Search Results - "Driessen, Niels J B"

Tissue engineering of human heart valve leaflets: a novel bioreactor for a strain-based conditioning approach by Mol, Anita, Driessen, Niels J B, Rutten, Marcel C M, Hoerstrup, Simon P, Bouten, Carlijn V C, Baaijens, Frank P T

“…Current mechanical conditioning approaches for heart valve tissue engineering concentrate on mimicking the opening and closing behavior of the leaflets, either…”
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Effect of Strain Magnitude on the Tissue Properties of Engineered Cardiovascular Constructs by Boerboom, Ralf A., Rubbens, Mirjam P., Driessen, Niels J. B., Bouten, Carlijn V. C., Baaijens, Frank P. T.

“…Mechanical loading is a powerful regulator of tissue properties in engineered cardiovascular tissues. To ultimately regulate the biochemical processes, it is…”
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Remodelling of the angular collagen fiber distribution in cardiovascular tissues by Driessen, Niels J. B., Cox, Martijn A. J., Bouten, Carlijn V. C., Baaijens, Frank P. T.

“…Understanding collagen fiber remodelling is desired to optimize the mechanical conditioning protocols in tissue-engineering of load-bearing cardiovascular…”
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Microstructurally Motivated Model of the Mechanical Behavior of Tissue Engineered Blood Vessels by Dahl, Shannon L. M, Vaughn, Megann E, Hu, Jin-Jia, Driessen, Niels J. B, Baaijens, Frank P. T, Humphrey, Jay D, Niklason, Laura E

“…Mechanical models have potential to guide the development and use of engineered blood vessels as well as other engineered tissues. This paper presents a…”
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A structural constitutive model for collagenous cardiovascular tissues incorporating the angular fiber distribution by Driessen, Niels J B, Bouten, Carlijn V C, Baaijens, Frank P T

“…Accurate constitutive models are required to gain further insight into the mechanical behavior of cardiovascular tissues. In this study, a structural…”
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Autologous human tissue-engineered heart valves : Prospects for systemic application by MOL, Anita, RUTTEN, Marcel C. M, DRIESSEN, Niels J. B, BOUTEN, Carlijn V. C, ZÜND, Gregor, BAAIJENS, Frank P. T, HOERSTRUP, Simon P

“…Tissue engineering represents a promising approach for the development of living heart valve replacements. In vivo animal studies of tissue-engineered…”
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Modeling the mechanics of tissue-engineered human heart valve leaflets by Driessen, Niels J.B, Mol, Anita, Bouten, Carlijn V.C, Baaijens, Frank P.T

“…Abstract Mathematical models can provide valuable information to assess and evaluate the mechanical behavior of tissue-engineered constructs. In this study, a…”
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Finite element model of mechanically induced collagen fiber synthesis and degradation in the aortic valve by Boerboom, Ralf A, Driessen, Niels J B, Bouten, Carlijn V C, Huyghe, Jacques M, Baaijens, Frank P T

“…Tissue-engineered trileaflet aortic valves are a promising alternative to current valve replacements. However, the mechanical properties of these valves are…”
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Nondestructive and noninvasive assessment of mechanical properties in heart valve tissue engineering by Kortsmit, Jeroen, Driessen, Niels J B, Rutten, Marcel C M, Baaijens, Frank P T

“…Despite recent progress, mechanical behavior of tissue-engineered heart valves still needs improvement when native aortic valves are considered as a benchmark…”
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Mechanical characterization of anisotropic planar biological soft tissues using finite indentation: Experimental feasibility by Cox, Martijn A.J, Driessen, Niels J.B, Boerboom, Ralf A, Bouten, Carlijn V.C, Baaijens, Frank P.T

“…Abstract Heart valve tissue engineering offers a promising alternative for current treatment and replacement strategies, e.g., synthetic or bioprosthetic heart…”
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Stress related collagen ultrastructure in human aortic valves—implications for tissue engineering by Balguid, Angelique, Driessen, Niels J.B, Mol, Anita, Schmitz, Joep P.J, Verheyen, Fons, Bouten, Carlijn V.C, Baaijens, Frank P.T

“…Abstract Understanding the response of tissue structures to mechanical stress is crucial for optimization of mechanical conditioning protocols in the field of…”
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Improved prediction of the collagen fiber architecture in the aortic heart valve by Driessen, Niels J B, Bouten, Carlijn V C, Baaijens, Frank P T

“…Living tissues show an adaptive response to mechanical loading by changing their internal structure and morphology. Understanding this response is essential…”
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Computational analyses of mechanically induced collagen fiber remodeling in the aortic heart valve by Driessen, Niels J, Boerboom, Ralf A, Huyghe, Jacques M, Bouten, Carlijn V, Baaijens, Frank P

“…To optimize the mechanical properties and integrity of tissue-engineered aortic heart valves, it is necessary to gain insight into the effects of mechanical…”
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Mechanical characterization of anisotropic planar biological soft tissues using large indentation: a computational feasibility study by Cox, Martijn A J, Driessen, Niels J B, Bouten, Carlijn V C, Baaijens, Frank P T

“…Traditionally, the complex mechanical behavior of planar soft biological tissues is characterized by (multi)axial tensile testing. While uniaxial tests do not…”
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The non-linear mechanical properties of soft engineered biological tissues determined by finite spherical indentation by Cox, Martijn A.J., Gawlitta, Debby, Driessen, Niels J.B., Oomens, Cees W.J., Baaijens, Frank P.T.

“…The mechanical properties of soft biological tissues in general and early stage engineered tissues in particular limit the feasibility of conventional tensile…”
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