Search Results - "Driesen, Naomi R."
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Impaired Tuning of Neural Ensembles and the Pathophysiology of Schizophrenia: A Translational and Computational Neuroscience Perspective
Published in Biological psychiatry (1969) (15-05-2017)“…Abstract The functional optimization of neural ensembles is central to human higher cognitive functions. When the functions through which neural activity is…”
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Brain Connectivity Related to Working Memory Performance
Published in The Journal of neuroscience (20-12-2006)“…Several brain areas show signal decreases during many different cognitive tasks in functional imaging studies, including the posterior cingulate cortex (PCC)…”
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N -Methyl-D-Aspartate Receptor Antagonist Effects on Prefrontal Cortical Connectivity Better Model Early Than Chronic Schizophrenia
Published in Biological psychiatry (1969) (15-03-2015)“…Abstract Background Prefrontal cortex (PFC) function contributes to schizophrenia onset and progression. However, little is known about neural mechanisms…”
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NMDA receptor function in large-scale anticorrelated neural systems with implications for cognition and schizophrenia
Published in Proceedings of the National Academy of Sciences - PNAS (09-10-2012)“…Glutamatergic neurotransmission mediated by N -methyl- d -aspartate (NMDA) receptors is vital for the cortical computations underlying cognition and might be…”
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The Impact of NMDA Receptor Blockade on Human Working Memory-Related Prefrontal Function and Connectivity
Published in Neuropsychopharmacology (New York, N.Y.) (01-12-2013)“…Preclinical research suggests that N-methyl-D-aspartate glutamate receptors (NMDA-Rs) have a crucial role in working memory (WM). In this study, we…”
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Altered functional connectivity and low-frequency signal fluctuations in early psychosis and genetic high risk
Published in Schizophrenia research (01-08-2019)“…Studying individuals at increased genetic risk for schizophrenia may generate important theories regarding the emergence of the illness. In this investigation,…”
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Impairment of Working Memory Maintenance and Response in Schizophrenia: Functional Magnetic Resonance Imaging Evidence
Published in Biological psychiatry (1969) (15-12-2008)“…Background Comparing prefrontal cortical activity during particular phases of working memory in healthy subjects and individuals diagnosed with schizophrenia…”
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A robust and reproducible connectome fingerprint of ketamine is highly associated with the connectomic signature of antidepressants
Published in Neuropsychopharmacology (New York, N.Y.) (01-01-2021)“…Over the past decade, various N-methyl-D-aspartate modulators have failed in clinical trials, underscoring the challenges of developing novel rapid-acting…”
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Connectivity, pharmacology, and computation: toward a mechanistic understanding of neural system dysfunction in schizophrenia
Published in Frontiers in psychiatry (24-12-2013)“…Neuropsychiatric diseases such as schizophrenia and bipolar illness alter the structure and function of distributed neural networks. Functional neuroimaging…”
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Hypoglycemia reduces the blood-oxygenation level dependent signal in primary auditory and visual cortex: A functional magnetic resonance imaging study
Published in Journal of neuroscience research (15-02-2007)“…Studies of the effects of hypoglycemia on the brain using neurocognitive testing have suggested that mainly complex functions subserved by secondary and…”
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Relationship of resting brain hyperconnectivity and schizophrenia-like symptoms produced by the NMDA receptor antagonist ketamine in humans
Published in Molecular psychiatry (01-11-2013)“…N -methyl-D-aspartate glutamate receptor (NMDA-R) antagonists produce schizophrenia-like positive and negative symptoms in healthy human subjects. Preclinical…”
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Reaction Time Impairment in Insulin-Dependent Diabetes: Task Complexity, Blood Glucose Levels, and Individual Differences
Published in Neuropsychology (01-04-1995)“…The effects of hypoglycemia on cognitive processing speed as measured by reaction time (RT) were evaluated in 25 adults (13 women and 12 men) with…”
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Connectivity, Pharmacology and Computation: Towards a Mechanistic Understanding of Neural System Dysfunction in Schizophrenia
Published in Frontiers in psychiatry (01-12-2013)“…Neuropsychiatric diseases such as schizophrenia and bipolar illness alter the structure and function of distributed neural networks. Functional neuroimaging…”
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Individual differences in neurobehavioral disruption during mild and moderate hypoglycemia in adults with IDDM
Published in Diabetes (New York, N.Y.) (01-12-1994)“…Individual differences in neurobehavioral disruption during mild and moderate hypoglycemia in adults with IDDM. L A Gonder-Frederick , D J Cox , N R Driesen ,…”
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Reliability of driving performance during moderate hypoglycemia in adults with IDDM
Published in Diabetes care (01-11-1994)Get full text
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Individual differences in neurobehavioral disruption during mild and moderate hypoglycemia in adults with IDDM
Published in Diabetes (New York, N.Y.) (01-12-1994)“…This study investigated the neurobehavioral effects of mild and moderate hypoglycemia in adults with insulin-dependent diabetes mellitus (IDDM). On 2…”
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