER) are thought to be…”
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