Search Results - "Drigo, Sandra"
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MicroRNA modulated networks of adaptive and innate immune response in pancreatic ductal adenocarcinoma
Published in PloS one (31-05-2019)“…Despite progress in treatment strategies, only ~24% of pancreatic ductal adenocarcinoma (PDAC) patients survive >1 year. Our goal was to elucidate deregulated…”
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2
Circulating miR-16-5p, miR-92a-3p, and miR-451a in Plasma from Lung Cancer Patients: Potential Application in Early Detection and a Regulatory Role in Tumorigenesis Pathways
Published in Cancers (01-08-2020)“…Background: Micro(mi)RNAs, potent gene expression regulators associated with tumorigenesis, are stable, abundant circulating molecules, and detectable in…”
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3
Comprehensive Genomic Profiling of Androgen-Receptor-Negative Canine Prostate Cancer
Published in International journal of molecular sciences (28-03-2019)“…Canine carcinomas have been considered natural models for human diseases; however, the genomic profile of canine prostate cancers (PCs) has not been explored…”
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4
Advances in the Molecular Landscape of Lung Cancer Brain Metastasis
Published in Cancers (24-01-2023)“…Lung cancer is one of the most frequent tumors that metastasize to the brain. Brain metastasis (BM) is common in advanced cases, being the major cause of…”
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5
Nuclear loss and cytoplasmic expression of androgen receptor in penile carcinomas: role as a driver event and as a prognosis factor
Published in Virchows Archiv : an international journal of pathology (01-11-2018)“…Androgen receptor (AR) is a member of the steroid and nuclear family receptor that acts as transcription factor. AR signaling plays pivotal role in the…”
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Down-Regulation of SLC8A1 as a Putative Apoptosis Evasion Mechanism by Modulation of Calcium Levels in Penile Carcinoma
Published in The Journal of urology (01-07-2015)“…Purpose The SLC8A1 gene, which encodes the Na+ /Ca2+ exchanger, has a key role in calcium homeostasis. Our previous gene expression oligoarray data revealed…”
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STEAP1 protein overexpression is an independent marker for biochemical recurrence in prostate carcinoma
Published in Histopathology (01-11-2013)“…Aims To investigate the prognostic value of expression levels of the genes STEAP1 and STEAP2, and of STEAP1 protein, in prostate carcinomas (PCa). Methods and…”
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Typical Lung Carcinoids with Metastasis: Potential Role of MicroRNAs in the Regulation of Adaptive Immunity Associated with Disease: a Case Study
Published in Cellular physiology and biochemistry (06-01-2021)“…Lung carcinoids are uncommon neuroendocrine tumours. Molecular features of lung carcinoids have been poorly defined. microRNAs (miRNAs) are potent gene…”
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9
Integrative miRNA and mRNA analysis in penile carcinomas reveals markers and pathways with potential clinical impact
Published in Oncotarget (28-02-2017)“…Penile carcinoma (PeCa) is an important public health issue in poor and developing countries, and has only recently been explored in terms of genetic and…”
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10
Differential Expression of Ribosomal Genes in Brain and Blood of Alzheimer's Disease Patients
Published in Current Alzheimer research (01-12-2015)“…Changes in rRNA and rDNA expression have been associated with cellular and organism aging and have been linked to Alzheimer's disease (AD) pathogenesis. In…”
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Discovery of Novel miRNAs in Colorectal Cancer: Potential Biological Roles and Clinical Utility
Published in Non-coding RNA (01-10-2023)“…Deregulated miRNAs are associated with colorectal cancer (CRC), with alterations depending on the tumor location. Novel tissue-specific miRNAs have been…”
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12
Defining Metabolic Rewiring in Lung Squamous Cell Carcinoma
Published in Metabolites (07-03-2019)“…Metabolomics based on untargeted flow infusion electrospray ionization high-resolution mass spectrometry (FIE-HRMS) can provide a snap-shot of metabolism in…”
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13
Common chromosomal imbalances and stemness-related protein expression markers in endometriotic lesions from different anatomical sites: the potential role of stem cells
Published in Human reproduction (Oxford) (01-11-2012)“…BACKGROUND Endometriosis is a multifactorial gynecological disease characterized by the presence of functional endometrium-like tissue in ectopic sites…”
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14
Immunological and Non-Immunological Effects of Cytokines and Chemokines in the Pathogenesis of Chronic Chagas Disease Cardiomyopathy
Published in Memórias do Instituto Oswaldo Cruz (01-07-2009)“…The pathogenesis of Chagas disease cardiomyopathy (CCC) is not well understood. Since studies show that myocarditis is more frequent during the advanced stages…”
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Deregulated microRNAs Are Associated with Patient Survival and Predicted to Target Genes That Modulate Lung Cancer Signaling Pathways
Published in Cancers (22-09-2020)“…(1) Background: Although the advances in diagnostic and treatment strategies, lung cancer remains the leading cause of cancer-related deaths, worldwide, with…”
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16
Immunohistochemical panel to characterize canine prostate carcinomas according to aberrant p63 expression
Published in PloS one (12-06-2018)“…An unusual variant of prostate adenocarcinoma (PC) expressing nuclear p63 in secretory cells instead of the typical basal expression has been reported in men…”
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17
A comprehensive characterization of cell cultures and xenografts derived from a human verrucous penile carcinoma
Published in Tumor biology (01-08-2016)“…This study aimed to establish and characterize primary cell cultures and xenografts derived from penile carcinoma (PeCa) in order to provide experimental…”
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18
Polymorphisms in the Gene for Lymphotoxin-αPredispose to Chronic Chagas Cardiomyopathy
Published in The Journal of infectious diseases (15-12-2007)“…Background. Chagas disease, caused by Trypanosoma cruzi infection, displays clinical heterogeneity and may be attributable to differential genetic…”
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BAT1, a Putative Anti-Inflammatory Gene, Is Associated with Chronic Chagas Cardiomyopathy
Published in The Journal of infectious diseases (15-05-2006)“…BackgroundIt is not understood why only a subset of individuals infected with Trypanosoma cruzi develop chronic Chagas cardiomyopathy (CCC). Patients with CCC…”
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20
Molecular Expression Profile Reveals Potential Biomarkers and Therapeutic Targets in Canine Endometrial Lesions
Published in PloS one (29-07-2015)“…Cystic endometrial hyperplasia (CEH), mucometra, and pyometra are common uterine diseases in intact dogs, with pyometra being a life threatening disease. This…”
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