Search Results - "Dreyer, ZoAnn E."
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FLT3 inhibitor lestaurtinib plus chemotherapy for newly diagnosed KMT2A-rearranged infant acute lymphoblastic leukemia: Children’s Oncology Group trial AALL0631
Published in Leukemia (01-05-2021)“…Infants with KMT2A ‐rearranged acute lymphoblastic leukemia ( KMT2A -r ALL) have a poor prognosis. KMT2A -r ALL overexpresses FLT3, and the FLT3 inhibitor…”
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Hyaluronan Synthase 3 Variant and Anthracycline-Related Cardiomyopathy: A Report From the Children's Oncology Group
Published in Journal of clinical oncology (01-03-2014)“…The strong dose-dependent association between anthracyclines and cardiomyopathy is further exacerbated by the co-occurrence of cardiovascular risk factors…”
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KMT2A partner genes in infant acute lymphoblastic leukemia have prognostic significance and correlate with age, white blood cell count, sex, and central nervous system involvement: a Children's Oncology Group P9407 trial study
Published in Haematologica (Roma) (01-10-2023)Get full text
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Gene expression profiles predictive of outcome and age in infant acute lymphoblastic leukemia: a Children's Oncology Group study
Published in Blood (23-02-2012)“…Gene expression profiling was performed on 97 cases of infant ALL from Children's Oncology Group Trial P9407. Statistical modeling of an outcome predictor…”
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Intensified chemotherapy without SCT in infant ALL: Results from COG P9407 (Cohort 3)
Published in Pediatric blood & cancer (01-03-2015)“…Background Infants with acute lymphoblastic leukemia (ALL) present with aggressive disease and a poor prognosis. Early relapse within 6–9 months of diagnosis…”
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Analysis of the Role of Hematopoietic Stem-Cell Transplantation in Infants With Acute Lymphoblastic Leukemia in First Remission and MLL Gene Rearrangements: A Report From the Children's Oncology Group
Published in Journal of clinical oncology (10-01-2011)“…Although the majority of children with acute lymphoblastic leukemia (ALL) are cured with current therapy, the event-free survival (EFS) of infants with ALL,…”
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Potent obatoclax cytotoxicity and activation of triple death mode killing across infant acute lymphoblastic leukemia
Published in Blood (04-04-2013)“…Survival in infants younger than 1 year who have acute lymphoblastic leukemia (ALL) is inferior whether MLL is rearranged (R) or germline (G). MLL…”
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Nonmelanoma Skin Cancer in Survivors of Childhood and Adolescent Cancer: A Report From the Childhood Cancer Survivor Study
Published in Journal of clinical oncology (01-06-2005)“…Nonmelanoma skin cancer (NMSC) has become the most common type of cancer in many populations throughout the world. Ultraviolet and ionizing radiation are known…”
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Human Papillomavirus Vaccination in Female Pediatric Cancer Survivors
Published in Journal of pediatric & adolescent gynecology (01-10-2012)“…Abstract Study Objective Survivors of childhood malignancy may be at increased risk for HPV infection for biological and cognitive/behavioral reasons. HPV…”
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Comparison of height and weight after 12 vs. 18 Gy cranial radiation therapy in pediatric acute lymphoblastic leukemia (ALL) patients
Published in Advances in radiation oncology (01-04-2017)“…Abstract Purpose To compare the effect of 12 versus 18 Gy cranial radiation therapy (RT) on height and weight indices among pediatric patients with acute…”
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CELF4 Variant and Anthracycline-Related Cardiomyopathy: A Children's Oncology Group Genome-Wide Association Study
Published in Journal of clinical oncology (10-03-2016)“…Interindividual variability in the dose-dependent association between anthracyclines and cardiomyopathy suggests that genetic susceptibility could play a role…”
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Association of GSTM1 null variant with anthracycline‐related cardiomyopathy after childhood cancer—A Children's Oncology Group ALTE03N1 report
Published in Cancer (01-09-2020)“…Background Anthracycline‐related cardiomyopathy is a leading cause of late morbidity in childhood cancer survivors. Glutathione S‐transferases (GSTs) are a…”
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The Population Pharmacokinetics of High-Dose Methotrexate in Infants with Acute Lymphoblastic Leukemia Highlight the Need for Bedside Individualized Dose Adjustment: A Report from the Children’s Oncology Group
Published in Clinical pharmacokinetics (01-07-2019)“…Background Infants with acute lymphoblastic leukemia (ALL) treated with high-dose methotrexate may have reduced methotrexate clearance (CL) due to renal…”
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Scoliosis in Children Treated With Photon Craniospinal Irradiation for Medulloblastoma
Published in International journal of radiation oncology, biology, physics (01-03-2021)“…Scoliosis is a well-recognized complication after abdominal radiation therapy but not reported frequently after craniospinal irradiation (CSI). We examined the…”
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Disparities in Neurotoxicity Risk and Outcomes among Pediatric Acute Lymphoblastic Leukemia Patients
Published in Clinical cancer research (15-10-2018)“…Methotrexate chemotherapy can be associated with neurologic complications during therapy and long-term neurologic deficits. This study evaluated demographic…”
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Philadelphia chromosome-positive pre-B lymphoblastic leukemia presenting as acute hepatic failure in a pediatric patient
Published in Pediatric hematology and oncology (15-08-2022)Get full text
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Determinants of survival after first relapse of acute lymphoblastic leukemia: a Children’s Oncology Group study
Published in Leukemia (11-09-2024)“…Limited prognostic factors have been associated with overall survival (OS) post-relapse in childhood Acute Lymphoblastic Leukemia (ALL). Patients enrolled on…”
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Targeting EIF4E signaling with ribavirin in infant acute lymphoblastic leukemia
Published in Oncogene (28-03-2019)“…The poor outcomes in infant acute lymphoblastic leukemia (ALL) necessitate new treatments. Here we discover that EIF4E protein is elevated in most cases of…”
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Molecular monitoring of 8p11 myeloproliferative syndrome in an infant
Published in Journal of pediatric hematology/oncology (01-11-2009)“…The 8p11 myeloproliferative syndrome is a rare hematologic malignancy derived from a pluripotent hematopoietic stem cell associated with rearrangements…”
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