Search Results - "Drexhage, Roosmarijn C"
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The immune theory of psychiatric diseases: a key role for activated microglia and circulating monocytes
Published in Journal of leukocyte biology (01-11-2012)“…Review on the key role for activated microglia and monocytes in the pathogenesis of bipolar disorder and schizophrenia. This review describes a key role for…”
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The mononuclear phagocyte system and its cytokine inflammatory networks in schizophrenia and bipolar disorder
Published in Expert review of neurotherapeutics (01-01-2010)“…This review describes patients with schizophrenia and bipolar disorder. In such patients, a high inflammatory set point of circulating monocytes at the…”
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Clinical performance of a novel and rapid bioassay for detection of thyroid-stimulating immunoglobulins in Graves' orbitopathy patients: a comparison with two commonly used immunoassays
Published in Frontiers in endocrinology (Lausanne) (27-09-2024)“…For the selective detection of thyroid-stimulating hormone receptor antibodies with stimulating properties (thyroid-stimulating immunoglobulins; TSI), a novel…”
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An Inflammatory Gene-Expression Fingerprint in Monocytes of Autoimmune Thyroid Disease Patients
Published in The journal of clinical endocrinology and metabolism (01-04-2010)“…Context: In monocytes of patients with autoimmune diabetes, we recently identified a gene expression fingerprint of two partly overlapping gene clusters, a…”
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Increased level of serum cytokines, chemokines and adipokines in patients with schizophrenia is associated with disease and metabolic syndrome
Published in Psychoneuroendocrinology (01-12-2012)“…Summary At present there are strong indications of a shared vulnerability factor for schizophrenia (SZ), diabetes and the metabolic syndrome (metS). In this…”
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Arginine or Hypertonic Saline–Stimulated Copeptin to Diagnose AVP Deficiency
Published in The New England journal of medicine (16-11-2023)“…Testing with hypertonic-saline stimulation was superior to testing with arginine stimulation in the diagnosis of arginine vasopressin deficiency…”
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The activation of monocyte and T cell networks in patients with bipolar disorder
Published in Brain, behavior, and immunity (01-08-2011)“…Highlights ► This manuscript describes the newest T lymphocyte subsets in patients with bipolar disorder and relate these to the classical subsets of the T…”
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Inflammatory gene expression in monocytes of patients with schizophrenia: overlap and difference with bipolar disorder. A study in naturalistically treated patients
Published in The international journal of neuropsychopharmacology (01-11-2010)“…Accumulating evidence indicates an activated inflammatory response system as a vulnerability factor for schizophrenia (SZ) and bipolar disorder (BD). We aimed…”
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An activated set point of T-cell and monocyte inflammatory networks in recent-onset schizophrenia patients involves both pro- and anti-inflammatory forces
Published in The international journal of neuropsychopharmacology (01-07-2011)“…We recently described a pro-inflammatory gene expression signature in the monocytes of 60% of patients with recent-onset schizophrenia (SCZ). Here we…”
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Relationship between clinical features and inflammation-related monocyte gene expression in bipolar disorder - towards a better understanding of psychoimmunological interactions
Published in Bipolar disorders (01-03-2014)“…Objectives Existing and previously published datasets were examined for associations between illness and treatment characteristics and monocyte…”
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Changes in Serum Adhesion Molecules, Chemokines, Cytokines, and Tissue Remodeling Factors in Euthyroid Women Without Thyroid Antibodies Who Are at Risk for Autoimmune Thyroid Disease: A Hypothesis on the Early Phases of the Endocrine Autoimmune Reaction
Published in The journal of clinical endocrinology and metabolism (01-06-2013)“…Background: The target glands in spontaneous animal models of endocrine autoimmune disease show, prior to the autoimmune reaction, growth and connective tissue…”
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Immune and neuroimmune alterations in mood disorders and schizophrenia
Published in International review of neurobiology (2011)“…A large number of publications over the past 20 years have indicated that immune system function is altered in schizophrenia and mood disorder patients. This…”
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Monocyte Gene-Expression Profiles Associated With Childhood-Onset Type 1 Diabetes and Disease Risk: A Study of Identical Twins
Published in Diabetes (New York, N.Y.) (01-07-2010)“…Monocytes in childhood-onset type 1 diabetes show distinct gene expression. We hypothesize that monocyte activation in monozygotic (MZ) twin pairs discordant…”
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