Search Results - "Dreyer, Sandra D."

Mutations in LMX1B cause abnormal skeletal patterning and renal dysplasia in nail patella syndrome by Dreyer, Sandra D, Zhou, Guang, Baldini, Antonio, Winterpacht, Andreas, Zabel, Bernhard, Cole, William, Johnson, Randy L, Lee, Brendan

“…The LIM-homeodomain protein Lmx1b plays a central role in dorso-ventral patterning of the vertebrate limb. Targeted disruption of Lmx1b results in skeletal…”
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Lmx1b expression during joint and tendon formation: localization and evaluation of potential downstream targets by Dreyer, Sandra D., Naruse, Takuji, Morello, Roy, Zabel, Bernhard, Winterpacht, Andreas, Johnson, Randy L., Lee, Brendan, Oberg, Kerby C.

“…The tetrapod limb exhibits distinct dorsoventral joint, tendon, and muscle asymmetry. The LIM-homeodomain transcription factor, Lmx1b, is required to achieve…”
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Regulation of glomerular basement membrane collagen expression by LMX1B contributes to renal disease in nail patella syndrome by Lee, Brendan, Morello, Roy, Zhou, Guang, Dreyer, Sandra D, Harvey, Scott J, Ninomiya, Yoshifumi, Thorner, Paul S, Miner, Jeffrey H, Cole, William, Winterpacht, Andreas, Zabel, Bernhard, Oberg, Kerby C

“…Basement membrane (BM) morphogenesis is critical for normal kidney function. Heterotrimeric type IV collagen, composed of different combinations of six…”
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Mutation Analysis of LMX1B Gene in Nail-Patella Syndrome Patients by McIntosh, Iain, Dreyer, Sandra D., Clough, Mark V., Dunston, Jennifer A., Eyaid, Wafa'a, Roig, Carmen M., Montgomery, Tara, Ala-Mello, Sirpa, Kaitila, Ilkka, Winterpacht, Andreas, Zabel, Bernhard, Frydman, Moshe, Cole, William G., Francomano, Clair A., Lee, Brendan

“…Nail-patella syndrome (NPS), a pleiotropic disorder exhibiting autosomal dominant inheritance, has been studied for >100 years. Recent evidence shows that NPS…”
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LMX1B transactivation and expression in nail-patella syndrome by DREYER, S. D, MORELLO, R, GERMAN, M. S, ZABEL, B, WINTERPACHT, A, LUNSTRUM, G. P, HORTON, W. A, OBERG, K. C, LEE, B

“…Lmx1b, a member of the LIM homeodomain protein family, is essential for the specification of dorsal limb fates at the zeugopodal and autopodal level in…”
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Cloning, characterization, and chromosomal assignment of the human ortholog of murine Zfp-37, a candidate gene for Nager syndrome by Dreyer, S D, Zhou, L, Machado, M A, Horton, W A, Zabel, B, Winterpacht, A, Lee, B

“…In an effort to identify putative transcription factors involved in chondrocyte differentiation during human endochondral bone formation, a human fetal…”
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The long and the short of it: developmental genetics of the skeletal dysplasias by Dreyer, Sandra D, Zhou, Guang, Lee, Brendan

“…The skeletal dysplasias are a large heterogeneous group of genetic conditions characterized by abnormal shape, growth, or integrity of bones. Often, there may…”
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The long and the short of it: developmental genetics of the skeletal dysplasias by Dreyer, Sandra D, Zhou, Guang, Lee, Brendan

“…The skeletal dysplasias are a large heterogeneous group of genetic conditions characterized by abnormal shape, growth, or integrity of bones. Often, there may…”
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The Centromeric/Nucleolar Chromatin Protein ZFP-37 May Function to Specify Neuronal Nuclear Domains by Payen, Emmanuel, Verkerk, Ton, Michalovich, Dave, Dreyer, Sandra D., Winterpacht, Andreas, Lee, Brendan, De Zeeuw, Chris I., Grosveld, Frank, Galjart, Niels

“…Murine ZFP-37 is a member of the large family of C2H2 type zinc finger proteins. It is characterized by a truncated NH2-terminal Krüppel-associated box and is…”
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The long and the short of it: developmental genetics of the skeletal dysplasias: Section Editor: Roderick R McInnes
e‐mail: mcinnes@sickkids.on.ca by Dreyer, Sandra D, Zhou, Guang, Lee, Brendan

“…The skeletal dysplasias are a large heterogeneous group of genetic conditions characterized by abnormal shape, growth, or integrity of bones. Often, there may…”
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Isolation, Characterization, and Mapping of a Zinc Finger Gene, ZFP95, Containing Both a SCAN Box and an Alternatively Spliced KRAB A Domain by Dreyer, Sandra D., Zheng, Qiping, Zabel, Bernhard, Winterpacht, Andreas, Lee, Brendan

“…A new zinc finger gene of the Krüppel family was identified by screening a human fetal cartilage cDNA library with degenerate oligonucleotides. Sequence…”
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