Search Results - "Drexhage, HA"

Defective maturation and function of antigen-presenting cells in type 1 diabetes by Jansen, A, van Hagen, M, Drexhage, H A

“…Macrophages and dendritic cells are important as antigen-presenting cells in the islet autoimmune response. We report decreased maturation of dendritic cells…”
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Thyroid peroxidase antibodies during gestation are a marker for subsequent depression postpartum by KUIJPENS, Johannes L, VADER, Huib L, DREXHAGE, Hemmo A, WIERSINGA, Wilmar M, VAN SON, Maarten J, POP, Victor J

“…Depression is not adequately diagnosed in many cases. Therefore, the question arises as to whether markers exist for depression. We investigated whether the…”
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A dynamic course of T cell defects in individuals at risk for mood disorders by Snijders, G, Schiweck, C, Mesman, E, Grosse, L, De Wit, H, Nolen, W.A, Drexhage, H.A, Hillegers, M.H.J

“…Highlights • A subtle, partial T cell deficiency has been found in bipolar offspring over time. • T cell subsets followed a dynamic course from adolescence…”
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Orbit-Infiltrating Mast Cells, Monocytes, and Macrophages Produce PDGF Isoforms that Orchestrate Orbital Fibroblast Activation in Graves' Ophthalmopathy by van Steensel, L, Paridaens, D, van Meurs, M, van Hagen, P. M, van den Bosch, W. A, Kuijpers, R. W. A. M, Drexhage, H. A, Hooijkaas, H, Dik, W. A

“…Purpose: Platelet-derived growth factors (PDGF) are regulators of fibroblast activity that may be involved in the pathophysiology of Graves' ophthalmopathy…”
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Subclinical hypothyroidism is an independent risk factor for atherosclerosis and myocardial infarction in elderly women : The Rotterdam Study by HAK, A. E, POLS, H. A. P, VISSER, T. J, DREXHAGE, H. A, HOFMAN, A, WITTEMAR, J. C. M

“…Overt hypothyroidism has been found to be associated with cardiovascular disease. Whether subclinical hypothyroidism and thyroid autoimmunity are also risk…”
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Premature Ovarian Failure and Ovarian Autoimmunity by Hoek, A.

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Low maternal free thyroxine concentrations during early pregnancy are associated with impaired psychomotor development in infancy by Pop, Victor J., Kuijpens, Johannes L., van Baar, Anneloes L., Verkerk, Gerda, van Son, Maarten M., de Vijlder, Jan J., Vulsma, Thomas, Wiersinga, Wilmar M., Drexhage, Hemmo A., Vader, Huib L.

“…BACKGROUND Maternal thyroid function during early pregnancy is an important determinant of early fetal brain development because the fetal thyroid is unable to…”
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Increased Serum Levels of MRP-8/14 in Type 1 Diabetes Induce an Increased Expression of CD11b and an Enhanced Adhesion of Circulating Monocytes to Fibronectin by BOUMA, Gerben, LAM-TSE, Wai Kwan, WIERENGA-WOLF, Annet F, DREXHAGE, Hemmo A, VERSNEL, Marjan A

“…Increased Serum Levels of MRP-8/14 in Type 1 Diabetes Induce an Increased Expression of CD11b and an Enhanced Adhesion of Circulating Monocytes to Fibronectin…”
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Subclinical hyperthyroidism and the risk of dementia. The Rotterdam study by Kalmijn, Sandra, Mehta, Kala M., Pols, Huibert A. P., Hofman, Albert, Drexhage, Hemmo A., Breteler, Monique M. B.

“…We investigated the prospective relationship between thyroid status and the risk of dementia and Alzheimer's disease among a random sample of 1843…”
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Immune cells, pancreas development, regeneration and type 1 diabetes by Homo-Delarche, Françoise, Drexhage, Hemmo A.

