Search Results - "Dreyfus, C"
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Development of ISB 1442, a CD38 and CD47 bispecific biparatopic antibody innate cell modulator for the treatment of multiple myeloma
Published in Nature communications (06-03-2024)“…Antibody engineering can tailor the design and activities of therapeutic antibodies for better efficiency or other advantageous clinical properties. Here we…”
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Scaling the α-relaxation time of supercooled fragile organic liquids
Published in The European physical journal. B, Condensed matter physics (01-12-2004)“…It was shown recently that the structural alpha-relaxation time tau of supercooled o-terphenyl depends on a single control parameter Gamma, which is the…”
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3
Brain-Derived Neurotrophic Factor in Astrocytes, Oligodendrocytes, and Microglia/Macrophages after Spinal Cord Injury
Published in Neurobiology of disease (01-12-2000)“…Recent studies suggest that the injured adult spinal cord responds to brain-derived neurotrophic factor (BDNF) and neurotrophin-3 (NT3) with enhanced neuron…”
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4
Temperature and pressure study of Brillouin transverse modes in the organic glass-forming liquid orthoterphenyl
Published in Physical review. E, Statistical physics, plasmas, fluids, and related interdisciplinary topics (01-07-2003)“…Transverse Brillouin spectra of orthoterphenyl are measured in the (250-305 K; 0.1-100 MPa) temperature-pressure range, which corresponds to the supercooled…”
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Brain-Derived Neurotrophic Factor Rapidly Enhances Synaptic Transmission in Hippocampal Neurons via Postsynaptic Tyrosine Kinase Receptors
Published in Proceedings of the National Academy of Sciences - PNAS (15-08-1995)“…Although neurotrophins are primarily associated with long-term effects on neuronal survival and differentiation, recent studies have shown that acute changes…”
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Astrocyte-Derived BDNF Supports Myelin Protein Synthesis after Cuprizone-Induced Demyelination
Published in The Journal of neuroscience (11-06-2014)Get full text
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7
Oligodendrocytes as providers of growth factors
Published in Journal of neuroscience research (15-06-2002)“…Glial cells recently are being appreciated as supporters of brain neurons. This review addresses their role as growth factor providers. While the function of…”
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Concern about Justifying the Release of Genomic Data as a Civil Right
Published in American journal of human genetics (05-07-2018)Get full text
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9
Regulation of Topographic Projection in the Brain: Elf-1 in the Hippocamposeptal System
Published in Proceedings of the National Academy of Sciences - PNAS (01-10-1996)“…The hippocampus and septum play central roles in one of the most important spheres of brain function: learning and memory. Although their topographic…”
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Clinical Integration of Next Generation Sequencing: Coverage and Reimbursement Challenges
Published in The Journal of law, medicine & ethics (2014)“…Public and private payers face complex decisions regarding whether, when, and how to cover and reimburse for next generation sequencing (NGS)‐based tests. Yet…”
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Disruptive Influences on Research in Academic Pathology Departments: Proposed Changes to the Common Rule Governing Informed Consent for Research Use of Biospecimens and to Rules Governing Return of Research Results
Published in The American journal of pathology (01-01-2017)“…Academic pathology departments will be dramatically affected by proposed United States federal government regulatory initiatives. Pathology research will be…”
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Regional and cell-specific expression of GDNF in rat brain
Published in Experimental neurology (01-12-1993)“…The survival of ventral mesencephalic substantia nigra (SN) dopamine neurons, which degenerate in Parkinson's disease, is enhanced by glial cells in vitro. The…”
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Return of Individual Research Results: A Guide for Biomedical Researchers Utilizing Human Biospecimens
Published in The American journal of pathology (01-05-2020)“…The recent movement toward returning individual research results to study subjects/participants generates ethical and legal challenges for laboratories…”
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Disruptive Influences on Research in Academic Pathology Departments
Published in The American journal of pathology (2017)“…Academic pathology departments will be dramatically affected by proposed United States federal government regulatory initiatives. Pathology research will be…”
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Glial Cell Line-Derived Neurotrophic Factor Promotes the Survival and Morphologic Differentiation of Purkinje Cells
Published in Proceedings of the National Academy of Sciences - PNAS (26-09-1995)“…Glial cell line-derived neurotrophic factor (GDNF) promotes survival of midbrain dopaminergic neurons and motoneurons. Expression of GDNF mRNA in cerebellum…”
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The Trophic Role of Oligodendrocytes in the Basal Forebrain
Published in The Journal of neuroscience (02-07-2003)“…Traditionally, the primary function of oligodendrocytes (OLGs) in the CNS has been considered to be myelination. Here, we investigated whether OLGs may play a…”
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NGF gene expression in actively growing brain glia
Published in The Journal of neuroscience (01-02-1991)“…Previous work suggested that brain NGF acts locally on cells adjacent to sites of synthesis, in addition to any putative actions on distant, projecting…”
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Differential actions of neurotrophins in the locus coeruleus and basal forebrain
Published in Experimental neurology (01-01-1993)“…The neurotrophin gene family, including nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3), and NT-4/NT-5, supports the…”
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NGF and excitatory neurotransmitters regulate survival and morphogenesis of cultured cerebellar Purkinje cells
Published in The Journal of neuroscience (01-02-1991)“…The development of cerebellar Purkinje cells is subject to regulation by multiple epigenetic signals. To define mechanisms by which trophic and presynaptic…”
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Unexpected effect of internal degrees of freedom on transverse phonons in supercooled liquids
Published in Europhysics letters (01-02-2006)“…We show experimentally that in a supercooled liquid composed of molecules with internal degrees of freedom the internal modes contribute to the…”
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