Search Results - "Drifka, Cole"

Methods for Quantifying Fibrillar Collagen Alignment by Liu, Yuming, Keikhosravi, Adib, Mehta, Guneet S, Drifka, Cole R, Eliceiri, Kevin W

“…Recent evidence has implicated collagen, particularly fibrillar collagen, in a number of diseases ranging from osteogenesis imperfecta and asthma to breast and…”
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Highly aligned stromal collagen is a negative prognostic factor following pancreatic ductal adenocarcinoma resection by Drifka, Cole R, Loeffler, Agnes G, Mathewson, Kara, Keikhosravi, Adib, Eickhoff, Jens C, Liu, Yuming, Weber, Sharon M, Kao, W John, Eliceiri, Kevin W

“…Risk factors for pancreatic ductal adenocarcinoma (PDAC) progression after surgery are unclear, and additional prognostic factors are needed to inform…”
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Periductal stromal collagen topology of pancreatic ductal adenocarcinoma differs from that of normal and chronic pancreatitis by Drifka, Cole R, Tod, Jo, Loeffler, Agnes G, Liu, Yuming, Thomas, Gareth J, Eliceiri, Kevin W, Kao, W John

“…Pancreatic ductal adenocarcinoma continues to be one of the most difficult diseases to manage with one of the highest cancer mortality rates. This is due to…”
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Collagen organization of renal cell carcinoma differs between low and high grade tumors by Best, Sara L, Liu, Yuming, Keikhosravi, Adib, Drifka, Cole R, Woo, Kaitlin M, Mehta, Guneet S, Altwegg, Marie, Thimm, Terra N, Houlihan, Matthew, Bredfeldt, Jeremy S, Abel, E Jason, Huang, Wei, Eliceiri, Kevin W

“…The traditional pathologic grading for human renal cell carcinoma (RCC) has low concordance between biopsy and surgical specimen. There is a need to…”
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A bioengineered heterotypic stroma-cancer microenvironment model to study pancreatic ductal adenocarcinoma by Drifka, Cole R, Eliceiri, Kevin W, Weber, Sharon M, Kao, W John

“…Interactions between neoplastic epithelial cells and components of a reactive stroma in pancreatic ductal adenocarcinoma (PDAC) are of key significance behind…”
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A subset of myofibroblastic cancer-associated fibroblasts regulate collagen fiber elongation, which is prognostic in multiple cancers by Hanley, Christopher J, Noble, Fergus, Ward, Matthew, Bullock, Marc, Drifka, Cole, Mellone, Massimiliano, Manousopoulou, Antigoni, Johnston, Harvey E, Hayden, Annette, Thirdborough, Steve, Liu, Yuming, Smith, David M, Mellows, Toby, Kao, W John, Garbis, Spiros D, Mirnezami, Alex, Underwood, Tim J, Eliceiri, Kevin W, Thomas, Gareth J

“…Collagen structure has been shown to influence tumor cell invasion, metastasis and clinical outcome in breast cancer. However, it remains unclear how it…”
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Comparison of Picrosirius Red Staining With Second Harmonic Generation Imaging for the Quantification of Clinically Relevant Collagen Fiber Features in Histopathology Samples by Drifka, Cole R., Loeffler, Agnes G., Mathewson, Kara, Mehta, Guneet, Keikhosravi, Adib, Liu, Yuming, Lemancik, Stephanie, Ricke, William A., Weber, Sharon M., Kao, W. John, Eliceiri, Kevin W.

“…Stromal collagen alignment has been shown to have clinical significance in a variety of cancers and in other diseases accompanied by fibrosis. While much of…”
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Navigating the Collagen Jungle: The Biomedical Potential of Fiber Organization in Cancer by Ouellette, Jonathan N, Drifka, Cole R, Pointer, Kelli B, Liu, Yuming, Lieberthal, Tyler J, Kao, W John, Kuo, John S, Loeffler, Agnes G, Eliceiri, Kevin W

“…Recent research has highlighted the importance of key tumor microenvironment features, notably the collagen-rich extracellular matrix (ECM) in characterizing…”
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Quantification of collagen organization in histopathology samples using liquid crystal based polarization microscopy by Keikhosravi, Adib, Liu, Yuming, Drifka, Cole, Woo, Kaitlin M, Verma, Amitabh, Oldenbourg, Rudolf, Eliceiri, Kevin W

“…A number of histopathology studies have utilized the label free microscopy method of Second Harmonic Generation (SHG) to investigate collagen organization in…”
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Human pancreatic stellate cells modulate 3D collagen alignment to promote the migration of pancreatic ductal adenocarcinoma cells by Drifka, Cole R., Loeffler, Agnes G., Esquibel, Corinne R., Weber, Sharon M., Eliceiri, Kevin W., Kao, W. John

“…A hallmark of pancreatic ductal adenocarcinoma (PDAC) is the ability for cancer cells to aggressively infiltrate and navigate through a dense stroma during the…”
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Transglutaminase-2 Mediates the Biomechanical Properties of the Colorectal Cancer Tissue Microenvironment that Contribute to Disease Progression by Delaine-Smith, Robin, Wright, Nicola, Hanley, Chris, Hanwell, Rebecca, Bhome, Rahul, Bullock, Marc, Drifka, Cole, Eliceiri, Kevin, Thomas, Gareth, Knight, Martin, Mirnezami, Alex, Peake, Nicholas

“…Colorectal cancer is the third most common cancer worldwide, and the fourth leading cause of malignancy-related mortality. This highlights the need to…”
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Studying the role of stromal collagen alignment in pancreatic ductal adenocarcinoma via clinical histopathology and 3D tumor models by Drifka, Cole R

“…Pancreatic ductal adenocarcinoma (PDAC) prognosis remains poor due to aggressive invasion and metastasis, late diagnosis, and resistance to current…”
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