“…Macrophages (MΦs), dendritic cells (DCs) and lymphocytes are involved in the pathogenesis of type 1 diabetes (T1D). However, the presence of these cells is not…”
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Macrophages in the murine pancreas and their involvement in fetal endocrine development in vitro by Geutskens, S. B., Otonkoski, T., Pulkkinen, M‐A., Drexhage, H. A., Leenen, P. J. M.

“…Macrophages are a heterogeneous population of cells that belong to the mononuclear phagocyte system. They play an important role in tissue homeostasis and…”
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High numbers of circulating activated T cells and raised levels of serum IL-2 receptor in bipolar disorder by Breunis, M.Nadine, Kupka, Ralph W, Nolen, Willem A, Suppes, Trisha, Denicoff, Kirk D, Leverich, Gabriele S, Post, Robert M, Drexhage, Hemmo A

“…Previously, we found an increased prevalence of thyroid autoantibodies in patients with bipolar disorder. In the present study, we investigated other signs of…”
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A high prevalence of organ-specific autoimmunity in patients with bipolar disorder by Padmos, Roos C., Bekris, Lynn, Knijff, Esther M., Tiemeier, Henning, Kupka, Ralph W., Cohen, Dan, Nolen, Willem A., Lernmark, Åke, Drexhage, Hemmo A.

“…In a previous study, we reported an increased prevalence of thyroperoxidase antibodies (TPOA) in patients with bipolar disorder. Here we report the prevalence…”
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High rate of autoimmune thyroiditis in bipolar disorder: lack of association with lithium exposure by Kupka, Ralph W, Nolen, Willem A, Post, Robert M, McElroy, Susan L, Altshuler, Lori L, Denicoff, Kirk D, Frye, Mark A, Keck, Paul E, Leverich, Gabriele S, Rush, A.John, Suppes, Trisha, Pollio, Chad, Drexhage, Hemmo A

“…Background: We assessed the prevalence of thyroperoxidase antibodies (TPO-Abs) and thyroid failure in outpatients with bipolar disorder compared with two…”
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Are There More than Antibodies to the Thyroid-Stimulating Hormone Receptor that Meet the Eye in Graves’ Disease? by Drexhage, H. A

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Dendritic cells and macrophages are essential for the retention of lymphocytes in (peri)-insulitis of the nonobese diabetic mouse: a phagocyte depletion study by Nikolic, Tatjana, Geutskens, Sacha B, van Rooijen, Nico, Drexhage, Hemmo A, Leenen, Pieter J M

“…Dendritic cells (DC) and macrophages (Mphi) are present in high numbers in the pancreas of the non-obese diabetic (NOD) mouse during the diabetogenic process…”
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1-alpha,25-Dihydroxyvitamin D3 (1,25(OH)(2)D(3)) hampers the maturation of fully active immature dendritic cells from monocytes by Canning, M O, Grotenhuis, K, de Wit, H, Ruwhof, C, Drexhage, H A

“…To study the effects of the active metabolite of vitamin D(3), 1,25(OH)(2)D(3), an immunomodulatory hormone, on the generation of so-called immature dendritic…”
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Iodine and thyroid autoimmune disease in animal models by Ruwhof, C, Drexhage, H A

“…Thyroid autoimmune diseases are complex, polygenic afflictions the penetrance of which is heavily dependent on various environmental influences. In their…”
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In vivo effects of sex steroids on lymphocyte responsiveness and immunoglobulin levels in humans by GILTAY, E. J, FONK, J. C. M, VON BLOMBERG, B. M. E, DREXHAGE, H. A, SCHALKWIJK, C, GOOREN, L. J. G

“…The female predominance in several autoimmune diseases suggests a role for sex steroid hormones in disease susceptibility. We therefore investigated to what…”
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Bone Marrow Precursors of Nonobese Diabetic Mice Develop into Defective Macrophage-Like Dendritic Cells In Vitro by Nikolic, Tatjana, Bunk, Marjolijn, Drexhage, Hemmo A, Leenen, Pieter J. M

“…The NOD mouse spontaneously develops autoimmune diabetes. Dendritic cells (DC) play a crucial role in the autoimmune response. Previous studies have reported a…”
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